KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:fes00010 fes01200 fes01230 fes01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:fes00010 fes00020 fes01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:fes00010 fes00020 fes00620 fes01200 fes01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:fes00020 fes01200 fes01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:fes00020 fes01200 fes01210 fes01230 fes01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:fes00020 fes01200 fes01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:fes00030 fes01200 fes01100 fes01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:fes00030 fes01200 fes01100 fes01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:fes00030 fes01200 fes01230 fes01100 fes01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:fes00030 fes00230 fes01200 fes01230 fes01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:fes00030 fes01200 fes01100 fes01120]

Other carbohydrate metabolism
M00012 Glyoxylate cycle [PATH:fes00630 fes01200 fes01100 fes01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:fes00620 fes01200 fes01100 fes01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:fes00430 fes00620 fes01200 fes01100 fes01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:fes00910 fes01100 fes01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:fes00920 fes01100 fes01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:fes00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:fes00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH:fes00190]
M00153 Cytochrome bd ubiquinol oxidase [PATH:fes00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:fes00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:fes00061 fes01212 fes01100]
M00083 Fatty acid biosynthesis, elongation [PATH:fes00061 fes01212 fes01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:fes00061 fes00071 fes01212 fes01100]
M00087 beta-Oxidation [PATH:fes00071 fes01212 fes01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:fes00564 fes01100]

Nucleotide metabolism
Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:fes00230 fes01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:fes00230 fes01240 fes01100]
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:fes00230 fes01100]

Pyrimidine metabolism
M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP [PATH:fes00240 fes01240 fes01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:fes00240 fes01240 fes01100]
M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP [PATH:fes00240 fes01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:fes00260 fes00680 fes01200 fes01230 fes01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:fes00260 fes01230 fes01100 fes01110]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:fes00270 fes00920 fes01200 fes01230 fes01100 fes01110]
M00017 Methionine biosynthesis, apartate => homoserine => methionine [PATH:fes00270 fes01230 fes01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:fes00290 fes00770 fes01210 fes01230 fes01100 fes01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:fes00290 fes01230 fes01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:fes00290 fes01210 fes01230 fes01100 fes01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:fes00280 fes01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:fes00300 fes01230 fes01100]

Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:fes00220 fes01230 fes01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:fes00330 fes01230 fes01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:fes00340 fes01230 fes01100 fes01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:fes00400 fes01230 fes01100 fes01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:fes00400 fes01230 fes01100 fes01110]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:fes00480 fes01240 fes01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:fes00540 fes01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:fes00540 fes01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:fes00740 fes01240 fes01100 fes01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:fes00750 fes01240 fes01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:fes00760 fes01240 fes01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:fes00770 fes01240 fes01100 fes01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:fes00770 fes01240 fes01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:fes00780 fes01240 fes01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:fes00785 fes01240 fes01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:fes00790 fes00670 fes01240 fes01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:fes00790 fes01240 fes01100]
M00140 C1-unit interconversion, prokaryotes [PATH:fes00670 fes01240 fes01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:fes00860 fes01240 fes01100 fes01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:fes00130 fes01240 fes01100 fes01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:fes00130 fes01240 fes01100 fes01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:fes00900 fes01100 fes01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:fes00900 fes01100 fes01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00718 Multidrug resistance, efflux pump MexAB-OprM

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity