KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:ebi00010 ebi01200 ebi01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:ebi00010 ebi01200 ebi01230 ebi01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:ebi00010 ebi00020 ebi01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:ebi00010 ebi00020 ebi00620 ebi00785 ebi01200 ebi01210 ebi01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:ebi00020 ebi01200 ebi01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:ebi00020 ebi01200 ebi01210 ebi01230 ebi01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:ebi00020 ebi01200 ebi01210 ebi01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:ebi00030 ebi01200 ebi01100 ebi01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:ebi00030 ebi01200 ebi01100 ebi01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:ebi00030 ebi01200 ebi01230 ebi01100 ebi01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:ebi00030 ebi00230 ebi01200 ebi01230 ebi01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:ebi00030 ebi01200 ebi01100 ebi01120]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:ebi00040 ebi00030 ebi01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:ebi00040 ebi00030 ebi01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:ebi00052 ebi01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:ebi00052 ebi01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:ebi00500 ebi01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:ebi00500 ebi01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:ebi00500 ebi01100 ebi01110]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:ebi00520 ebi01250 ebi01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:ebi00520 ebi00052 ebi01250 ebi01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:ebi00520 ebi01250 ebi01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:ebi00520 ebi01100]
M00012 Glyoxylate cycle [PATH:ebi00630 ebi01200 ebi01100 ebi01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:ebi00620 ebi00710 ebi01200 ebi01100 ebi01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:ebi00430 ebi00620 ebi00720 ebi01200 ebi01100 ebi01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:ebi00910 ebi01100 ebi01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:ebi00920 ebi01100 ebi01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:ebi00190 ebi01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:ebi00190 ebi01100]
M00150 Fumarate reductase, prokaryotes [PATH:ebi00190 ebi01100]
M00417 Cytochrome o ubiquinol oxidase [PATH:ebi00190 ebi01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:ebi00190 ebi01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:ebi00061 ebi01212 ebi01100]
M00083 Fatty acid biosynthesis, elongation [PATH:ebi00061 ebi01212 ebi01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:ebi00061 ebi00071 ebi01212 ebi01100]
M00087 beta-Oxidation [PATH:ebi00071 ebi01212 ebi01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:ebi00564 ebi01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ebi00230 ebi01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ebi00230 ebi01232 ebi01240 ebi01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ebi00230 ebi01232 ebi01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ebi00230 ebi00240 ebi01232 ebi01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:ebi00230 ebi01232 ebi01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:ebi00230 ebi01232 ebi01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:ebi00240 ebi01240 ebi01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:ebi00240 ebi01232 ebi01240 ebi01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:ebi00240 ebi01232 ebi01100]
M00939 Pyrimidine degradation, uracil => 3-hydroxypropanoate [PATH:ebi00240 ebi01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:ebi00260 ebi00680 ebi01200 ebi01230 ebi01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:ebi00260 ebi01230 ebi01100 ebi01110]
M00621 Glycine cleavage system [PATH:ebi00260 ebi00630 ebi00785 ebi01200 ebi01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:ebi00260 ebi01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:ebi00270 ebi00920 ebi01200 ebi01230 ebi01100 ebi01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:ebi00270 ebi01230 ebi01100]
M00034 Methionine salvage pathway [PATH:ebi00270 ebi01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:ebi00290 ebi00770 ebi01210 ebi01230 ebi01100 ebi01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:ebi00290 ebi01230 ebi01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:ebi00290 ebi01210 ebi01230 ebi01100 ebi01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:ebi00300 ebi01230 ebi01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:ebi00220 ebi01210 ebi01230 ebi01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:ebi00220 ebi01230 ebi01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:ebi00330 ebi01230 ebi01100]
M00970 Proline degradation, proline => glutamate [PATH:ebi00330 ebi01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:ebi00330 ebi01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:ebi00330 ebi01100]
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:ebi00330 ebi01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:ebi00340 ebi01230 ebi01100 ebi01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:ebi00340 ebi01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:ebi00400 ebi01230 ebi01100 ebi01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:ebi00400 ebi01230 ebi01100 ebi01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:ebi00400 ebi01230 ebi01100 ebi01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:ebi00400 ebi01230 ebi01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:ebi00480 ebi01240 ebi01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:ebi00540 ebi01100]
M00063 CMP-KDO biosynthesis [PATH:ebi00540 ebi01250 ebi01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:ebi00540 ebi01250 ebi01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:ebi00730 ebi01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:ebi00740 ebi01240 ebi01100 ebi01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:ebi00750 ebi01240 ebi01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:ebi00760 ebi01240 ebi01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:ebi00770 ebi01240 ebi01100 ebi01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:ebi00770 ebi01240 ebi01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:ebi00780 ebi01240 ebi01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:ebi00785 ebi01240 ebi01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:ebi00790 ebi00670 ebi01240 ebi01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:ebi00790 ebi01240 ebi01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:ebi00860 ebi01240 ebi01100 ebi01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:ebi00860 ebi01240 ebi01100 ebi01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:ebi00130 ebi01240 ebi01100 ebi01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:ebi00130 ebi01240 ebi01100 ebi01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:ebi00900 ebi01100 ebi01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:ebi00900 ebi01100 ebi01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:ebi00521 ebi00523 ebi00541 ebi01250 ebi01100 ebi01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation