KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:cbu00010 cbu01200 cbu01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:cbu00010 cbu01200 cbu01230 cbu01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:cbu00010 cbu00020 cbu01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:cbu00010 cbu00020 cbu00620 cbu00785 cbu01200 cbu01210 cbu01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:cbu00020 cbu01200 cbu01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:cbu00020 cbu01200 cbu01210 cbu01230 cbu01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:cbu00020 cbu01200 cbu01210 cbu01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:cbu00030 cbu01200 cbu01100 cbu01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:cbu00030 cbu01200 cbu01100 cbu01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:cbu00030 cbu01200 cbu01230 cbu01100 cbu01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:cbu00030 cbu00230 cbu01200 cbu01230 cbu01100]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:cbu00040 cbu00030 cbu01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:cbu00052 cbu01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:cbu00500 cbu01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:cbu00500 cbu01100]
M00982 Methylcitrate cycle [PATH:cbu00640 cbu00020 cbu01200 cbu01100 cbu01120]

Energy metabolism
Carbon fixation
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:cbu00430 cbu00620 cbu00720 cbu01200 cbu01100 cbu01120]

Methane metabolism
Nitrogen metabolism
M00175 Nitrogen fixation, nitrogen => ammonia [PATH:cbu00910 cbu01100 cbu01120]

Sulfur metabolism
M00986 Sulfur reduction, sulfur => sulfide [PATH:cbu00920 cbu01320 cbu01100 cbu01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:cbu00190 cbu01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:cbu00190 cbu01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:cbu00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:cbu00190 cbu01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:cbu00190 cbu01100]
M00159 V/A-type ATPase, prokaryotes [PATH:cbu00190 cbu01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:cbu00061 cbu01212 cbu01100]
M00083 Fatty acid biosynthesis, elongation [PATH:cbu00061 cbu01212 cbu01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:cbu00564 cbu01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cbu00230 cbu01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cbu00230 cbu01232 cbu01240 cbu01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cbu00230 cbu01232 cbu01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cbu00230 cbu00240 cbu01232 cbu01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:cbu00240 cbu01240 cbu01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:cbu00240 cbu01232 cbu01240 cbu01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:cbu00240 cbu01232 cbu01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:cbu00260 cbu00680 cbu01200 cbu01230 cbu01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:cbu00260 cbu01230 cbu01100 cbu01110]
M00621 Glycine cleavage system [PATH:cbu00260 cbu00630 cbu00670 cbu00785 cbu01200 cbu01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:cbu00270 cbu00920 cbu01320 cbu01200 cbu01230 cbu01100 cbu01110]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:cbu00290 cbu00770 cbu01210 cbu01230 cbu01100 cbu01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:cbu00290 cbu01230 cbu01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:cbu00290 cbu01210 cbu01230 cbu01100 cbu01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:cbu00280 cbu01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:cbu00300 cbu01230 cbu01100]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:cbu00300 cbu01230 cbu01100 cbu01110]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:cbu00220 cbu01210 cbu01230 cbu01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:cbu00220 cbu01230 cbu01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:cbu00330 cbu01230 cbu01100]
M00970 Proline degradation, proline => glutamate [PATH:cbu00330 cbu01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:cbu00330 cbu01100]
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:cbu00330 cbu01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:cbu00330 cbu01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:cbu01230 cbu01100 cbu01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:cbu00400 cbu01230 cbu01100 cbu01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:cbu00400 cbu01230 cbu01100 cbu01110]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:cbu00480 cbu01240 cbu01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:cbu00520 cbu01250 cbu01100]
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH:cbu00520 cbu01250 cbu01100 cbu01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:cbu00520 cbu01250 cbu01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:cbu00520 cbu00053 cbu01250 cbu01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:cbu00520 cbu00052 cbu01250 cbu01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:cbu00520 cbu01250 cbu01100]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:cbu00541 cbu01250 cbu01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:cbu00521 cbu00523 cbu00541 cbu01250 cbu01100 cbu01110]
M01016 GDP-L-Fuc biosynthesis, GDP-Man => GDP-L-Fuc [PATH:cbu00541]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:cbu00730 cbu01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:cbu00750 cbu01240 cbu01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:cbu00760 cbu01240 cbu01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:cbu00770 cbu01240 cbu01100 cbu01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:cbu00770 cbu01240 cbu01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:cbu00780 cbu01240 cbu01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:cbu00785 cbu01240 cbu01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:cbu00790 cbu00670 cbu01240 cbu01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:cbu00790 cbu01100]
M00140 C1-unit interconversion, prokaryotes [PATH:cbu00670 cbu01240 cbu01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:cbu00860 cbu01240 cbu01100 cbu01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:cbu00860 cbu01240 cbu01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:cbu00860 cbu01240 cbu01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity