KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:tvd00010 tvd01200 tvd01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:tvd00010 tvd01200 tvd01230 tvd01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:tvd00010 tvd00020 tvd01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:tvd00010 tvd00020 tvd00620 tvd00785 tvd01200 tvd01210 tvd01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:tvd00020 tvd01200 tvd01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:tvd00020 tvd01200 tvd01210 tvd01230 tvd01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:tvd00020 tvd01200 tvd01210 tvd01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:tvd00030 tvd01200 tvd01100 tvd01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:tvd00030 tvd01200 tvd01100 tvd01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:tvd00030 tvd01200 tvd01230 tvd01100 tvd01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:tvd00030 tvd00230 tvd01200 tvd01230 tvd01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:tvd00030 tvd01200 tvd01100 tvd01120]

Other carbohydrate metabolism
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:tvd00052 tvd01100]
M00012 Glyoxylate cycle [PATH:tvd00630 tvd01200 tvd01100 tvd01110]
M00982 Methylcitrate cycle [PATH:tvd00640 tvd00020 tvd01200 tvd01100 tvd01120]

Energy metabolism
Carbon fixation
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:tvd00430 tvd00620 tvd00720 tvd01200 tvd01100 tvd01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:tvd00910 tvd01310 tvd01100 tvd01120]
M00529 Denitrification, nitrate => nitrogen [PATH:tvd00910 tvd01310 tvd01100 tvd01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:tvd00920 tvd01320 tvd01100 tvd01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:tvd00190 tvd01100]
M00149 Succinate dehydrogenase, prokaryotes [PATH:tvd00190 tvd01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:tvd00190 tvd01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:tvd00190 tvd01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH:tvd00190 tvd01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:tvd00190 tvd01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:tvd00061 tvd01212 tvd01100]
M00083 Fatty acid biosynthesis, elongation [PATH:tvd00061 tvd01212 tvd01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:tvd00061 tvd00071 tvd01212 tvd01100]
M00087 beta-Oxidation [PATH:tvd00071 tvd01212 tvd01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:tvd00564 tvd01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:tvd00230 tvd01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:tvd00230 tvd01232 tvd01240 tvd01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:tvd00230 tvd01232 tvd01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:tvd00230 tvd00240 tvd01232 tvd01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:tvd00230 tvd01232 tvd01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:tvd00230 tvd01232 tvd01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:tvd00240 tvd01232 tvd01240 tvd01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:tvd00260 tvd00680 tvd01200 tvd01230 tvd01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:tvd00260 tvd01230 tvd01100 tvd01110]
M00621 Glycine cleavage system [PATH:tvd00260 tvd00630 tvd00670 tvd00785 tvd01200 tvd01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:tvd00260 tvd00670 tvd01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:tvd00270 tvd00920 tvd01320 tvd01200 tvd01230 tvd01100 tvd01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:tvd00270 tvd01230 tvd01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:tvd00290 tvd00770 tvd01210 tvd01230 tvd01100 tvd01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:tvd00290 tvd01230 tvd01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:tvd00290 tvd01210 tvd01230 tvd01100 tvd01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:tvd00280 tvd01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:tvd00300 tvd01230 tvd01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:tvd00220 tvd01210 tvd01230 tvd01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:tvd00220 tvd01230 tvd01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:tvd00330 tvd01230 tvd01100]
M00970 Proline degradation, proline => glutamate [PATH:tvd00330 tvd01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:tvd00340 tvd01230 tvd01100 tvd01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:tvd00340 tvd01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:tvd00400 tvd01230 tvd01100 tvd01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:tvd00400 tvd01230 tvd01100 tvd01110]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:tvd00380 tvd01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:tvd00480 tvd01240 tvd01100]

Glycan metabolism
Nucleotide sugar biosynthesis
M00909 UDP-GlcNAc biosynthesis, prokaryotes, Fru-6P => UDP-GlcNAc [PATH:tvd00520 tvd01250 tvd01100]
M00996 UDP-MurNAc biosynthesis, anhMurNAc => UDP-MurNAc [PATH:tvd00520]
M00995 UDP-MurNAc biosynthesis, Fru-6P => UDP-MurNAc [PATH:tvd00520]
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc [PATH:tvd00520 tvd01250 tvd01100]
M00999 UDP-GlcA/GalA biosynthesis, UDP-Glc => UDP-GlcA => UDP-GalA [PATH:tvd00520 tvd00053]
M00554 UDP-Gal biosynthesis, Gal => UDP-Gal [PATH:tvd00520 tvd00052 tvd01250 tvd01100]
M01000 GDP-Man biosynthesis, Fru-6P => GDP-Man [PATH:tvd00520]
M00063 CMP-3-deoxy-D-manno-octulosonate biosynthesis, ribulose-5P => CMP-KDO [PATH:tvd00541 tvd01250 tvd01100]

Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Other polysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:tvd00740 tvd01240 tvd01100 tvd01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:tvd00750 tvd01240 tvd01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:tvd00760 tvd01240 tvd01100]
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:tvd00380 tvd00760 tvd01240 tvd01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:tvd00770 tvd01240 tvd01100 tvd01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:tvd00770 tvd01240 tvd01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:tvd00780 tvd01240 tvd01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:tvd00785 tvd01240 tvd01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:tvd00790 tvd00670 tvd01240 tvd01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:tvd00790 tvd01240 tvd01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:tvd00860 tvd01240 tvd01100 tvd01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:tvd00860 tvd01240 tvd01100 tvd01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:tvd00130 tvd01240 tvd01100 tvd01110]
M00989 Ubiquinone biosynthesis, O2-independent, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:tvd00130 tvd01240 tvd01100 tvd01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity