KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:sgb00010 sgb01200 sgb01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:sgb00010 sgb01200 sgb01230 sgb01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:sgb00010 sgb00020 sgb01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sgb00010 sgb00020 sgb00620 sgb00785 sgb01200 sgb01210 sgb01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:sgb00020 sgb01200 sgb01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:sgb00020 sgb01200 sgb01210 sgb01230 sgb01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:sgb00020 sgb01200 sgb01210 sgb01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:sgb00030 sgb01200 sgb01100 sgb01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:sgb00030 sgb01200 sgb01100 sgb01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:sgb00030 sgb01200 sgb01230 sgb01100 sgb01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:sgb00030 sgb00230 sgb01200 sgb01230 sgb01100]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:sgb00052 sgb01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:sgb00500 sgb01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:sgb00520 sgb01250 sgb01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:sgb00520 sgb00052 sgb01250 sgb01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:sgb00520 sgb01250 sgb01100]
M00012 Glyoxylate cycle [PATH:sgb00630 sgb01200 sgb01100 sgb01110]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sgb00280 sgb00630 sgb00640 sgb01200 sgb01100]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:sgb00620 sgb00710 sgb01200 sgb01100 sgb01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:sgb00430 sgb00620 sgb00720 sgb01200 sgb01100 sgb01120]

Methane metabolism
Nitrogen metabolism
Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:sgb00920 sgb01100 sgb01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:sgb00190 sgb01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:sgb00190 sgb01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:sgb00190 sgb01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:sgb00190 sgb01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:sgb00190 sgb01100]

Lipid metabolism
Fatty acid metabolism
M00083 Fatty acid biosynthesis, elongation [PATH:sgb00061 sgb01212 sgb01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:sgb00061 sgb00071 sgb01212 sgb01100]
M00087 beta-Oxidation [PATH:sgb00071 sgb01212 sgb01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:sgb00564 sgb01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sgb00230 sgb01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sgb00230 sgb01232 sgb01240 sgb01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sgb00230 sgb01232 sgb01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sgb00230 sgb00240 sgb01232 sgb01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:sgb00230 sgb01232 sgb01100]
M00546 Purine degradation, xanthine => urea [PATH:sgb00230 sgb01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:sgb00240 sgb01232 sgb01240 sgb01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:sgb00240 sgb01232 sgb01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:sgb00260 sgb00680 sgb01200 sgb01230 sgb01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:sgb00260 sgb01230 sgb01100 sgb01110]
M00621 Glycine cleavage system [PATH:sgb00260 sgb00630 sgb00785 sgb01200 sgb01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:sgb00260 sgb01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:sgb00260 sgb01210 sgb01230 sgb01100 sgb01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:sgb00270 sgb00920 sgb01200 sgb01230 sgb01100 sgb01110]
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:sgb00260 sgb00270 sgb01230 sgb01100]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:sgb00270 sgb01230 sgb01100]
M00035 Methionine degradation [PATH:sgb00270 sgb01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:sgb00290 sgb00770 sgb01210 sgb01230 sgb01100 sgb01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:sgb00290 sgb01230 sgb01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:sgb00290 sgb01210 sgb01230 sgb01100 sgb01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:sgb00300 sgb01230 sgb01100]
M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine [PATH:sgb00300 sgb01230 sgb01100]
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:sgb00300 sgb01230 sgb01100 sgb01110]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:sgb00220 sgb01210 sgb01230 sgb01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:sgb00220 sgb01230 sgb01100]
M00978 Ornithine-ammonia cycle [PATH:sgb00220 sgb01100 sgb01110]
M00015 Proline biosynthesis, glutamate => proline [PATH:sgb00330 sgb01230 sgb01100]
M00970 Proline degradation, proline => glutamate [PATH:sgb00330 sgb01100]
M00972 Proline metabolism [PATH:sgb00330 sgb01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:sgb00340 sgb01230 sgb01100 sgb01110]

Aromatic amino acid metabolism
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:sgb00400 sgb01230 sgb01100 sgb01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:sgb00400 sgb01230 sgb01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:sgb00250 sgb00650 sgb01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:sgb01250 sgb01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:sgb01250 sgb01100]

Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:sgb00730 sgb01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:sgb00740 sgb01240 sgb01100 sgb01110]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:sgb00750 sgb01240 sgb01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:sgb00760 sgb01240 sgb01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:sgb00770 sgb01240 sgb01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:sgb00780 sgb01240 sgb01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:sgb00785 sgb01240 sgb01100]
M00140 C1-unit interconversion, prokaryotes [PATH:sgb00670 sgb01240 sgb01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:sgb00860 sgb01240 sgb01100 sgb01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:sgb00860 sgb01240 sgb01100 sgb01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:sgb00860 sgb01240 sgb01100]
M00847 Heme biosynthesis, archaea, siroheme => heme [PATH:sgb00860 sgb01240 sgb01100 sgb01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:sgb00860 sgb01240 sgb01100]
M00930 Menaquinone biosynthesis, futalosine pathway [PATH:sgb00130 sgb01240 sgb01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway [PATH:sgb00900 sgb01100 sgb01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:sgb00900 sgb01100 sgb01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
M00824 9-membered enediyne core biosynthesis, malonyl-CoA => 3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-ACP => 9-membered enediyne core [PATH:sgb01059 sgb01100 sgb01110]
M00826 C-1027 benzoxazolinate moiety biosynthesis, chorismate => benzoxazolinyl-CoA [PATH:sgb01059 sgb01100 sgb01110]
M00827 C-1027 beta-amino acid moiety biosynthesis, tyrosine => 3-chloro-4,5-dihydroxy-beta-phenylalanyl-PCP [PATH:sgb01059 sgb01100 sgb01110]

Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:sgb00521 sgb00523 sgb00541 sgb01250 sgb01100 sgb01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity