KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:bxe00010 bxe01200 bxe01230 bxe01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:bxe00010 bxe00020 bxe01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:bxe00010 bxe00020 bxe00620 bxe00785 bxe01200 bxe01210 bxe01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:bxe00020 bxe01200 bxe01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:bxe00020 bxe01200 bxe01210 bxe01230 bxe01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:bxe00020 bxe01200 bxe01210 bxe01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:bxe00030 bxe01200 bxe01100 bxe01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:bxe00030 bxe01200 bxe01100 bxe01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:bxe00030 bxe01200 bxe01230 bxe01100 bxe01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:bxe00030 bxe00230 bxe01200 bxe01230 bxe01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:bxe00030 bxe01200 bxe01100 bxe01120]

Other carbohydrate metabolism
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:bxe00052 bxe01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:bxe00500 bxe01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:bxe00500 bxe01100 bxe01110]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:bxe00520 bxe01250 bxe01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:bxe00520 bxe01250 bxe01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:bxe00521 bxe00523 bxe00541 bxe01250 bxe01100 bxe01110]
M00012 Glyoxylate cycle [PATH:bxe00630 bxe01200 bxe01100 bxe01110]
M00982 Methylcitrate cycle [PATH:bxe00640 bxe00020 bxe01200 bxe01100 bxe01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:bxe00620 bxe00710 bxe01200 bxe01100 bxe01120]
M00169 CAM (Crassulacean acid metabolism), light [PATH:bxe00620 bxe00710 bxe01200 bxe01100 bxe01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:bxe00430 bxe00620 bxe00720 bxe01200 bxe01100 bxe01120]

Methane metabolism
Nitrogen metabolism
M00175 Nitrogen fixation, nitrogen => ammonia [PATH:bxe00910 bxe01310 bxe01100 bxe01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:bxe00910 bxe01310 bxe01100 bxe01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:bxe00920 bxe01100 bxe01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:bxe00190 bxe01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:bxe00190 bxe01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:bxe00190 bxe01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:bxe00190 bxe01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:bxe00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:bxe00190 bxe01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:bxe00190 bxe01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:bxe00061 bxe01212 bxe01100]
M00083 Fatty acid biosynthesis, elongation [PATH:bxe00061 bxe01212 bxe01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:bxe00061 bxe00071 bxe01212 bxe01100]
M00087 beta-Oxidation [PATH:bxe00071 bxe01212 bxe01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:bxe00564 bxe01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bxe00230 bxe01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bxe00230 bxe01232 bxe01240 bxe01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bxe00230 bxe01232 bxe01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bxe00230 bxe00240 bxe01232 bxe01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:bxe00230 bxe01232 bxe01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:bxe00230 bxe01232 bxe01100]
M00546 Purine degradation, xanthine => urea [PATH:bxe00230 bxe01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:bxe00240 bxe01232 bxe01240 bxe01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:bxe00240 bxe01232 bxe01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:bxe00240 bxe00410 bxe00770 bxe01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:bxe00260 bxe00680 bxe01200 bxe01230 bxe01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:bxe00260 bxe01230 bxe01100 bxe01110]
M00621 Glycine cleavage system [PATH:bxe00260 bxe00630 bxe00670 bxe00785 bxe01200 bxe01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:bxe00260 bxe00670 bxe01100]
M00975 Betaine degradation, bacteria, betaine => pyruvate [PATH:bxe00260 bxe01100]
M00919 Ectoine degradation, ectoine => aspartate [PATH:bxe00260 bxe01100 bxe01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:bxe00270 bxe00920 bxe01200 bxe01230 bxe01100 bxe01110]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:bxe00290 bxe00770 bxe01210 bxe01230 bxe01100 bxe01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:bxe00290 bxe01230 bxe01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:bxe00290 bxe01210 bxe01230 bxe01100 bxe01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:bxe00300 bxe01230 bxe01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:bxe00220 bxe01210 bxe01230 bxe01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:bxe00220 bxe01230 bxe01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:bxe00330 bxe01230 bxe01100]
M00970 Proline degradation, proline => glutamate [PATH:bxe00330 bxe01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:bxe00330 bxe01100]

Polyamine biosynthesis
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:bxe00330 bxe01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:bxe00340 bxe01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:bxe00400 bxe01230 bxe01100 bxe01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:bxe00400 bxe01230 bxe01100 bxe01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:bxe00400 bxe01230 bxe01100 bxe01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:bxe00400 bxe01230 bxe01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:bxe00350 bxe01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:bxe00350 bxe01220 bxe01100 bxe01120]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:bxe00250 bxe00650 bxe01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:bxe00480 bxe01240 bxe01100]
M00948 Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate [PATH:bxe00470 bxe01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:bxe00540 bxe01250 bxe01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:bxe00540 bxe01250 bxe01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:bxe00760 bxe01240 bxe01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:bxe00770 bxe01240 bxe01100 bxe01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:bxe00770 bxe01240 bxe01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:bxe00780 bxe01240 bxe01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:bxe00785 bxe01240 bxe01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:bxe00790 bxe00670 bxe01240 bxe01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:bxe00790 bxe01240 bxe01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:bxe00790 bxe01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:bxe00860 bxe01240 bxe01100 bxe01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:bxe00860 bxe01240 bxe01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:bxe00130 bxe01240 bxe01100 bxe01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation
M00419 Cymene degradation, p-cymene => p-cumate [PATH:bxe00622 bxe01220 bxe01100 bxe01120]
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:bxe00362 bxe00622 bxe01220 bxe01100 bxe01120]
M00637 Anthranilate degradation, anthranilate => catechol [PATH:bxe00627 bxe01100 bxe01120]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:bxe00362 bxe01220 bxe01100 bxe01120]
M00539 Cumate degradation, p-cumate => 2-oxopent-4-enoate + 2-methylpropanoate [PATH:bxe00622 bxe01220 bxe01100 bxe01120]
M00543 Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate [PATH:bxe00621 bxe01220 bxe01100 bxe01120]
M00545 Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA [PATH:bxe00360 bxe01220 bxe01100 bxe01120]

Gene set
Pathogenicity
Drug resistance
M00642 Multidrug resistance, efflux pump MexJK-OprM
M00698 Multidrug resistance, efflux pump BpeEF-OprC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation