KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:rphi00010 rphi01200 rphi01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:rphi00010 rphi01200 rphi01230 rphi01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:rphi00010 rphi00020 rphi01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:rphi00020 rphi01200 rphi01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:rphi00020 rphi01200 rphi01210 rphi01230 rphi01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:rphi00020 rphi01200 rphi01210 rphi01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:rphi00030 rphi01200 rphi01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:rphi00030 rphi01200 rphi01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:rphi00030 rphi01200 rphi01230 rphi01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:rphi00030 rphi00230 rphi01200 rphi01230 rphi01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:rphi00052 rphi01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:rphi00500 rphi01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:rphi00500 rphi01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:rphi00280 rphi00630 rphi00640 rphi01200 rphi01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:rphi00562 rphi01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:rphi00562 rphi01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:rphi00562 rphi01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:rphi00190 rphi01100]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:rphi00190 rphi01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:rphi00190 rphi01100]
M00160 V-type ATPase, eukaryotes [PATH:rphi00190 rphi01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:rphi00061 rphi01212 rphi01100]
M00083 Fatty acid biosynthesis, elongation [PATH:rphi00061 rphi01212 rphi01100]
M00085 Fatty acid elongation in mitochondria [PATH:rphi00062 rphi01212 rphi01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:rphi00062 rphi01040 rphi01212 rphi01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:rphi00061 rphi00071 rphi01212 rphi01100]
M00087 beta-Oxidation [PATH:rphi00071 rphi01212 rphi01100]
M00861 beta-Oxidation, peroxisome, VLCFA [PATH:rphi01040 rphi01212 rphi01100]

Sterol biosynthesis
M00103 Cholecalciferol biosynthesis [PATH:rphi00100 rphi01100]
M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate [PATH:rphi01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH:rphi01100]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:rphi00561 rphi01100]
M00098 Acylglycerol degradation [PATH:rphi00561 rphi01100]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:rphi00564 rphi01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:rphi00564 rphi01100]
M00094 Ceramide biosynthesis [PATH:rphi00600 rphi01100]
M00099 Sphingosine biosynthesis [PATH:rphi00600 rphi01100]
M00100 Sphingosine degradation [PATH:rphi00600 rphi01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rphi00230 rphi01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rphi00230 rphi01232 rphi01240 rphi01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rphi00230 rphi01232 rphi01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rphi00230 rphi00240 rphi01232 rphi01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:rphi00230 rphi01232 rphi01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:rphi00230 rphi01232 rphi01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:rphi00240 rphi01240 rphi01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:rphi00240 rphi01232 rphi01240 rphi01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:rphi00240 rphi01232 rphi01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:rphi00240 rphi00410 rphi00770 rphi01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:rphi00260 rphi01200 rphi01230 rphi01100]
M00621 Glycine cleavage system [PATH:rphi00260 rphi00630 rphi00670 rphi00785 rphi01200 rphi01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:rphi00260 rphi00670 rphi01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:rphi00260 rphi00270 rphi00670 rphi01230 rphi01100]
M00034 Methionine salvage pathway [PATH:rphi00270 rphi01100]
M00035 Methionine degradation [PATH:rphi00270 rphi00670 rphi01100]

Branched-chain amino acid metabolism
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:rphi00280 rphi01100]

Lysine metabolism
M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:rphi00310 rphi01210 rphi01100]

Arginine and proline metabolism
M00015 Proline biosynthesis, glutamate => proline [PATH:rphi00330 rphi01230 rphi01100]
M00970 Proline degradation, proline => glutamate [PATH:rphi00330 rphi01100]
M00972 Proline metabolism [PATH:rphi00330 rphi01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:rphi00330 rphi01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:rphi00330 rphi01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:rphi00340 rphi01100]

Aromatic amino acid metabolism
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:rphi00350 rphi01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:rphi00380 rphi01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:rphi00250 rphi00650 rphi01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:rphi00480 rphi01240 rphi01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00892 UDP-GlcNAc biosynthesis, eukaryotes, Fru-6P => UDP-GlcNAc [PATH:rphi00520 rphi01250 rphi01100]
M01003 UDP-GlcNAc biosynthesis, GlcNAc => UDP-GlcNAc [PATH:rphi00520]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:rphi00520 rphi01250 rphi01100]
M01004 UDP-Galf biosynthesis, UDP-Glc => UDP-Galf [PATH:rphi00520 rphi00052]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:rphi00520 rphi00052 rphi01250 rphi01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:rphi00520]
M01001 GDP-L-Fuc biosynthesis, L-Fuc => GDP-L-Fuc [PATH:rphi00520]

Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:rphi00510 rphi01100]
M00073 N-glycan precursor trimming [PATH:rphi00510 rphi01100]
M00983 GPI-anchor remodeling [PATH:rphi00563 rphi01100]

Glycosaminoglycan metabolism
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH:rphi00532 rphi00534 rphi01100]
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:rphi00532 rphi01100]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:rphi00534 rphi01100]
M00076 Dermatan sulfate degradation [PATH:rphi00531 rphi01100]
M00077 Chondroitin sulfate degradation [PATH:rphi00531 rphi01100]
M00078 Heparan sulfate degradation [PATH:rphi00531 rphi01100]
M00079 Keratan sulfate degradation [PATH:rphi00531 rphi01100]

Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:rphi00380 rphi00760 rphi01240 rphi01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:rphi00770 rphi01240 rphi01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:rphi00785 rphi01240 rphi01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:rphi00785 rphi01240 rphi01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:rphi00790 rphi01240 rphi01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:rphi00790 rphi01240 rphi01100]
M00141 C1-unit interconversion, eukaryotes [PATH:rphi00670 rphi01240 rphi01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:rphi00860 rphi01240 rphi01100]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinone [PATH:rphi00130 rphi01240 rphi01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:rphi00900 rphi01100]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:rphi00900 rphi01100]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity