KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:bld00010 bld01200 bld01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:bld00010 bld01200 bld01230 bld01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:bld00010 bld00020 bld01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:bld00020 bld01200 bld01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:bld00020 bld01200 bld01210 bld01230 bld01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:bld00020 bld01200 bld01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:bld00030 bld01200 bld01100 bld01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:bld00030 bld01200 bld01100 bld01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:bld00030 bld01200 bld01230 bld01100 bld01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:bld00030 bld00230 bld01200 bld01230 bld01100]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:bld00040 bld00030 bld01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:bld00052 bld01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:bld00500 bld01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:bld00520 bld01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:bld00520 bld00052 bld01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:bld00520 bld01100]
M00012 Glyoxylate cycle [PATH:bld00630 bld01200 bld01100 bld01110]

Energy metabolism
Carbon fixation
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:bld00430 bld00620 bld01200 bld01100 bld01120]

Methane metabolism
M00345 Formaldehyde assimilation, ribulose monophosphate pathway [PATH:bld00030 bld00680 bld01200 bld01230 bld01100 bld01120]

Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:bld00910 bld01100 bld01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:bld00920 bld01100 bld01120]

Photosynthesis
ATP synthesis
M00151 Cytochrome bc1 complex respiratory unit [PATH:bld00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH:bld00190]
M00416 Cytochrome aa3-600 menaquinol oxidase [PATH:bld00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:bld00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:bld00061 bld01212 bld01100]
M00083 Fatty acid biosynthesis, elongation [PATH:bld00061 bld01212 bld01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:bld00061 bld00071 bld01212 bld01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:bld00564 bld01100]

Nucleotide metabolism
Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:bld00230 bld01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bld00230 bld01240 bld01100]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:bld00230 bld01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:bld00240 bld01240 bld01100]

Amino acid metabolism
Serine and threonine metabolism
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:bld00260 bld01230 bld01100 bld01110]
M00555 Betaine biosynthesis, choline => betaine [PATH:bld00260 bld01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:bld00270 bld00920 bld01200 bld01230 bld01100 bld01110]
M00609 Cysteine biosynthesis, methionine => cysteine [PATH:bld00270 bld01230 bld01100]
M00017 Methionine biosynthesis, apartate => homoserine => methionine [PATH:bld00270 bld01230 bld01100]
M00034 Methionine salvage pathway [PATH:bld00270 bld01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:bld00290 bld00770 bld01210 bld01230 bld01100 bld01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:bld00290 bld01230 bld01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:bld00290 bld01210 bld01230 bld01100 bld01110]

Lysine metabolism
M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine [PATH:bld00300 bld01230 bld01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:bld00220 bld01210 bld01230 bld01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:bld00220 bld01230 bld01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:bld00330 bld01230 bld01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:bld00330 bld01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:bld00340 bld01230 bld01100 bld01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:bld00400 bld01230 bld01100 bld01110]

Other amino acid metabolism
Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00895 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/glycine) => TMP/TPP [PATH:bld00730 bld01240 bld01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:bld00730 bld01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:bld00740 bld01240 bld01100 bld01110]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:bld00750 bld01240 bld01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:bld00760 bld01240 bld01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:bld00770 bld01240 bld01100 bld01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:bld00770 bld01240 bld01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:bld00780 bld01240 bld01100]
M00573 Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin [PATH:bld00780 bld01240 bld01100]
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin [PATH:bld00780 bld01240 bld01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:bld00785 bld01240 bld01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:bld00790 bld00670 bld01240 bld01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:bld00790 bld01240 bld01100]
M00140 C1-unit interconversion, prokaryotes [PATH:bld00670 bld01240 bld01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:bld00860 bld01240 bld01100 bld01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:bld00860 bld01240 bld01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:bld00130 bld01240 bld01100 bld01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:bld00900 bld01100 bld01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:bld00900 bld01100 bld01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
M00877 Kanosamine biosynthesis glucose 6-phosphate => kanosamine [PATH:bld00998 bld01100 bld01110]

Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00627 beta-Lactam resistance, Bla system [PATH:bld01501]
M00700 Multidrug resistance, efflux pump AbcA

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity