KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:panx00010 panx01200 panx01230 panx01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:panx00010 panx00020 panx01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:panx00010 panx00020 panx00620 panx00785 panx01200 panx01210 panx01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:panx00020 panx01200 panx01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:panx00020 panx01200 panx01210 panx01230 panx01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:panx00020 panx01200 panx01210 panx01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:panx00030 panx01200 panx01230 panx01100 panx01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:panx00030 panx00230 panx01200 panx01230 panx01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:panx00030 panx01200 panx01100 panx01120]

Other carbohydrate metabolism
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:panx00520 panx01250 panx01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:panx00520 panx01250 panx01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:panx00521 panx00523 panx00541 panx01250 panx01100 panx01110]
M00012 Glyoxylate cycle [PATH:panx00630 panx01200 panx01100 panx01110]
M00982 Methylcitrate cycle [PATH:panx00640 panx00020 panx01200 panx01100 panx01120]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:panx00910 panx01310 panx01100 panx01120]

Sulfur metabolism
M00595 Sulfur oxidation, SOX system, thiosulfate => sulfate [PATH:panx00920 panx01100 panx01120]
M00985 Sulfide oxidation, sulfide => sulfur [PATH:panx00920 panx01100 panx01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:panx00190 panx01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:panx00190 panx01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:panx00190 panx01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:panx00190 panx01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:panx00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:panx00190 panx01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:panx00190 panx01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:panx00061 panx01212 panx01100]
M00083 Fatty acid biosynthesis, elongation [PATH:panx00061 panx01212 panx01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:panx00061 panx00071 panx01212 panx01100]
M00087 beta-Oxidation [PATH:panx00071 panx01212 panx01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:panx00564 panx01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:panx00230 panx01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:panx00230 panx01232 panx01240 panx01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:panx00230 panx01232 panx01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:panx00230 panx00240 panx01232 panx01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:panx00230 panx01232 panx01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:panx00230 panx01232 panx01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:panx00240 panx01232 panx01240 panx01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:panx00240 panx01232 panx01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:panx00260 panx00680 panx01200 panx01230 panx01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:panx00260 panx01230 panx01100 panx01110]
M00621 Glycine cleavage system [PATH:panx00260 panx00630 panx00670 panx00785 panx01200 panx01100]

Cysteine and methionine metabolism
Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:panx00290 panx00770 panx01210 panx01230 panx01100 panx01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:panx00290 panx01230 panx01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:panx00290 panx01210 panx01230 panx01100 panx01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:panx00300 panx01230 panx01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:panx00220 panx01210 panx01230 panx01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:panx00220 panx01230 panx01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:panx00330 panx01230 panx01100]
M00970 Proline degradation, proline => glutamate [PATH:panx00330 panx01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:panx00330 panx01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:panx00340 panx01230 panx01100 panx01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:panx00340 panx01100]

Aromatic amino acid metabolism
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:panx00400 panx01230 panx01100 panx01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:panx00400 panx01230 panx01100 panx01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:panx00400 panx01230 panx01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:panx00350 panx01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:panx00480 panx01240 panx01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:panx00540 panx01250 panx01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:panx00540 panx01250 panx01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:panx00760 panx01240 panx01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:panx00770 panx01240 panx01100 panx01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:panx00770 panx01240 panx01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:panx00780 panx01240 panx01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:panx00785 panx01240 panx01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:panx00790 panx00670 panx01240 panx01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:panx00790 panx01240 panx01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:panx00790 panx01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:panx00860 panx01240 panx01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:panx00130 panx01240 panx01100 panx01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:panx00362 panx00622 panx01220 panx01100 panx01120]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:panx00362 panx01220 panx01100 panx01120]
M00638 Salicylate degradation, salicylate => gentisate [PATH:panx00626 panx01100 panx01120]
M00623 Phthalate degradation, phthalate => protocatechuate [PATH:panx00624 panx01220 panx01100 panx01120]
M00545 Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA [PATH:panx00360 panx01220 panx01100 panx01120]

Gene set
Pathogenicity
Drug resistance
M00851 Carbapenem resistance [PATH:panx01501]

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation