KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:rvc00010 rvc01200 rvc01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:rvc00010 rvc01200 rvc01230 rvc01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:rvc00010 rvc00020 rvc01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:rvc00010 rvc00020 rvc00620 rvc00785 rvc01200 rvc01210 rvc01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:rvc00020 rvc01200 rvc01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:rvc00020 rvc01200 rvc01210 rvc01230 rvc01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:rvc00020 rvc01200 rvc01210 rvc01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:rvc00030 rvc01200 rvc01100 rvc01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:rvc00030 rvc01200 rvc01100 rvc01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:rvc00030 rvc01200 rvc01230 rvc01100 rvc01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:rvc00030 rvc00230 rvc01200 rvc01230 rvc01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:rvc00030 rvc01200 rvc01100 rvc01120]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:rvc00040 rvc00030 rvc01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:rvc00040 rvc00030 rvc01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:rvc00052 rvc01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:rvc00053 rvc01100 rvc01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:rvc00500 rvc01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:rvc00500 rvc01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:rvc00500 rvc01100 rvc01110]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:rvc00520 rvc01250 rvc01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:rvc00520 rvc00052 rvc01250 rvc01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:rvc00520 rvc01250 rvc01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:rvc00520 rvc01100]
M00012 Glyoxylate cycle [PATH:rvc00630 rvc01200 rvc01100 rvc01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:rvc00620 rvc00710 rvc01200 rvc01100 rvc01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:rvc00430 rvc00620 rvc00720 rvc01200 rvc01100 rvc01120]

Methane metabolism
Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:rvc00910 rvc01100 rvc01120]
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:rvc00910 rvc01100 rvc01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:rvc00920 rvc01100 rvc01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:rvc00190 rvc01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:rvc00190 rvc01100]
M00150 Fumarate reductase, prokaryotes [PATH:rvc00190 rvc01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:rvc00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:rvc00190 rvc01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:rvc00190 rvc01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:rvc00061 rvc01212 rvc01100]
M00083 Fatty acid biosynthesis, elongation [PATH:rvc00061 rvc01212 rvc01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:rvc00061 rvc00071 rvc01212 rvc01100]
M00087 beta-Oxidation [PATH:rvc00071 rvc01212 rvc01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:rvc00564 rvc01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rvc00230 rvc01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rvc00230 rvc01232 rvc01240 rvc01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rvc00230 rvc01232 rvc01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rvc00230 rvc00240 rvc01232 rvc01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:rvc00230 rvc01232 rvc01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:rvc00230 rvc01232 rvc01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:rvc00240 rvc01240 rvc01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:rvc00240 rvc01232 rvc01240 rvc01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:rvc00240 rvc01232 rvc01100]
M00939 Pyrimidine degradation, uracil => 3-hydroxypropanoate [PATH:rvc00240 rvc01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:rvc00260 rvc00680 rvc01200 rvc01230 rvc01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:rvc00260 rvc01230 rvc01100 rvc01110]
M00621 Glycine cleavage system [PATH:rvc00260 rvc00630 rvc00785 rvc01200 rvc01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:rvc00260 rvc01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:rvc00270 rvc00920 rvc01200 rvc01230 rvc01100 rvc01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:rvc00270 rvc01230 rvc01100]
M00034 Methionine salvage pathway [PATH:rvc00270 rvc01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:rvc00290 rvc00770 rvc01210 rvc01230 rvc01100 rvc01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:rvc00290 rvc01230 rvc01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:rvc00290 rvc01210 rvc01230 rvc01100 rvc01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:rvc00300 rvc01230 rvc01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:rvc00220 rvc01210 rvc01230 rvc01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:rvc00220 rvc01230 rvc01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:rvc00330 rvc01230 rvc01100]
M00970 Proline degradation, proline => glutamate [PATH:rvc00330 rvc01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:rvc00330 rvc01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:rvc00340 rvc01230 rvc01100 rvc01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:rvc00340 rvc01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:rvc00400 rvc01230 rvc01100 rvc01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:rvc00400 rvc01230 rvc01100 rvc01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:rvc00400 rvc01230 rvc01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:rvc00480 rvc01240 rvc01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:rvc00540 rvc01100]
M00063 CMP-KDO biosynthesis [PATH:rvc00540 rvc01250 rvc01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:rvc00540 rvc01250 rvc01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:rvc00730 rvc01240 rvc01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:rvc00730 rvc01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:rvc00740 rvc01240 rvc01100 rvc01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:rvc00750 rvc01240 rvc01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:rvc00760 rvc01240 rvc01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:rvc00770 rvc01240 rvc01100 rvc01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:rvc00770 rvc01240 rvc01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:rvc00780 rvc01240 rvc01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:rvc00785 rvc01240 rvc01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:rvc00790 rvc00670 rvc01240 rvc01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:rvc00790 rvc01240 rvc01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:rvc00860 rvc01240 rvc01100 rvc01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:rvc00860 rvc01240 rvc01100 rvc01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:rvc00130 rvc01240 rvc01100 rvc01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:rvc00130 rvc01240 rvc01100 rvc01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:rvc00900 rvc01100 rvc01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:rvc00900 rvc01100 rvc01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation
M00616 Sulfate-sulfur assimilation