KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:vnv00010 vnv01200 vnv01230 vnv01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:vnv00010 vnv00020 vnv01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:vnv00010 vnv00020 vnv00620 vnv01200 vnv01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:vnv00020 vnv01200 vnv01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:vnv00020 vnv01200 vnv01210 vnv01230 vnv01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:vnv00020 vnv01200 vnv01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:vnv00030 vnv01200 vnv01100 vnv01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:vnv00030 vnv01200 vnv01100 vnv01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:vnv00030 vnv01200 vnv01230 vnv01100 vnv01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:vnv00030 vnv00230 vnv01200 vnv01230 vnv01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:vnv00030 vnv01200 vnv01100 vnv01120]

Other carbohydrate metabolism
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:vnv00500 vnv01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:vnv00500 vnv01100]
M00012 Glyoxylate cycle [PATH:vnv00630 vnv01200 vnv01100 vnv01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:vnv00620 vnv01200 vnv01100 vnv01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:vnv00430 vnv00620 vnv01200 vnv01100 vnv01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:vnv00910 vnv01100 vnv01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:vnv00920 vnv01100 vnv01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:vnv00190]
M00150 Fumarate reductase, prokaryotes [PATH:vnv00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:vnv00190]
M00153 Cytochrome bd ubiquinol oxidase [PATH:vnv00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:vnv00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH:vnv00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:vnv00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:vnv00061 vnv01212 vnv01100]
M00083 Fatty acid biosynthesis, elongation [PATH:vnv00061 vnv01212 vnv01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:vnv00061 vnv00071 vnv01212 vnv01100]
M00087 beta-Oxidation [PATH:vnv00071 vnv01212 vnv01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:vnv00564 vnv01100]

Nucleotide metabolism
Purine metabolism
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:vnv00230 vnv01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:vnv00230 vnv01240 vnv01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:vnv00230 vnv01100]

Pyrimidine metabolism
M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP [PATH:vnv00240 vnv01240 vnv01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:vnv00240 vnv01240 vnv01100]
M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP => dCTP [PATH:vnv00240 vnv01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:vnv00260 vnv00680 vnv01200 vnv01230 vnv01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:vnv00260 vnv01230 vnv01100 vnv01110]
M00555 Betaine biosynthesis, choline => betaine [PATH:vnv00260 vnv01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:vnv00260 vnv01210 vnv01230 vnv01100 vnv01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:vnv00270 vnv00920 vnv01200 vnv01230 vnv01100 vnv01110]
M00017 Methionine biosynthesis, apartate => homoserine => methionine [PATH:vnv00270 vnv01230 vnv01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:vnv00290 vnv00770 vnv01210 vnv01230 vnv01100 vnv01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:vnv00290 vnv01230 vnv01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:vnv00290 vnv01210 vnv01230 vnv01100 vnv01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:vnv00300 vnv01230 vnv01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:vnv00220 vnv01210 vnv01230 vnv01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:vnv00220 vnv01230 vnv01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:vnv00330 vnv01230 vnv01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:vnv00330 vnv01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:vnv00340 vnv01230 vnv01100 vnv01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:vnv00340 vnv01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:vnv00400 vnv01230 vnv01100 vnv01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:vnv00400 vnv01230 vnv01100 vnv01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:vnv00400 vnv01230 vnv01100 vnv01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:vnv00400 vnv01230 vnv01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:vnv00350 vnv01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:vnv00480 vnv01240 vnv01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:vnv00540 vnv01100]
M00063 CMP-KDO biosynthesis [PATH:vnv00540 vnv01250 vnv01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:vnv00540 vnv01250 vnv01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:vnv00730 vnv01240 vnv01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:vnv00740 vnv01240 vnv01100 vnv01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:vnv00750 vnv01240 vnv01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:vnv00760 vnv01240 vnv01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:vnv00770 vnv01240 vnv01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:vnv00780 vnv01240 vnv01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:vnv00785 vnv01240 vnv01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:vnv00790 vnv01240 vnv01100]
M00140 C1-unit interconversion, prokaryotes [PATH:vnv00670 vnv01240 vnv01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:vnv00860 vnv01240 vnv01100 vnv01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:vnv00860 vnv01240 vnv01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:vnv00130 vnv01240 vnv01100 vnv01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:vnv00130 vnv01240 vnv01100 vnv01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity