KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:vsr00010 vsr01200 vsr01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:vsr00010 vsr01200 vsr01230 vsr01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:vsr00010 vsr00020 vsr01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:vsr00010 vsr00020 vsr00620 vsr01200 vsr01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:vsr00020 vsr01200 vsr01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:vsr00020 vsr01200 vsr01210 vsr01230 vsr01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:vsr00020 vsr01200 vsr01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:vsr00030 vsr01200 vsr01100 vsr01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:vsr00030 vsr01200 vsr01100 vsr01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:vsr00030 vsr01200 vsr01230 vsr01100 vsr01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:vsr00030 vsr00230 vsr01200 vsr01230 vsr01100]

Other carbohydrate metabolism
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH:vsr00040 vsr00030 vsr01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:vsr00040 vsr00030 vsr01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:vsr00052 vsr01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH:vsr00053 vsr01100 vsr01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:vsr00500 vsr01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:vsr00520 vsr01250 vsr01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:vsr00520 vsr00052 vsr01250 vsr01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:vsr00520 vsr01250 vsr01100]
M00012 Glyoxylate cycle [PATH:vsr00630 vsr01200 vsr01100 vsr01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:vsr00620 vsr01200 vsr01100 vsr01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:vsr00430 vsr00620 vsr01200 vsr01100 vsr01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:vsr00910 vsr01100 vsr01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:vsr00920 vsr01100 vsr01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:vsr00190]
M00150 Fumarate reductase, prokaryotes [PATH:vsr00190]
M00153 Cytochrome bd ubiquinol oxidase [PATH:vsr00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:vsr00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:vsr00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:vsr00061 vsr01212 vsr01100]
M00083 Fatty acid biosynthesis, elongation [PATH:vsr00061 vsr01212 vsr01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:vsr00061 vsr00071 vsr01212 vsr01100]
M00087 beta-Oxidation [PATH:vsr00071 vsr01212 vsr01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:vsr00564 vsr01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:vsr00230 vsr01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:vsr00230 vsr01232 vsr01240 vsr01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:vsr00230 vsr01232 vsr01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:vsr00230 vsr00240 vsr01232 vsr01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:vsr00230 vsr01232 vsr01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:vsr00230 vsr01232 vsr01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:vsr00240 vsr01240 vsr01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:vsr00240 vsr01232 vsr01240 vsr01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:vsr00260 vsr00680 vsr01200 vsr01230 vsr01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:vsr00260 vsr01230 vsr01100 vsr01110]
M00621 Glycine cleavage system [PATH:vsr00260 vsr00630 vsr01200 vsr01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:vsr00260 vsr01100]
M00033 Ectoine biosynthesis, aspartate => ectoine [PATH:vsr00260 vsr01210 vsr01230 vsr01100 vsr01120]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:vsr00270 vsr00920 vsr01200 vsr01230 vsr01100 vsr01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:vsr00270 vsr01230 vsr01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:vsr00290 vsr00770 vsr01210 vsr01230 vsr01100 vsr01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:vsr00290 vsr01230 vsr01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:vsr00290 vsr01210 vsr01230 vsr01100 vsr01110]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:vsr00300 vsr01230 vsr01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:vsr00220 vsr01210 vsr01230 vsr01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:vsr00220 vsr01230 vsr01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:vsr00330 vsr01230 vsr01100]
M00970 Proline degradation, proline => glutamate [PATH:vsr00330 vsr01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:vsr00340 vsr01230 vsr01100 vsr01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:vsr00340 vsr01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:vsr00400 vsr01230 vsr01100 vsr01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:vsr00400 vsr01230 vsr01100 vsr01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:vsr00400 vsr01230 vsr01100 vsr01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:vsr00400 vsr01230 vsr01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:vsr00480 vsr01240 vsr01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type [PATH:vsr00540 vsr01100]
M00063 CMP-KDO biosynthesis [PATH:vsr00540 vsr01250 vsr01100]
M00064 ADP-L-glycero-D-manno-heptose biosynthesis [PATH:vsr00540 vsr01250 vsr01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00127 Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP [PATH:vsr00730 vsr01240 vsr01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:vsr00740 vsr01240 vsr01100 vsr01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:vsr00750 vsr01240 vsr01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:vsr00760 vsr01240 vsr01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:vsr00770 vsr01240 vsr01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:vsr00780 vsr01240 vsr01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:vsr00785 vsr01240 vsr01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:vsr00790 vsr00670 vsr01240 vsr01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:vsr00790 vsr01240 vsr01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:vsr00860 vsr01240 vsr01100 vsr01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:vsr00860 vsr01240 vsr01100]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:vsr00130 vsr01240 vsr01100 vsr01110]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:vsr00130 vsr01240 vsr01100 vsr01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
M00675 Carbapenem-3-carboxylate biosynthesis, pyrroline-5-carboxylate + malonyl-CoA => carbapenem-3-carboxylate [PATH:vsr00332 vsr01100 vsr01110]

Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
M00837 Prodigiosin biosynthesis, L-proline => prodigiosin [PATH:vsr00333 vsr01100 vsr01110]

Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00649 Multidrug resistance, efflux pump AdeABC [PATH:vsr01501]

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity