KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:sens00010 sens01200 sens01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:sens00010 sens01200 sens01230 sens01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:sens00010 sens00020 sens01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sens00010 sens00020 sens00620 sens00785 sens01200 sens01210 sens01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:sens00020 sens01200 sens01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:sens00020 sens01200 sens01210 sens01230 sens01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:sens00020 sens01200 sens01210 sens01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:sens00030 sens01200 sens01100 sens01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:sens00030 sens01200 sens01100 sens01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:sens00030 sens01200 sens01230 sens01100 sens01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:sens00030 sens00230 sens01200 sens01230 sens01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:sens00030 sens01200 sens01100 sens01120]

Other carbohydrate metabolism
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:sens00040 sens00030 sens01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:sens00052 sens01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:sens00053 sens01100 sens01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:sens00500 sens01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:sens00500 sens01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:sens00500 sens01100 sens01110]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:sens00520 sens01250 sens01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:sens00520 sens00052 sens01250 sens01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:sens00520 sens01250 sens01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:sens00520 sens01100]
M00012 Glyoxylate cycle [PATH:sens00630 sens01200 sens01100 sens01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:sens00620 sens00710 sens01200 sens01100 sens01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:sens00430 sens00620 sens00720 sens01200 sens01100 sens01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:sens00910 sens01100 sens01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:sens00920 sens01100 sens01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:sens00190 sens01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:sens00190 sens01100]
M00150 Fumarate reductase, prokaryotes [PATH:sens00190 sens01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:sens00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:sens00190 sens01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:sens00190 sens01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:sens00061 sens01212 sens01100]
M00083 Fatty acid biosynthesis, elongation [PATH:sens00061 sens01212 sens01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:sens00061 sens00071 sens01212 sens01100]
M00087 beta-Oxidation [PATH:sens00071 sens01212 sens01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:sens00564 sens01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sens00230 sens01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sens00230 sens01232 sens01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sens00230 sens00240 sens01232 sens01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:sens00240 sens01240 sens01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:sens00240 sens01232 sens01240 sens01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:sens00240 sens01232 sens01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:sens00260 sens00680 sens01200 sens01230 sens01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:sens00260 sens01230 sens01100 sens01110]
M00621 Glycine cleavage system [PATH:sens00260 sens00630 sens00785 sens01200 sens01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:sens00270 sens00920 sens01200 sens01230 sens01100 sens01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:sens00270 sens01230 sens01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:sens00290 sens00770 sens01210 sens01230 sens01100 sens01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:sens00290 sens01230 sens01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:sens00290 sens01210 sens01230 sens01100 sens01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:sens00300 sens01230 sens01100]
M00956 Lysine degradation, bacteria, L-lysine => succinate [PATH:sens00310 sens01100 sens01120]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:sens00220 sens01210 sens01230 sens01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:sens00220 sens01230 sens01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:sens00330 sens01230 sens01100]
M00970 Proline degradation, proline => glutamate [PATH:sens00330 sens01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:sens00330 sens01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:sens00330 sens01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:sens00340 sens01230 sens01100 sens01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:sens00340 sens01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:sens00400 sens01230 sens01100 sens01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:sens00400 sens01230 sens01100 sens01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:sens00400 sens01230 sens01100 sens01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:sens00400 sens01230 sens01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:sens00350 sens01220 sens01100 sens01120]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:sens00480 sens01240 sens01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:sens00540 sens01100]
M00063 CMP-KDO biosynthesis [PATH:sens00540 sens01250 sens01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:sens00540 sens01250 sens01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:sens00730 sens01240 sens01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:sens00730 sens01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:sens00740 sens01240 sens01100 sens01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:sens00750 sens01240 sens01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:sens00760 sens01240 sens01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:sens00770 sens01240 sens01100 sens01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:sens00770 sens01240 sens01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:sens00780 sens01240 sens01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:sens00780 sens01240 sens01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:sens00785 sens01240 sens01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:sens00790 sens01240 sens01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:sens00860 sens01240 sens01100 sens01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:sens00860 sens01240 sens01100 sens01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:sens00860 sens01240 sens01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:sens00860 sens01240 sens01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:sens00130 sens01240 sens01100 sens01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:sens00130 sens01240 sens01100 sens01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:sens00900 sens01100 sens01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:sens00900 sens01100 sens01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:sens00521 sens00523 sens00541 sens01250 sens01100 sens01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00744 Cationic antimicrobial peptide (CAMP) resistance, protease PgtE
M00696 Multidrug resistance, efflux pump AcrEF-TolC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation