KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:setr00010 setr01200 setr01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:setr00010 setr01200 setr01230 setr01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:setr00010 setr00020 setr01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:setr00010 setr00020 setr00620 setr00785 setr01200 setr01210 setr01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:setr00020 setr01200 setr01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:setr00020 setr01200 setr01210 setr01230 setr01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:setr00020 setr01200 setr01210 setr01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:setr00030 setr01200 setr01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:setr00030 setr01200 setr01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:setr00030 setr01200 setr01230 setr01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:setr00030 setr00230 setr01200 setr01230 setr01100]

Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH:setr00040 setr01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:setr00052 setr01100]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:setr00040 setr00053 setr01240 setr01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:setr00500 setr01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:setr00500 setr01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:setr00280 setr00630 setr00640 setr01200 setr01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:setr00562 setr01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:setr00562 setr01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:setr00562 setr01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:setr00190 setr01100]
M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:setr00190 setr01100]
M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex [PATH:setr00190 setr01100]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:setr00190 setr01100]
M00160 V-type ATPase, eukaryotes [PATH:setr00190 setr01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:setr00061 setr01212 setr01100]
M00083 Fatty acid biosynthesis, elongation [PATH:setr00061 setr01212 setr01100]
M00873 Fatty acid biosynthesis in mitochondria, animals [PATH:setr00061 setr01212 setr01100]
M00085 Fatty acid elongation in mitochondria [PATH:setr00062 setr01212 setr01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:setr00062 setr01040 setr01212 setr01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:setr00061 setr00071 setr01212 setr01100]
M00087 beta-Oxidation [PATH:setr00071 setr01212 setr01100]
M00861 beta-Oxidation, peroxisome, VLCFA [PATH:setr01040 setr01212 setr01100]

Sterol biosynthesis
M00101 Cholesterol biosynthesis, FPP => cholesterol [PATH:setr00100 setr01100]
M00103 Cholecalciferol biosynthesis [PATH:setr00100 setr01100]
M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate [PATH:setr00120 setr01100]
M00862 beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA [PATH:setr00120 setr01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH:setr00140 setr01100]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH:setr00140 setr01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH:setr00140 setr01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH:setr00140 setr01100]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:setr00561 setr01100]
M00098 Acylglycerol degradation [PATH:setr00561 setr01100]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:setr00564 setr01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:setr00564 setr01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:setr00564 setr01100]
M00094 Ceramide biosynthesis [PATH:setr00600 setr01100]
M00066 Lactosylceramide biosynthesis [PATH:setr00600 setr01100]
M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:setr00600 setr00565 setr01100]
M00099 Sphingosine biosynthesis [PATH:setr00600 setr01100]
M00100 Sphingosine degradation [PATH:setr00600 setr01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:setr00230 setr01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:setr00230 setr01232 setr01240 setr01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:setr00230 setr01232 setr01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:setr00230 setr00240 setr01232 setr01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:setr00230 setr01232 setr01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:setr00230 setr01232 setr01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:setr00240 setr01240 setr01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:setr00240 setr01232 setr01240 setr01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:setr00240 setr01232 setr01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:setr00240 setr00410 setr00770 setr01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:setr00260 setr01200 setr01230 setr01100]
M00621 Glycine cleavage system [PATH:setr00260 setr00630 setr00670 setr00785 setr01200 setr01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:setr00260 setr00670 setr01100]
M00974 Betaine metabolism, animals, betaine => glycine [PATH:setr00260 setr00670 setr01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:setr00260 setr00270 setr00670 setr01230 setr01100]
M00034 Methionine salvage pathway [PATH:setr00270 setr01100]
M00035 Methionine degradation [PATH:setr00270 setr00670 setr01100]

Branched-chain amino acid metabolism
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:setr00280 setr01100]

Lysine metabolism
M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:setr00310 setr01210 setr01100]

Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:setr00220 setr01230 setr01100]
M00029 Urea cycle [PATH:setr00220 setr01230 setr01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:setr00330 setr01230 setr01100]
M00970 Proline degradation, proline => glutamate [PATH:setr00330 setr01100]
M00972 Proline metabolism [PATH:setr00330 setr01100]
M00047 Creatine pathway [PATH:setr00330 setr00260 setr01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:setr00330 setr01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:setr00330 setr01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:setr00340 setr01100]

Aromatic amino acid metabolism
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:setr00350 setr01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:setr00350 setr01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:setr00350 setr01100]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH:setr00380 setr01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:setr00380 setr01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:setr00250 setr00650 setr01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:setr00480 setr01240 setr01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00892 UDP-GlcNAc biosynthesis, eukaryotes, Fru-6P => UDP-GlcNAc [PATH:setr00520 setr01250 setr01100]
M01003 UDP-GlcNAc biosynthesis, GlcNAc => UDP-GlcNAc [PATH:setr00520]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:setr00520 setr01250 setr01100]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:setr00520 setr00052 setr01250 setr01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:setr00520]
M01001 GDP-L-Fuc biosynthesis, L-Fuc => GDP-L-Fuc [PATH:setr00520]
M00955 CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc [PATH:setr00541 setr01250]

Glycan biosynthesis
M00072 N-glycosylation by oligosaccharyltransferase [PATH:setr00510 setr00513 setr01100]
M00073 N-glycan precursor trimming [PATH:setr00510 setr01100]
M00075 N-glycan biosynthesis, complex type [PATH:setr00510 setr01100]
M00872 O-glycan biosynthesis, mannose type (core M3) [PATH:setr00515 setr01100]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH:setr00563 setr01100]
M00983 GPI-anchor remodeling [PATH:setr00563 setr01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:setr00601 setr01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:setr00601 setr01100]
M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer [PATH:setr00603 setr01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:setr00604 setr01100]

Glycosaminoglycan metabolism
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH:setr00532 setr00534 setr01100]
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:setr00532 setr01100]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:setr00534 setr01100]
M00076 Dermatan sulfate degradation [PATH:setr00531 setr01100]
M00077 Chondroitin sulfate degradation [PATH:setr00531 setr01100]
M00078 Heparan sulfate degradation [PATH:setr00531 setr01100]
M00079 Keratan sulfate degradation [PATH:setr00531 setr01100]

Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:setr00380 setr00760 setr01240 setr01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:setr00770 setr01240 setr01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:setr00785 setr01240 setr01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:setr00785 setr01240 setr01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:setr00790 setr01240 setr01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:setr00790 setr01240 setr01100]
M00141 C1-unit interconversion, eukaryotes [PATH:setr00670 setr01240 setr01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:setr00860 setr01240 setr01100]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinone [PATH:setr00130 setr01240 setr01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:setr00900 setr01100]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:setr00900 setr01100]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity