KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:pph00010 pph01200 pph01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:pph00010 pph01200 pph01230 pph01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:pph00010 pph00020 pph01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:pph00010 pph00020 pph00620 pph00785 pph01200 pph01210 pph01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:pph00020 pph01200 pph01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:pph00020 pph01200 pph01210 pph01230 pph01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:pph00020 pph01200 pph01210 pph01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:pph00030 pph01200 pph01100 pph01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose-6P => ribulose-5P [PATH:pph00030 pph01200 pph01100 pph01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose-6P => ribose-5P [PATH:pph00030 pph01200 pph01230 pph01100 pph01120]
M00005 PRPP biosynthesis, ribose-5P => PRPP [PATH:pph00030 pph00230 pph01200 pph01230 pph01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:pph00030 pph01200 pph01100 pph01120]

Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH:pph00040 pph01100]
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde-3P [PATH:pph00040 pph00030 pph01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde-3P [PATH:pph00040 pph00030 pph01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:pph00052 pph01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:pph00052 pph01100]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:pph00040 pph00053 pph01240 pph01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:pph00500 pph01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:pph00500 pph01100]
M00565 Trehalose biosynthesis, D-glucose-1P => trehalose [PATH:pph00500 pph01100 pph01110]
M00012 Glyoxylate cycle [PATH:pph00630 pph01200 pph01100 pph01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:pph00280 pph00630 pph00640 pph01200 pph01100]
M00982 Methylcitrate cycle [PATH:pph00640 pph00020 pph01200 pph01100 pph01120]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:pph00562 pph01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:pph00562 pph01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:pph00562 pph01100]

Energy metabolism
Carbon fixation
M00165 Reductive pentose phosphate cycle (Calvin cycle) [PATH:pph00710 pph01200 pph01100 pph01120]
M00168 CAM (Crassulacean acid metabolism), dark [PATH:pph00620 pph00710 pph01200 pph01100 pph01120]
M00169 CAM (Crassulacean acid metabolism), light [PATH:pph00620 pph00710 pph01200 pph01100 pph01120]
M00173 Reductive citrate cycle (Arnon-Buchanan cycle) [PATH:pph00720 pph01200 pph01100 pph01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:pph00430 pph00620 pph00720 pph01200 pph01100 pph01120]

Methane metabolism
Nitrogen metabolism
M00175 Nitrogen fixation, nitrogen => ammonia [PATH:pph00910 pph01100 pph01120]
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:pph00910 pph01100 pph01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:pph00910 pph01100 pph01120]
M00529 Denitrification, nitrate => nitrogen [PATH:pph00910 pph01100 pph01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:pph00920 pph01320 pph01100 pph01120]
M00595 Sulfur oxidation, SOX system, thiosulfate => sulfate [PATH:pph00920 pph01320 pph01100 pph01120]
M00985 Sulfide oxidation, sulfide => sulfur [PATH:pph00920 pph01320 pph01100 pph01120]

Photosynthesis
M00598 Anoxygenic photosystem I

ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:pph00190 pph01100]
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:pph00190 pph01100]
M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:pph00190 pph01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:pph00190 pph01100]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:pph00190 pph01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:pph00190 pph01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:pph00190 pph01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:pph00190 pph01100]
M00417 Cytochrome o ubiquinol oxidase [PATH:pph00190 pph01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH:pph00190 pph01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:pph00190 pph01100]
M00160 V-type ATPase, eukaryotes [PATH:pph00190 pph01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:pph00061 pph01212 pph01100]
M00083 Fatty acid biosynthesis, elongation [PATH:pph00061 pph01212 pph01100]
M00873 Fatty acid biosynthesis in mitochondria, animals [PATH:pph00061 pph01212 pph01100]
M00085 Fatty acid elongation in mitochondria [PATH:pph01212 pph01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:pph01212 pph01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:pph00061 pph00071 pph01212 pph01100]
M00087 beta-Oxidation [PATH:pph00071 pph01212 pph01100]
M00861 beta-Oxidation, peroxisome, VLCFA [PATH:pph01212 pph01100]

Sterol biosynthesis
M00101 Cholesterol biosynthesis, FPP => cholesterol [PATH:pph01100]
M00103 Cholecalciferol biosynthesis [PATH:pph01100]
M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate [PATH:pph01100]
M00862 beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA [PATH:pph01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH:pph01100]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH:pph01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH:pph01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH:pph01100]
M00977 C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone [PATH:pph01100]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:pph00561 pph01100]
M00098 Acylglycerol degradation [PATH:pph00561 pph01100]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:pph00564 pph01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:pph00564 pph01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:pph00564 pph01100]
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:pph00564 pph01100]
M00094 Ceramide biosynthesis [PATH:pph00600 pph01100]
M00066 Lactosylceramide biosynthesis [PATH:pph00600 pph01100]
M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:pph00600 pph01100]
M00099 Sphingosine biosynthesis [PATH:pph00600 pph01100]
M00100 Sphingosine degradation [PATH:pph00600 pph01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pph00230 pph01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pph00230 pph01232 pph01240 pph01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pph00230 pph01232 pph01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pph00230 pph00240 pph01232 pph01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:pph00230 pph01232 pph01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:pph00230 pph01232 pph01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:pph00240 pph01240 pph01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:pph00240 pph01232 pph01240 pph01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:pph00240 pph01232 pph01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:pph00240 pph00410 pph00770 pph01100]
M00939 Pyrimidine degradation, uracil => 3-hydroxypropanoate [PATH:pph00240 pph01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:pph00260 pph00680 pph01200 pph01230 pph01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:pph00260 pph01230 pph01100 pph01110]
M00621 Glycine cleavage system [PATH:pph00260 pph00630 pph00670 pph00785 pph01200 pph01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:pph00260 pph00670 pph01100]
M00974 Betaine metabolism, animals, betaine => glycine [PATH:pph00260 pph00670 pph01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:pph00260 pph01210 pph01230 pph01100 pph01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:pph00270 pph00920 pph01320 pph01200 pph01230 pph01100 pph01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:pph00260 pph00270 pph00670 pph01230 pph01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:pph00270 pph01230 pph01100]
M00034 Methionine salvage pathway [PATH:pph00270 pph01100]
M00035 Methionine degradation [PATH:pph00270 pph00670 pph01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:pph00290 pph00770 pph01210 pph01230 pph01100 pph01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:pph00290 pph01230 pph01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:pph00290 pph01210 pph01230 pph01100 pph01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:pph00280 pph01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:pph00300 pph01230 pph01100]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:pph00300 pph01230 pph01100 pph01110]
M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:pph00310 pph01210 pph01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:pph00220 pph01210 pph01230 pph01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:pph00220 pph01230 pph01100]
M00029 Urea cycle [PATH:pph00220 pph01230 pph01100]
M00978 Ornithine-ammonia cycle [PATH:pph00220 pph01100 pph01110]
M00015 Proline biosynthesis, glutamate => proline [PATH:pph00330 pph01230 pph01100]
M00970 Proline degradation, proline => glutamate [PATH:pph00330 pph01100]
M00972 Proline metabolism [PATH:pph00330 pph01100]
M00047 Creatine pathway [PATH:pph00330 pph00260 pph01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:pph00330 pph01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:pph00330 pph01100]
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:pph00330 pph01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:pph00330 pph01100]
M00136 GABA biosynthesis, prokaryotes, putrescine => GABA [PATH:pph00330 pph01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:pph00340 pph01230 pph01100 pph01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:pph00340 pph01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:pph00400 pph01230 pph01100 pph01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:pph00400 pph01230 pph01100 pph01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:pph00400 pph01230 pph01100 pph01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:pph00400 pph01230 pph01100]
M00040 Tyrosine biosynthesis, chorismate => arogenate => tyrosine [PATH:pph00400 pph01230 pph01100 pph01110]
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:pph00350 pph01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:pph00350 pph01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:pph00350 pph01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:pph00380 pph01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:pph00250 pph00650 pph01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:pph00480 pph01240 pph01100]
M00948 Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate [PATH:pph00470 pph01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00892 UDP-GlcNAc biosynthesis, eukaryotes, Fru-6P => UDP-GlcNAc [PATH:pph00520 pph01250 pph01100]
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:pph00520 pph01250 pph01100]
M01003 UDP-GlcNAc biosynthesis, GlcNAc => UDP-GlcNAc [PATH:pph00520 pph01250 pph01100]
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH:pph00520 pph01250 pph01100 pph01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:pph00520 pph01250 pph01100]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:pph00520 pph01250 pph01100]
M01004 UDP-Galf biosynthesis, UDP-Glc => UDP-Galf [PATH:pph00520 pph00052 pph01250 pph01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:pph00520 pph00053 pph01250 pph01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:pph00520 pph00052 pph01250 pph01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:pph00520 pph00051 pph01250 pph01100]
M01015 GDP-Man biosynthesis, Man => GDP-Man [PATH:pph00520 pph00051 pph01250 pph01100]
M01001 GDP-L-Fuc biosynthesis, L-Fuc => GDP-L-Fuc [PATH:pph00520 pph01250 pph01100]
M00923 UDP-L-FucNAc biosynthesis, UDP-GlcNAc => UDP-L-FucNAc [PATH:pph00541 pph01250 pph01100]
M01009 UDP-QuiNAc biosynthesis, UDP-GlcNAc => UDP-QuiNAc [PATH:pph00541 pph01250 pph01100]
M00063 CMP-KDO biosynthesis, ribulose-5P => CMP-KDO [PATH:pph00541 pph01250 pph01100]
M00955 CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc [PATH:pph00541 pph01250 pph01100]
M01014 UDP-ManNAcA biosynthesis, UDP-GlcNAc => UDP-ManNAcA [PATH:pph00541 pph01250 pph01100]
M00064 ADP-LDmanHep biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:pph00541 pph01250 pph01100]
M00761 Und-P-alpha-L-Ara4N biosynthesis, UDP-Glc => UDP-L-Ara4FN => Und-P-alpha-L-Ara4N [PATH:pph00541 pph01250 pph01100]
M00793 dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha [PATH:pph00521 pph00523 pph00541 pph01250 pph01100 pph01110]
M01025 dTDP-D-Fuc4NAc biosynthesis, Glc-1P => dTDP-D-Fuc4NAc [PATH:pph00541 pph01250 pph01100]
M01016 GDP-L-Fuc biosynthesis, GDP-Man => GDP-L-Fuc [PATH:pph00541 pph00051 pph01250 pph01100]
M01017 GDP-L-Col biosynthesis, GDP-Man => GDP-L-Col [PATH:pph00541 pph01250 pph01100]
M01019 GDP-6-deoxy-Tal biosynthesis, GDP-Man => GDP-6-deoxy-Tal [PATH:pph00541 pph00051 pph01250 pph01100]

Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:pph01100]
M00072 N-glycosylation by oligosaccharyltransferase [PATH:pph01100]
M00073 N-glycan precursor trimming [PATH:pph01100]
M00075 N-glycan biosynthesis, complex type [PATH:pph01100]
M00872 O-glycan biosynthesis, mannose type (core M3) [PATH:pph01100]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH:pph01100]
M00983 GPI-anchor remodeling [PATH:pph01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:pph01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:pph01100]
M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer [PATH:pph01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:pph01100]

Glycosaminoglycan metabolism
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH:pph01100]
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:pph01100]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:pph01100]
M00076 Dermatan sulfate degradation [PATH:pph01100]
M00077 Chondroitin sulfate degradation [PATH:pph01100]
M00078 Heparan sulfate degradation [PATH:pph01100]
M00079 Keratan sulfate degradation [PATH:pph01100]

Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:pph00540 pph01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:pph00730 pph01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:pph00740 pph01240 pph01100 pph01110]
M00124 Pyridoxal phosphate biosynthesis, erythrose-4P => pyridoxal-P [PATH:pph00750 pph01240 pph01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:pph00760 pph01240 pph01100]
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:pph00380 pph00760 pph01240 pph01100]
M00622 Nicotinate degradation, nicotinate => fumarate [PATH:pph00760 pph01100 pph01120]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:pph00770 pph01240 pph01100 pph01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:pph00770 pph01240 pph01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:pph00780 pph01240 pph01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:pph00780 pph01240 pph01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:pph00785 pph01240 pph01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:pph00785 pph01240 pph01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:pph00785 pph01240 pph01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:pph00790 pph00670 pph01240 pph01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:pph00790 pph01240 pph01100]
M00843 L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4 [PATH:pph00790 pph01240 pph01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:pph00790 pph01240 pph01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:pph00790 pph01100]
M00140 C1-unit interconversion, prokaryotes [PATH:pph00670 pph01240 pph01100]
M00141 C1-unit interconversion, eukaryotes [PATH:pph00670 pph01240 pph01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:pph00860 pph01240 pph01100 pph01110]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:pph00860 pph01240 pph01100 pph01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:pph00860 pph01240 pph01100 pph01110]
M00925 Cobalamin biosynthesis, aerobic, uroporphyrinogen III => precorrin 2 => cobyrinate a,c-diamide [PATH:pph00860 pph01240 pph01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:pph00860 pph01240 pph01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:pph00130 pph01240 pph01100 pph01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:pph00130 pph01240 pph01100 pph01110]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinone [PATH:pph00130 pph01240 pph01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:pph00130 pph01240 pph01100 pph01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:pph00900 pph01100 pph01110]
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:pph00900 pph01100 pph01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:pph00900 pph01100 pph01110]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:pph00900 pph01100 pph01110]

Terpenoid biosynthesis
M00097 Lycopene biosynthesis, geranylgeranyl-PP => lycopene [PATH:pph00906 pph01100 pph01110]
M01045 Zeaxanthin biosynthesis, lycopene => beta-carotene => zeaxanthin [PATH:pph00906 pph01100 pph01110]

Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Biosynthesis of other compounds
Xenobiotics biodegradation
Aromatics degradation
M00548 Benzene degradation, benzene => catechol [PATH:pph01100 pph01120]
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol [PATH:pph01100 pph01120]
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate [PATH:pph01100 pph01120]
M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA [PATH:pph01100 pph01120]

Gene set
Pathogenicity
Drug resistance
M00639 Multidrug resistance, efflux pump MexCD-OprJ
M00642 Multidrug resistance, efflux pump MexJK-OprM
M00649 Multidrug resistance, efflux pump AdeABC [PATH:pph01501]

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00614 Anoxygenic photosynthesis in green sulfur bacteria
M00615 Nitrate assimilation
M00616 Sulfate-sulfur assimilation