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KEGG Modules
Pathway modules
Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH: cbr00010 cbr01200 cbr01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH: cbr00010 cbr01200 cbr01230 cbr01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: cbr00010 cbr00020 cbr01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: cbr00010 cbr00020 cbr00620 cbr00785 cbr01200 cbr01210 cbr01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: cbr00020 cbr01200 cbr01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: cbr00020 cbr01200 cbr01210 cbr01230 cbr01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: cbr00020 cbr01200 cbr01210 cbr01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH: cbr00030 cbr01200 cbr01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose-6P => ribulose-5P [PATH: cbr00030 cbr01200 cbr01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose-6P => ribose-5P [PATH: cbr00030 cbr01200 cbr01230 cbr01100]
M00005 PRPP biosynthesis, ribose-5P => PRPP [PATH: cbr00030 cbr00230 cbr01200 cbr01230 cbr01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH: cbr00030 cbr01200 cbr01100]
Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH: cbr00040 cbr01100]
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde-3P [PATH: cbr00040 cbr00030 cbr01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde-3P [PATH: cbr00040 cbr00030 cbr01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH: cbr00052 cbr01100]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH: cbr00040 cbr00053 cbr01240 cbr01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH: cbr00053 cbr01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH: cbr00500 cbr01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH: cbr00500 cbr01100]
M00012 Glyoxylate cycle [PATH: cbr00630 cbr01200 cbr01100]
M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA [PATH: cbr00410 cbr00640 cbr01200 cbr01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH: cbr00280 cbr00630 cbr00640 cbr01200 cbr01100]
M00982 Methylcitrate cycle [PATH: cbr00640 cbr00020 cbr01200 cbr01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH: cbr00562 cbr01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH: cbr00562 cbr01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH: cbr00562 cbr01100]
Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
M00597 Anoxygenic photosystem II
ATP synthesis
Lipid metabolism
Fatty acid metabolism
Sterol biosynthesis
M00103 Cholecalciferol biosynthesis [PATH:cbr00100 cbr01100]
M00862 beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA [PATH:cbr01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH:cbr01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH:cbr01100]
Lipid metabolism
Nucleotide metabolism
Purine metabolism
Pyrimidine metabolism
Amino acid metabolism
Serine and threonine metabolism
Cysteine and methionine metabolism
Branched-chain amino acid metabolism
Lysine metabolism
Arginine and proline metabolism
Polyamine biosynthesis
Histidine metabolism
Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH: cbr00400 cbr01230 cbr01100]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH: cbr00400 cbr01230 cbr01100]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH: cbr00400 cbr01230 cbr01100]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH: cbr00400 cbr01230 cbr01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH: cbr00350 cbr01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH: cbr00350 cbr01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH: cbr00350 cbr01100]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH: cbr00380 cbr01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH: cbr00380 cbr01100]
Other amino acid metabolism
Glycan metabolism
Nucleotide sugar biosynthesis
M00892 UDP-GlcNAc biosynthesis, eukaryotes, Fru-6P => UDP-GlcNAc [PATH: cbr00520 cbr01250 cbr01100]
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH: cbr00520 cbr01250 cbr01100]
M01003 UDP-GlcNAc biosynthesis, GlcNAc => UDP-GlcNAc [PATH: cbr00520 cbr01250 cbr01100]
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH: cbr00520 cbr01250 cbr01100 cbr01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH: cbr00520 cbr01250 cbr01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH: cbr00520 cbr01250 cbr01100]
M01004 UDP-Galf biosynthesis, UDP-Glc => UDP-Galf [PATH: cbr00520 cbr00052 cbr01250 cbr01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH: cbr00520 cbr00053 cbr01250 cbr01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH: cbr00520 cbr00052 cbr01250 cbr01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH: cbr00520 cbr00051 cbr01250 cbr01100]
M01015 GDP-Man biosynthesis, Man => GDP-Man [PATH: cbr00520 cbr00051 cbr01250 cbr01100]
M01001 GDP-L-Fuc biosynthesis, L-Fuc => GDP-L-Fuc [PATH: cbr00520 cbr01250 cbr01100]
M01036 UDP-GalNAcA biosynthesis, UDP-GlcNAc => UDP-GalNAcA [PATH: cbr00541 cbr01250 cbr01100]
M01035 UDP-ManNAc3NAcA biosynthesis, UDP-GlcNAc => UDP-ManNAc3NAcA [PATH: cbr00541 cbr01250 cbr01100]
M00063 CMP-KDO biosynthesis, ribulose-5P => CMP-KDO [PATH: cbr00541 cbr01250 cbr01100]
M00955 CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc [PATH: cbr00541 cbr01250 cbr01100]
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA [PATH: cbr00541 cbr01250 cbr01100]
M00064 ADP-LDmanHep biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH: cbr00541 cbr01250 cbr01100]
M00761 Und-P-alpha-L-Ara4N biosynthesis, UDP-Glc => UDP-L-Ara4FN => Und-P-alpha-L-Ara4N [PATH: cbr00541 cbr01250 cbr01100]
M00793 dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha [PATH: cbr00541 cbr01250 cbr01100]
M01025 dTDP-D-Fuc4NAc biosynthesis, Glc-1P => dTDP-D-Fuc4NAc [PATH: cbr00541 cbr01250 cbr01100]
M01016 GDP-L-Fuc biosynthesis, GDP-Man => GDP-L-Fuc [PATH: cbr00541 cbr00051 cbr01250 cbr01100]
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH: cbr00730 cbr01240 cbr01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH: cbr00730 cbr01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH: cbr00740 cbr01240 cbr01100]
M00124 Pyridoxal phosphate biosynthesis, erythrose-4P => pyridoxal-P [PATH: cbr00750 cbr01240 cbr01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH: cbr00760 cbr01240 cbr01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH: cbr00770 cbr01240 cbr01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH: cbr00770 cbr01240 cbr01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH: cbr00780 cbr01240 cbr01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH: cbr00780 cbr01240 cbr01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH: cbr00785 cbr01240 cbr01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH: cbr00785 cbr01240 cbr01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH: cbr00785 cbr01240 cbr01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH: cbr00790 cbr00670 cbr01240 cbr01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH: cbr00790 cbr01240 cbr01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH: cbr00790 cbr01240 cbr01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH: cbr00790 cbr01100]
M00140 C1-unit interconversion, prokaryotes [PATH: cbr00670 cbr01240 cbr01100]
M00141 C1-unit interconversion, eukaryotes [PATH: cbr00670 cbr01240 cbr01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH: cbr00860 cbr01240 cbr01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH: cbr00860 cbr01240 cbr01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH: cbr00860 cbr01240 cbr01100]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH: cbr00860 cbr01240 cbr01100]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH: cbr00860 cbr01240 cbr01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH: cbr00860 cbr01240 cbr01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH: cbr00130 cbr01240 cbr01100]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH: cbr00130 cbr01240 cbr01100]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinone [PATH: cbr00130 cbr01240 cbr01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH: cbr00130 cbr01240 cbr01100]
Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Terpenoid biosynthesis
M00097 Lycopene biosynthesis, geranylgeranyl-PP => lycopene [PATH:cbr01100]
M01039 Spirilloxanthin biosynthesis, bacteria, lycopene => spirilloxanthin [PATH:cbr01100]
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Biosynthesis of other compounds
M01047 Juvenile hormone biosynthesis, insects, farnesyl-PP => juvenile hormone III [PATH: cbr01100]
M01013 Molting hormone biosynthesis, insects, 2,22,25-trideoxyecdysone => ecdysone => 20-hydroxyecdysone [PATH: cbr01100]
Xenobiotics biodegradation
Aromatics degradation
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:cbr01100]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:cbr01100]
Signature modules
Gene set
Pathogenicity
M00857 Salmonella enterica pathogenicity signature, Vi antigen
Drug resistance
M00696 Multidrug resistance, efflux pump AcrEF-TolC
M00697 Multidrug resistance, efflux pump MdtEF-TolC
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation
M00616 Sulfate-sulfur assimilation
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