KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:eja00010 eja01200 eja01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:eja00010 eja01200 eja01230 eja01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:eja00010 eja00020 eja01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:eja00010 eja00020 eja00620 eja00785 eja01200 eja01210 eja01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:eja00020 eja01200 eja01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:eja00020 eja01200 eja01210 eja01230 eja01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:eja00020 eja01200 eja01210 eja01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:eja00030 eja01200 eja01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:eja00030 eja01200 eja01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:eja00030 eja01200 eja01230 eja01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:eja00030 eja00230 eja01200 eja01230 eja01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:eja00052 eja01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:eja00500 eja01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:eja00500 eja01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:eja00280 eja00630 eja00640 eja01200 eja01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:eja00562 eja01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:eja00562 eja01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:eja00562 eja01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:eja00190 eja01100]
M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:eja00190 eja01100]
M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:eja00190 eja01100]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:eja00190 eja01100]
M00160 V-type ATPase, eukaryotes [PATH:eja00190 eja01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:eja00061 eja01212 eja01100]
M00083 Fatty acid biosynthesis, elongation [PATH:eja00061 eja01212 eja01100]
M00873 Fatty acid biosynthesis in mitochondria, animals [PATH:eja00061 eja01212 eja01100]
M00085 Fatty acid elongation in mitochondria [PATH:eja00062 eja01212 eja01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:eja00062 eja01040 eja01212 eja01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:eja00061 eja00071 eja01212 eja01100]
M00087 beta-Oxidation [PATH:eja00071 eja01212 eja01100]
M00861 beta-Oxidation, peroxisome, VLCFA [PATH:eja01040 eja01212 eja01100]

Sterol biosynthesis
M00101 Cholesterol biosynthesis, FPP => cholesterol [PATH:eja00100 eja01100]
M00103 Cholecalciferol biosynthesis [PATH:eja00100 eja01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH:eja00140 eja01100]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH:eja00140 eja01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH:eja00140 eja01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH:eja00140 eja01100]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:eja00561 eja01100]
M00098 Acylglycerol degradation [PATH:eja00561 eja01100]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:eja00564 eja01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:eja00564 eja01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:eja00564 eja01100]
M00094 Ceramide biosynthesis [PATH:eja00600 eja01100]
M00066 Lactosylceramide biosynthesis [PATH:eja00600 eja01100]
M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:eja00600 eja00565 eja01100]
M00099 Sphingosine biosynthesis [PATH:eja00600 eja01100]
M00100 Sphingosine degradation [PATH:eja00600 eja01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:eja00230 eja01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:eja00230 eja01232 eja01240 eja01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:eja00230 eja01232 eja01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:eja00230 eja00240 eja01232 eja01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:eja00230 eja01232 eja01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:eja00230 eja01232 eja01100]
M00546 Purine degradation, xanthine => urea [PATH:eja00230 eja01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:eja00240 eja01240 eja01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:eja00240 eja01232 eja01240 eja01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:eja00240 eja01232 eja01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:eja00240 eja00410 eja00770 eja01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:eja00260 eja01200 eja01230 eja01100]
M00621 Glycine cleavage system [PATH:eja00260 eja00630 eja00670 eja00785 eja01200 eja01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:eja00260 eja00670 eja01100]
M00974 Betaine metabolism, animals, betaine => glycine [PATH:eja00260 eja00670 eja01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:eja00260 eja00270 eja00670 eja01230 eja01100]
M00035 Methionine degradation [PATH:eja00270 eja00670 eja01100]

Branched-chain amino acid metabolism
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:eja00280 eja01100]

Lysine metabolism
M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:eja00310 eja01210 eja01100]

Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:eja00220 eja01230 eja01100]
M00029 Urea cycle [PATH:eja00220 eja01230 eja01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:eja00330 eja01230 eja01100]
M00970 Proline degradation, proline => glutamate [PATH:eja00330 eja01100]
M00972 Proline metabolism [PATH:eja00330 eja01100]
M00047 Creatine pathway [PATH:eja00330 eja00260 eja01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:eja00330 eja01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:eja00330 eja01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:eja00340 eja01100]

Aromatic amino acid metabolism
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:eja00350 eja01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:eja00350 eja01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:eja00350 eja01100]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH:eja00380 eja01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:eja00380 eja01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:eja00250 eja00650 eja01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:eja00480 eja01240 eja01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00892 UDP-GlcNAc biosynthesis, eukaryotes, Fru-6P => UDP-GlcNAc [PATH:eja00520 eja01250 eja01100]
M01003 UDP-GlcNAc biosynthesis, GlcNAc => UDP-GlcNAc [PATH:eja00520 eja01250 eja01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:eja00520 eja01250 eja01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:eja00520 eja00052 eja01250 eja01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:eja00520 eja00051 eja01250 eja01100]
M01015 GDP-Man biosynthesis, Man => GDP-Man [PATH:eja00520 eja00051 eja01250 eja01100]
M01001 GDP-L-Fuc biosynthesis, L-Fuc => GDP-L-Fuc [PATH:eja00520 eja01250 eja01100]
M00955 CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc [PATH:eja00541 eja01250 eja01100]
M01016 GDP-L-Fuc biosynthesis, GDP-Man => GDP-L-Fuc [PATH:eja00541 eja00051 eja01250 eja01100]

Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:eja00510 eja01100]
M00072 N-glycosylation by oligosaccharyltransferase [PATH:eja00510 eja00513 eja01100]
M00073 N-glycan precursor trimming [PATH:eja00510 eja01100]
M00075 N-glycan biosynthesis, complex type [PATH:eja00510 eja01100]
M00872 O-glycan biosynthesis, mannose type (core M3) [PATH:eja00515 eja01100]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH:eja00563 eja01100]
M00983 GPI-anchor remodeling [PATH:eja00563 eja01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:eja00601 eja01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:eja00601 eja01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:eja00604 eja01100]

Glycosaminoglycan metabolism
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH:eja00532 eja00534 eja01100]
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:eja00532 eja01100]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:eja00534 eja01100]
M00076 Dermatan sulfate degradation [PATH:eja00531 eja01100]
M00077 Chondroitin sulfate degradation [PATH:eja00531 eja01100]
M00078 Heparan sulfate degradation [PATH:eja00531 eja01100]
M00079 Keratan sulfate degradation [PATH:eja00531 eja01100]

Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:eja00380 eja00760 eja01240 eja01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:eja00770 eja01240 eja01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:eja00785 eja01240 eja01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:eja00785 eja01240 eja01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:eja00790 eja01240 eja01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:eja00790 eja01240 eja01100]
M00141 C1-unit interconversion, eukaryotes [PATH:eja00670 eja01240 eja01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:eja00860 eja01240 eja01100]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinone [PATH:eja00130 eja01240 eja01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:eja00900 eja01100]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:eja00900 eja01100]

Terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Biosynthesis of other compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity