KEGG Modules
Pathway modules
Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH: bac00010 bac01200 bac01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH: bac00010 bac01200 bac01230 bac01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: bac00010 bac00020 bac01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: bac00010 bac00020 bac00620 bac00785 bac01200 bac01210 bac01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: bac00020 bac01200 bac01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: bac00020 bac01200 bac01210 bac01230 bac01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: bac00020 bac01200 bac01210 bac01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH: bac00030 bac01200 bac01100 bac01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH: bac00030 bac01200 bac01100 bac01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: bac00030 bac01200 bac01230 bac01100 bac01120]
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH: bac00030 bac01200 bac01230 bac01100 bac01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: bac00030 bac00230 bac01200 bac01230 bac01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH: bac00030 bac01200 bac01100 bac01120]
Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH: bac00040 bac01100]
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH: bac00040 bac00030 bac01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH: bac00052 bac01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH: bac00052 bac01100]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH: bac00040 bac00053 bac01240 bac01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH: bac00500 bac01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH: bac00500 bac01100]
M00012 Glyoxylate cycle [PATH: bac00630 bac01200 bac01100 bac01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH: bac00280 bac00630 bac00640 bac01200 bac01100]
M00982 Methylcitrate cycle [PATH: bac00640 bac00020 bac01200 bac01100 bac01120]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH: bac00562 bac01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH: bac00562 bac01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH: bac00562 bac01100]
Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
Lipid metabolism
Fatty acid metabolism
Sterol biosynthesis
M00101 Cholesterol biosynthesis, FPP => cholesterol [PATH: bac00100 bac01100]
M00103 Cholecalciferol biosynthesis [PATH: bac00100 bac01100]
M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate [PATH: bac01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH: bac01100]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH: bac01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH: bac01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH: bac01100]
M00977 C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone [PATH: bac01100]
Lipid metabolism
Nucleotide metabolism
Purine metabolism
Pyrimidine metabolism
Amino acid metabolism
Serine and threonine metabolism
Cysteine and methionine metabolism
Branched-chain amino acid metabolism
Lysine metabolism
Arginine and proline metabolism
Polyamine biosynthesis
Histidine metabolism
Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH: bac00400 bac01230 bac01100 bac01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH: bac00400 bac01230 bac01100 bac01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH: bac00400 bac01230 bac01100 bac01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH: bac00400 bac01230 bac01100]
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH: bac00350 bac01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH: bac00350 bac01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH: bac00350 bac01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH: bac00350 bac01220 bac01100 bac01120]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH: bac00380 bac01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH: bac00380 bac01100]
Other amino acid metabolism
Glycan metabolism
Nucleotide sugar biosynthesis
M00892 UDP-GlcNAc biosynthesis, eukaryotes, Fru-6P => UDP-GlcNAc [PATH: bac00520 bac01250 bac01100]
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH: bac00520 bac01250 bac01100]
M01003 UDP-GlcNAc biosynthesis, GlcNAc => UDP-GlcNAc [PATH: bac00520 bac01250 bac01100]
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH: bac00520 bac01250 bac01100 bac01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH: bac00520 bac01250 bac01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH: bac00520 bac01250 bac01100]
M01004 UDP-Galf biosynthesis, UDP-Glc => UDP-Galf [PATH: bac00520 bac00052 bac01250 bac01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH: bac00520 bac00053 bac01250 bac01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH: bac00520 bac00052 bac01250 bac01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH: bac00520 bac01250 bac01100]
M01001 GDP-L-Fuc biosynthesis, L-Fuc => GDP-L-Fuc [PATH: bac00520 bac01250 bac01100]
M01036 UDP-GalNAcA biosynthesis, UDP-GlcNAc => UDP-GalNAcA [PATH: bac00541]
M01035 UDP-ManNAc3NAcA biosynthesis, UDP-GlcNAc => UDP-ManNAc3NAcA [PATH: bac00541]
M00923 UDP-L-FucNAc biosynthesis, UDP-GlcNAc => UDP-L-FucNAc [PATH: bac00541 bac01250 bac01100]
M01009 UDP-QuiNAc biosynthesis, UDP-GlcNAc => UDP-QuiNAc [PATH: bac00541]
M01037 UDP-D-FucNAc4N biosynthesis, UDP-GlcNAc => UDP-D-FucNAc4N [PATH: bac00541]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH: bac00541 bac01250 bac01100]
M00955 CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc [PATH: bac00541 bac01250 bac01100]
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA [PATH: bac00541]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH: bac00541 bac01250 bac01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH: bac00521 bac00523 bac00541 bac01250 bac01100 bac01110]
M01016 GDP-L-Fuc biosynthesis, GDP-Man => GDP-L-Fuc [PATH: bac00541]
Glycan biosynthesis
M00072 N-glycosylation by oligosaccharyltransferase [PATH:bac01100]
M00073 N-glycan precursor trimming [PATH:bac01100]
M00075 N-glycan biosynthesis, complex type [PATH:bac01100]
M00056 O-glycan biosynthesis, mucin type core [PATH:bac01100]
M00872 O-glycan biosynthesis, mannose type (core M3) [PATH:bac01100]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH:bac01100]
M00983 GPI-anchor remodeling [PATH:bac01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:bac01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:bac01100]
M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer [PATH:bac01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:bac01100]
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00895 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/glycine) => TMP/TPP [PATH:bac00730 bac01240 bac01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:bac00730 bac01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:bac00740 bac01240 bac01100 bac01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:bac00750 bac01240 bac01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:bac00750 bac01240 bac01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:bac00760 bac01240 bac01100]
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:bac00380 bac00760 bac01240 bac01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:bac00770 bac01240 bac01100 bac01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:bac00770 bac01240 bac01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:bac00780 bac01240 bac01100]
M00573 Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin [PATH:bac00780 bac01240 bac01100]
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin [PATH:bac00780 bac01240 bac01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:bac00785 bac01240 bac01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:bac00785 bac01240 bac01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:bac00785 bac01240 bac01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:bac00790 bac00670 bac01240 bac01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:bac00790 bac01240 bac01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:bac00790 bac01240 bac01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:bac00790 bac01100]
M00140 C1-unit interconversion, prokaryotes [PATH:bac00670 bac01240 bac01100]
M00141 C1-unit interconversion, eukaryotes [PATH:bac00670 bac01240 bac01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:bac00860 bac01240 bac01100 bac01110]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:bac00860 bac01240 bac01100 bac01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:bac00860 bac01240 bac01100 bac01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:bac00860 bac01240 bac01100]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:bac00860 bac01240 bac01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:bac00860 bac01240 bac01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:bac00130 bac01240 bac01100 bac01110]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinone [PATH:bac00130 bac01240 bac01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:bac00130 bac01240 bac01100 bac01110]
M00930 Menaquinone biosynthesis, futalosine pathway [PATH:bac00130 bac01240 bac01100]
Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Signature modules
Gene set
Pathogenicity
Drug resistance
M00627 beta-Lactam resistance, Bla system [PATH:bac01501]
M00642 Multidrug resistance, efflux pump MexJK-OprM
M00643 Multidrug resistance, efflux pump MexXY-OprM
M00698 Multidrug resistance, efflux pump BpeEF-OprC
M00700 Multidrug resistance, efflux pump AbcA
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation
M00616 Sulfate-sulfur assimilation
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