KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:ppav00010 ppav01200 ppav01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:ppav00010 ppav01200 ppav01230 ppav01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:ppav00010 ppav00020 ppav01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:ppav00010 ppav00020 ppav00620 ppav01200 ppav01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:ppav00020 ppav01200 ppav01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:ppav00020 ppav01200 ppav01210 ppav01230 ppav01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:ppav00020 ppav01200 ppav01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:ppav00030 ppav01200 ppav01100 ppav01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:ppav00030 ppav01200 ppav01100 ppav01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:ppav00030 ppav01200 ppav01230 ppav01100 ppav01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:ppav00030 ppav00230 ppav01200 ppav01230 ppav01100]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:ppav00040 ppav00030 ppav01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:ppav00040 ppav00030 ppav01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:ppav00052 ppav01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:ppav00052 ppav01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:ppav00500 ppav01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:ppav00500 ppav01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:ppav00520 ppav01250 ppav01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:ppav00520 ppav00052 ppav01250 ppav01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:ppav00520 ppav01250 ppav01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:ppav00520 ppav01100]
M00012 Glyoxylate cycle [PATH:ppav00630 ppav01200 ppav01100 ppav01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:ppav00620 ppav01200 ppav01100 ppav01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:ppav00430 ppav00620 ppav01200 ppav01100 ppav01120]

Methane metabolism
Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:ppav00910 ppav01100 ppav01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:ppav00910 ppav01100 ppav01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:ppav00920 ppav01100 ppav01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:ppav00190]
M00150 Fumarate reductase, prokaryotes [PATH:ppav00190]
M00153 Cytochrome bd ubiquinol oxidase [PATH:ppav00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:ppav00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:ppav00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:ppav00061 ppav01212 ppav01100]
M00083 Fatty acid biosynthesis, elongation [PATH:ppav00061 ppav01212 ppav01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:ppav00061 ppav00071 ppav01212 ppav01100]
M00087 beta-Oxidation [PATH:ppav00071 ppav01212 ppav01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:ppav00564 ppav01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ppav00230 ppav01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ppav00230 ppav01232 ppav01240 ppav01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ppav00230 ppav01232 ppav01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ppav00230 ppav00240 ppav01232 ppav01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:ppav00240 ppav01240 ppav01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:ppav00240 ppav01232 ppav01240 ppav01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:ppav00240 ppav01232 ppav01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:ppav00260 ppav00680 ppav01200 ppav01230 ppav01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:ppav00260 ppav01230 ppav01100 ppav01110]
M00621 Glycine cleavage system [PATH:ppav00260 ppav00630 ppav01200 ppav01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:ppav00260 ppav01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:ppav00270 ppav00920 ppav01200 ppav01230 ppav01100 ppav01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:ppav00270 ppav01230 ppav01100]
M00034 Methionine salvage pathway [PATH:ppav00270 ppav01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:ppav00290 ppav00770 ppav01210 ppav01230 ppav01100 ppav01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:ppav00290 ppav01230 ppav01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:ppav00290 ppav01210 ppav01230 ppav01100 ppav01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:ppav00300 ppav01230 ppav01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:ppav00220 ppav01210 ppav01230 ppav01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:ppav00220 ppav01230 ppav01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:ppav00330 ppav01230 ppav01100]
M00970 Proline degradation, proline => glutamate [PATH:ppav00330 ppav01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:ppav00340 ppav01230 ppav01100 ppav01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:ppav00400 ppav01230 ppav01100 ppav01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:ppav00400 ppav01230 ppav01100 ppav01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:ppav00400 ppav01230 ppav01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:ppav00480 ppav01240 ppav01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:ppav00540 ppav01100]
M00063 CMP-KDO biosynthesis [PATH:ppav00540 ppav01250 ppav01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:ppav00540 ppav01250 ppav01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:ppav00730 ppav01240 ppav01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:ppav00730 ppav01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:ppav00740 ppav01240 ppav01100 ppav01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:ppav00750 ppav01240 ppav01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:ppav00760 ppav01240 ppav01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:ppav00770 ppav01240 ppav01100 ppav01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:ppav00770 ppav01240 ppav01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:ppav00780 ppav01240 ppav01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:ppav00780 ppav01240 ppav01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:ppav00785 ppav01240 ppav01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:ppav00790 ppav00670 ppav01240 ppav01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:ppav00790 ppav01240 ppav01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:ppav00860 ppav01240 ppav01100 ppav01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:ppav00860 ppav01240 ppav01100 ppav01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:ppav00130 ppav01240 ppav01100 ppav01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:ppav00130 ppav01240 ppav01100 ppav01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:ppav00900 ppav01100 ppav01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:ppav00900 ppav01100 ppav01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:ppav00521 ppav00523 ppav00541 ppav01250 ppav01100 ppav01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
M00675 Carbapenem-3-carboxylate biosynthesis, pyrroline-5-carboxylate + malonyl-CoA => carbapenem-3-carboxylate [PATH:ppav00332 ppav01100 ppav01110]

Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation
M00616 Sulfate-sulfur assimilation