KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:pvl00010 pvl01200 pvl01230 pvl01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:pvl00010 pvl00020 pvl01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:pvl00010 pvl00020 pvl00620 pvl00785 pvl01200 pvl01210 pvl01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:pvl00020 pvl01200 pvl01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:pvl00020 pvl01200 pvl01210 pvl01230 pvl01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:pvl00020 pvl01200 pvl01210 pvl01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:pvl00030 pvl01200 pvl01100 pvl01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:pvl00030 pvl01200 pvl01100 pvl01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:pvl00030 pvl01200 pvl01230 pvl01100 pvl01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:pvl00030 pvl00230 pvl01200 pvl01230 pvl01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:pvl00030 pvl01200 pvl01100 pvl01120]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:pvl00052 pvl01100]
M00012 Glyoxylate cycle [PATH:pvl00630 pvl01200 pvl01100 pvl01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:pvl00620 pvl00710 pvl01200 pvl01100 pvl01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:pvl00430 pvl00620 pvl00720 pvl01200 pvl01100 pvl01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:pvl00910 pvl01310 pvl01100 pvl01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:pvl00920 pvl01320 pvl01100 pvl01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:pvl00190 pvl01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:pvl00190 pvl01100]
M00150 Fumarate reductase, prokaryotes [PATH:pvl00190 pvl01100]
M00417 Cytochrome o ubiquinol oxidase [PATH:pvl00190 pvl01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:pvl00190 pvl01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:pvl00061 pvl01212 pvl01100]
M00083 Fatty acid biosynthesis, elongation [PATH:pvl00061 pvl01212 pvl01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:pvl00061 pvl00071 pvl01212 pvl01100]
M00087 beta-Oxidation [PATH:pvl00071 pvl01212 pvl01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:pvl00564 pvl01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pvl00230 pvl01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pvl00230 pvl01232 pvl01240 pvl01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pvl00230 pvl01232 pvl01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pvl00230 pvl00240 pvl01232 pvl01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:pvl00240 pvl01240 pvl01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:pvl00240 pvl01232 pvl01240 pvl01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:pvl00240 pvl01232 pvl01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:pvl00260 pvl00680 pvl01200 pvl01230 pvl01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:pvl00260 pvl01230 pvl01100 pvl01110]
M00621 Glycine cleavage system [PATH:pvl00260 pvl00630 pvl00670 pvl00785 pvl01200 pvl01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:pvl00260 pvl00670 pvl01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:pvl00270 pvl00920 pvl01320 pvl01200 pvl01230 pvl01100 pvl01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:pvl00270 pvl01230 pvl01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:pvl00290 pvl00770 pvl01210 pvl01230 pvl01100 pvl01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:pvl00290 pvl01230 pvl01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:pvl00290 pvl01210 pvl01230 pvl01100 pvl01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:pvl00300 pvl01230 pvl01100]
M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine [PATH:pvl00300 pvl01230 pvl01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:pvl00220 pvl01210 pvl01230 pvl01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:pvl00220 pvl01230 pvl01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:pvl00330 pvl01230 pvl01100]
M00970 Proline degradation, proline => glutamate [PATH:pvl00330 pvl01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:pvl00340 pvl01230 pvl01100 pvl01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:pvl00400 pvl01230 pvl01100 pvl01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:pvl00400 pvl01230 pvl01100 pvl01110]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:pvl00480 pvl01240 pvl01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:pvl00520 pvl01250 pvl01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:pvl00520]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:pvl00520 pvl00053]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:pvl00520 pvl00052 pvl01250 pvl01100]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:pvl00541 pvl01250 pvl01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:pvl00541 pvl01250 pvl01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:pvl00541 pvl01100]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:pvl00540 pvl01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:pvl00730 pvl01240 pvl01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:pvl00740 pvl01240 pvl01100 pvl01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:pvl00750 pvl01240 pvl01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:pvl00780 pvl01240 pvl01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:pvl00780 pvl01240 pvl01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:pvl00785 pvl01240 pvl01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:pvl00790 pvl01240 pvl01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:pvl00790 pvl01100]
M00140 C1-unit interconversion, prokaryotes [PATH:pvl00670 pvl01240 pvl01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:pvl00860 pvl01240 pvl01100 pvl01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:pvl00860 pvl01240 pvl01100 pvl01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:pvl00130 pvl01240 pvl01100 pvl01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:pvl00130 pvl01240 pvl01100 pvl01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:pvl00130 pvl01240 pvl01100 pvl01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:pvl00900 pvl01100 pvl01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:pvl00900 pvl01100 pvl01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation