KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:ase00010 ase01200 ase01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:ase00010 ase01200 ase01230 ase01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:ase00010 ase00020 ase01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:ase00010 ase00020 ase00620 ase01200 ase01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:ase00020 ase01200 ase01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:ase00020 ase01200 ase01210 ase01230 ase01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:ase00020 ase01200 ase01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:ase00030 ase01200 ase01100 ase01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:ase00030 ase01200 ase01100 ase01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:ase00030 ase01200 ase01230 ase01100 ase01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:ase00030 ase00230 ase01200 ase01230 ase01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:ase00052 ase01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:ase00500 ase01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:ase00520 ase01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:ase00520 ase00052 ase01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:ase00520 ase01100]
M00012 Glyoxylate cycle [PATH:ase00630 ase01200 ase01100 ase01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:ase00280 ase00630 ase00640 ase01200 ase01100]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:ase00620 ase01200 ase01100 ase01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:ase00430 ase00620 ase01200 ase01100 ase01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:ase00920 ase01100 ase01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:ase00190]
M00150 Fumarate reductase, prokaryotes [PATH:ase00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:ase00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH:ase00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:ase00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:ase00061 ase01212 ase01100]
M00083 Fatty acid biosynthesis, elongation [PATH:ase00061 ase01212 ase01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:ase00061 ase00071 ase01212 ase01100]
M00087 beta-Oxidation [PATH:ase00071 ase01212 ase01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:ase00564 ase01100]

Nucleotide metabolism
Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:ase00230 ase01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ase00230 ase01240 ase01100]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:ase00230 ase01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:ase00240 ase01240 ase01100]
M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP [PATH:ase00240 ase01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:ase00260 ase00680 ase01200 ase01230 ase01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:ase00260 ase01230 ase01100 ase01110]
M00555 Betaine biosynthesis, choline => betaine [PATH:ase00260 ase01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:ase00270 ase00920 ase01200 ase01230 ase01100 ase01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:ase00260 ase00270 ase01230 ase01100]
M00017 Methionine biosynthesis, apartate => homoserine => methionine [PATH:ase00270 ase01230 ase01100]
M00035 Methionine degradation [PATH:ase00270 ase01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:ase00290 ase00770 ase01210 ase01230 ase01100 ase01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:ase00290 ase01230 ase01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:ase00290 ase01210 ase01230 ase01100 ase01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:ase00300 ase01230 ase01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:ase00220 ase01210 ase01230 ase01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:ase00220 ase01230 ase01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:ase00330 ase01230 ase01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:ase00340 ase01230 ase01100 ase01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:ase00400 ase01230 ase01100 ase01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:ase00400 ase01230 ase01100 ase01110]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:ase00250 ase00650 ase01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:ase00540 ase01100]
M00063 CMP-KDO biosynthesis [PATH:ase00540 ase01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:ase00540 ase01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:ase00740 ase01240 ase01100 ase01110]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:ase00750 ase01240 ase01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:ase00760 ase01240 ase01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:ase00770 ase01240 ase01100 ase01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:ase00770 ase01240 ase01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:ase00780 ase01240 ase01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:ase00780 ase01240 ase01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:ase00785 ase01240 ase01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:ase00790 ase00670 ase01240 ase01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:ase00860 ase01240 ase01100 ase01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:ase00860 ase01240 ase01100 ase01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:ase00860 ase01240 ase01100]
M00930 Menaquinone biosynthesis, futalosine pathway [PATH:ase00130 ase01240 ase01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:ase00900 ase01100 ase01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:ase00900 ase01100 ase01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:ase00521 ase00523 ase00541 ase01100 ase01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
M00814 Acarbose biosynthesis, sedoheptulopyranose-7P => acarbose [PATH:ase00525 ase01100 ase01110]

Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity