KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:epe00010 epe01200 epe01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:epe00010 epe01200 epe01230 epe01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:epe00010 epe00020 epe01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:epe00010 epe00020 epe00620 epe00785 epe01200 epe01210 epe01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:epe00020 epe01200 epe01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:epe00020 epe01200 epe01210 epe01230 epe01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:epe00020 epe01200 epe01210 epe01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:epe00030 epe01200 epe01100 epe01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:epe00030 epe01200 epe01100 epe01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:epe00030 epe01200 epe01230 epe01100 epe01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:epe00030 epe00230 epe01200 epe01230 epe01100]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:epe00040 epe00030 epe01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:epe00040 epe00030 epe01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:epe00500 epe01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:epe00500 epe01100 epe01110]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:epe00520 epe01250 epe01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:epe00520 epe01100]
M00012 Glyoxylate cycle [PATH:epe00630 epe01200 epe01100 epe01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:epe00620 epe00710 epe01200 epe01100 epe01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:epe00430 epe00620 epe00720 epe01200 epe01100 epe01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:epe00920 epe01100 epe01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:epe00190 epe01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:epe00190 epe01100]
M00150 Fumarate reductase, prokaryotes [PATH:epe00190 epe01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:epe00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:epe00190 epe01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:epe00190 epe01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:epe00061 epe01212 epe01100]
M00083 Fatty acid biosynthesis, elongation [PATH:epe00061 epe01212 epe01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:epe00061 epe00071 epe01212 epe01100]
M00087 beta-Oxidation [PATH:epe00071 epe01212 epe01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:epe00564 epe01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:epe00230 epe01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:epe00230 epe01232 epe01240 epe01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:epe00230 epe01232 epe01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:epe00230 epe00240 epe01232 epe01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:epe00240 epe01240 epe01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:epe00240 epe01232 epe01240 epe01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:epe00240 epe01232 epe01100]
M00939 Pyrimidine degradation, uracil => 3-hydroxypropanoate [PATH:epe00240 epe01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:epe00260 epe00680 epe01200 epe01230 epe01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:epe00260 epe01230 epe01100 epe01110]
M00621 Glycine cleavage system [PATH:epe00260 epe00630 epe00785 epe01200 epe01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:epe00260 epe01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:epe00270 epe00920 epe01200 epe01230 epe01100 epe01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:epe00270 epe01230 epe01100]
M00034 Methionine salvage pathway [PATH:epe00270 epe01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:epe00290 epe00770 epe01210 epe01230 epe01100 epe01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:epe00290 epe01230 epe01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:epe00290 epe01210 epe01230 epe01100 epe01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:epe00300 epe01230 epe01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:epe00220 epe01210 epe01230 epe01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:epe00220 epe01230 epe01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:epe00330 epe01230 epe01100]
M00970 Proline degradation, proline => glutamate [PATH:epe00330 epe01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:epe00330 epe01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:epe00330 epe01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:epe00340 epe01230 epe01100 epe01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:epe00340 epe01100]

Aromatic amino acid metabolism
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:epe00400 epe01230 epe01100 epe01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:epe00400 epe01230 epe01100 epe01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:epe00400 epe01230 epe01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:epe00350 epe01220 epe01100 epe01120]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:epe00480 epe01240 epe01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:epe00540 epe01100]
M00063 CMP-KDO biosynthesis [PATH:epe00540 epe01250 epe01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:epe00540 epe01250 epe01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:epe00730 epe01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:epe00740 epe01240 epe01100 epe01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:epe00750 epe01240 epe01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:epe00760 epe01240 epe01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:epe00770 epe01240 epe01100 epe01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:epe00770 epe01240 epe01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:epe00780 epe01240 epe01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:epe00785 epe01240 epe01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:epe00790 epe00670 epe01240 epe01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:epe00790 epe01240 epe01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:epe00860 epe01240 epe01100 epe01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:epe00860 epe01240 epe01100 epe01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:epe00130 epe01240 epe01100 epe01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:epe00130 epe01240 epe01100 epe01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:epe00900 epe01100 epe01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:epe00900 epe01100 epe01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:epe00521 epe00523 epe00541 epe01250 epe01100 epe01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation