KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:srx00010 srx01200 srx01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:srx00010 srx01200 srx01230 srx01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:srx00010 srx00020 srx01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:srx00010 srx00020 srx00620 srx00785 srx01200 srx01210 srx01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:srx00020 srx01200 srx01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:srx00020 srx01200 srx01210 srx01230 srx01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:srx00020 srx01200 srx01210 srx01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:srx00030 srx01200 srx01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:srx00030 srx01200 srx01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:srx00030 srx01200 srx01230 srx01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:srx00030 srx00230 srx01200 srx01230 srx01100]

Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH:srx00040 srx01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:srx00052 srx01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:srx00500 srx01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:srx00500 srx01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:srx00520 srx01250 srx01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:srx00520 srx00052 srx01250 srx01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH:srx00520 srx01250 srx01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:srx00280 srx00630 srx00640 srx01200 srx01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:srx00562 srx01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:srx00562 srx01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:srx00562 srx01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00142 NADH:ubiquinone oxidoreductase, mitochondria [PATH:srx00190 srx01100]
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria [PATH:srx00190 srx01100]
M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex [PATH:srx00190 srx01100]
M00148 Succinate dehydrogenase (ubiquinone) [PATH:srx00190 srx01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:srx00190 srx01100]
M00152 Cytochrome bc1 complex [PATH:srx00190 srx01100]
M00158 F-type ATPase, eukaryotes [PATH:srx00190 srx01100]
M00160 V-type ATPase, eukaryotes [PATH:srx00190 srx01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:srx00061 srx01212 srx01100]
M00083 Fatty acid biosynthesis, elongation [PATH:srx00061 srx01212 srx01100]
M00873 Fatty acid biosynthesis in mitochondria, animals [PATH:srx00061 srx01212 srx01100]
M00085 Fatty acid elongation in mitochondria [PATH:srx00062 srx01212 srx01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:srx00062 srx01040 srx01212 srx01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:srx00061 srx00071 srx01212 srx01100]
M00087 beta-Oxidation [PATH:srx00071 srx01212 srx01100]

Sterol biosynthesis
M00101 Cholesterol biosynthesis, FPP => cholesterol [PATH:srx00100 srx01100]
M00103 Cholecalciferol biosynthesis [PATH:srx00100 srx01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH:srx00140 srx01100]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH:srx00140 srx01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH:srx00140 srx01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH:srx00140 srx01100]

Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:srx00561 srx01100]
M00098 Acylglycerol degradation [PATH:srx00561 srx01100]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:srx00564 srx01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:srx00564 srx01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:srx00564 srx01100]
M00094 Ceramide biosynthesis [PATH:srx00600 srx01100]
M00066 Lactosylceramide biosynthesis [PATH:srx00600 srx01100]
M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid [PATH:srx00600 srx00565 srx01100]
M00099 Sphingosine biosynthesis [PATH:srx00600 srx01100]
M00100 Sphingosine degradation [PATH:srx00600 srx01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:srx00230 srx01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:srx00230 srx01232 srx01240 srx01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:srx00230 srx01232 srx01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:srx00230 srx00240 srx01232 srx01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:srx00230 srx01232 srx01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:srx00230 srx01232 srx01100]
M00546 Purine degradation, xanthine => urea [PATH:srx00230 srx01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:srx00240 srx01240 srx01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:srx00240 srx01232 srx01240 srx01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:srx00240 srx00410 srx00770 srx01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:srx00260 srx01200 srx01230 srx01100]
M00621 Glycine cleavage system [PATH:srx00260 srx00630 srx00785 srx01200 srx01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:srx00260 srx01100]
M00974 Betaine metabolism, animals, betaine => glycine [PATH:srx00260 srx01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:srx00260 srx00270 srx01230 srx01100]
M00034 Methionine salvage pathway [PATH:srx00270 srx01100]
M00035 Methionine degradation [PATH:srx00270 srx01100]

Branched-chain amino acid metabolism
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:srx00280 srx01100]

Lysine metabolism
M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA [PATH:srx00310 srx01210 srx01100]

Arginine and proline metabolism
M00015 Proline biosynthesis, glutamate => proline [PATH:srx00330 srx01230 srx01100]
M00970 Proline degradation, proline => glutamate [PATH:srx00330 srx01100]
M00972 Proline metabolism [PATH:srx00330 srx01100]
M00047 Creatine pathway [PATH:srx00330 srx00260 srx01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:srx00330 srx01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:srx00330 srx01100]

Histidine metabolism
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:srx00340 srx01100]

Aromatic amino acid metabolism
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH:srx00350 srx01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH:srx00350 srx01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:srx00350 srx01100]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH:srx00380 srx01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:srx00380 srx01100]

Other amino acid metabolism
M00027 GABA (gamma-Aminobutyrate) shunt [PATH:srx00250 srx00650 srx01100]
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:srx00480 srx01240 srx01100]

Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:srx00510 srx01100]
M00073 N-glycan precursor trimming [PATH:srx00510 srx01100]
M00075 N-glycan biosynthesis, complex type [PATH:srx00510 srx01100]
M00872 O-glycan biosynthesis, mannose type (core M3) [PATH:srx00515 srx01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH:srx00601 srx01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH:srx00601 srx01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH:srx00604 srx01100]

Glycosaminoglycan metabolism
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH:srx00532 srx00534 srx01100]
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:srx00532 srx01100]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:srx00534 srx01100]
M00076 Dermatan sulfate degradation [PATH:srx00531 srx01100]
M00077 Chondroitin sulfate degradation [PATH:srx00531 srx01100]
M00078 Heparan sulfate degradation [PATH:srx00531 srx01100]
M00079 Keratan sulfate degradation [PATH:srx00531 srx01100]

Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:srx00770 srx01240 srx01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:srx00785 srx01240 srx01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:srx00785 srx01240 srx01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:srx00790 srx01240 srx01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:srx00790 srx01240 srx01100]
M00141 C1-unit interconversion, eukaryotes [PATH:srx00670 srx01240 srx01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:srx00860 srx01240 srx01100]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH:srx00130 srx01240 srx01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:srx00900 srx01100]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:srx00900 srx01100]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity