KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:setu00010 setu01200 setu01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:setu00010 setu01200 setu01230 setu01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:setu00010 setu00020 setu01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:setu00010 setu00020 setu00620 setu00785 setu01200 setu01210 setu01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:setu00020 setu01200 setu01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:setu00020 setu01200 setu01210 setu01230 setu01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:setu00020 setu01200 setu01210 setu01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:setu00030 setu01200 setu01100 setu01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:setu00030 setu01200 setu01100 setu01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:setu00030 setu01200 setu01230 setu01100 setu01120]
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH:setu00030 setu01200 setu01230 setu01100 setu01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:setu00030 setu00230 setu01200 setu01230 setu01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:setu00030 setu01200 setu01100 setu01120]

Other carbohydrate metabolism
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:setu00040 setu00030 setu01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:setu00052 setu01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:setu00052 setu01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:setu00053 setu01100 setu01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:setu00500 setu01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:setu00500 setu01100]
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose [PATH:setu00500 setu01100 setu01110]
M00012 Glyoxylate cycle [PATH:setu00630 setu01200 setu01100 setu01110]
M00982 Methylcitrate cycle [PATH:setu00640 setu00020 setu01200 setu01100 setu01120]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:setu00620 setu00710 setu01200 setu01100 setu01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:setu00430 setu00620 setu00720 setu01200 setu01100 setu01120]

Methane metabolism
M00345 Formaldehyde assimilation, ribulose monophosphate pathway [PATH:setu00030 setu00680 setu01200 setu01230 setu01100 setu01120]

Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:setu00910 setu01310 setu01100 setu01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:setu00920 setu01320 setu01100 setu01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:setu00190 setu01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:setu00190 setu01100]
M00150 Fumarate reductase, prokaryotes [PATH:setu00190 setu01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:setu00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:setu00190 setu01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:setu00190 setu01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:setu00061 setu01212 setu01100]
M00083 Fatty acid biosynthesis, elongation [PATH:setu00061 setu01212 setu01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:setu00061 setu00071 setu01212 setu01100]
M00087 beta-Oxidation [PATH:setu00071 setu01212 setu01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:setu00564 setu01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:setu00230 setu01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:setu00230 setu01232 setu01240 setu01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:setu00230 setu01232 setu01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:setu00230 setu00240 setu01232 setu01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:setu00240 setu01240 setu01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:setu00240 setu01232 setu01240 setu01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:setu00240 setu01232 setu01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:setu00260 setu00680 setu01200 setu01230 setu01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:setu00260 setu01230 setu01100 setu01110]
M00621 Glycine cleavage system [PATH:setu00260 setu00630 setu00670 setu00785 setu01200 setu01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:setu00270 setu00920 setu01320 setu01200 setu01230 setu01100 setu01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:setu00270 setu01230 setu01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:setu00290 setu00770 setu01210 setu01230 setu01100 setu01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:setu00290 setu01230 setu01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:setu00290 setu01210 setu01230 setu01100 setu01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:setu00300 setu01230 setu01100]
M00956 Lysine degradation, bacteria, L-lysine => succinate [PATH:setu00310 setu01100 setu01120]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:setu00220 setu01210 setu01230 setu01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:setu00220 setu01230 setu01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:setu00330 setu01230 setu01100]
M00970 Proline degradation, proline => glutamate [PATH:setu00330 setu01100]
M00879 Arginine succinyltransferase pathway, arginine => glutamate [PATH:setu00330 setu01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:setu00330 setu01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:setu00340 setu01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:setu00400 setu01230 setu01100 setu01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:setu00400 setu01230 setu01100 setu01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:setu00400 setu01230 setu01100 setu01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:setu00400 setu01230 setu01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH:setu00350 setu01220 setu01100 setu01120]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:setu00480 setu01240 setu01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:setu00520 setu01250 setu01100]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:setu00520]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:setu00520 setu01250 setu01100]
M01004 UDP-Galf biosynthesis, UDP-Glc => UDP-Galf [PATH:setu00520 setu00052]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:setu00520 setu00052 setu01250 setu01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:setu00520]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:setu00541 setu01250 setu01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis, sedoheptulose-7P => ADP-LDmanHep [PATH:setu00541 setu01250 setu01100]
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N [PATH:setu00541 setu01100]
M00793 dTDP-L-rhamnose biosynthesis, glucose-1P => dTDP-L-Rha [PATH:setu00521 setu00523 setu00541 setu01250 setu01100 setu01110]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:setu00540 setu01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:setu00730 setu01240 setu01100]
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:setu00730 setu01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:setu00740 setu01240 setu01100 setu01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:setu00750 setu01240 setu01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:setu00760 setu01240 setu01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:setu00770 setu01240 setu01100 setu01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:setu00770 setu01240 setu01100]
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP [PATH:setu00780 setu01240 setu01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:setu00780 setu01240 setu01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:setu00785 setu01240 setu01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:setu00790 setu00670 setu01240 setu01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:setu00790 setu01240 setu01100]
M00988 PreQ1 biosynthesis, GTP => 7-Aminomethyl-7-deazaguanine [PATH:setu00790 setu01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:setu00860 setu01240 setu01100 setu01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:setu00860 setu01240 setu01100 setu01110]
M00924 Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide [PATH:setu00860 setu01240 setu01100]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:setu00860 setu01240 setu01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:setu00130 setu01240 setu01100 setu01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:setu00130 setu01240 setu01100 setu01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:setu00130 setu01240 setu01100 setu01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:setu00900 setu01100 setu01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:setu00900 setu01100 setu01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00744 Cationic antimicrobial peptide (CAMP) resistance, protease PgtE
M00696 Multidrug resistance, efflux pump AcrEF-TolC

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation