KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:xax00010 xax01200 xax01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:xax00010 xax01200 xax01230 xax01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:xax00010 xax00020 xax00620 xax01200 xax01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:xax00020 xax01200 xax01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:xax00020 xax01200 xax01210 xax01230 xax01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:xax00020 xax01200 xax01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:xax00030 xax01200 xax01100 xax01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:xax00030 xax01200 xax01100 xax01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:xax00030 xax01200 xax01230 xax01100 xax01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:xax00030 xax00230 xax01200 xax01230 xax01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:xax00030 xax01200 xax01100 xax01120]

Other carbohydrate metabolism
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH:xax00040 xax00030 xax01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH:xax00052 xax01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:xax00520 xax01250 xax01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:xax00520 xax01250 xax01100]
M00012 Glyoxylate cycle [PATH:xax00630 xax01200 xax01100 xax01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:xax00620 xax01200 xax01100 xax01120]

Methane metabolism
Nitrogen metabolism
M00531 Assimilatory nitrate reduction, nitrate => ammonia [PATH:xax00910 xax01100 xax01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:xax00920 xax01100 xax01120]

Photosynthesis
ATP synthesis
M00144 NADH:quinone oxidoreductase, prokaryotes [PATH:xax00190]
M00149 Succinate dehydrogenase, prokaryotes [PATH:xax00190]
M00151 Cytochrome bc1 complex respiratory unit [PATH:xax00190]
M00155 Cytochrome c oxidase, prokaryotes [PATH:xax00190]
M00153 Cytochrome bd ubiquinol oxidase [PATH:xax00190]
M00417 Cytochrome o ubiquinol oxidase [PATH:xax00190]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:xax00190]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:xax00061 xax01212 xax01100]
M00083 Fatty acid biosynthesis, elongation [PATH:xax00061 xax01212 xax01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:xax00061 xax00071 xax01212 xax01100]
M00087 beta-Oxidation [PATH:xax00071 xax01212 xax01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:xax00564 xax01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:xax00230 xax01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:xax00230 xax01232 xax01240 xax01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:xax00230 xax01232 xax01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:xax00230 xax00240 xax01232 xax01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:xax00230 xax01232 xax01100]

Pyrimidine metabolism
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:xax00240 xax01232 xax01240 xax01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:xax00240 xax01232 xax01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:xax00260 xax00680 xax01200 xax01230 xax01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:xax00260 xax01230 xax01100 xax01110]
M00621 Glycine cleavage system [PATH:xax00260 xax00630 xax01200 xax01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:xax00260 xax01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:xax00260 xax00270 xax01230 xax01100]
M00034 Methionine salvage pathway [PATH:xax00270 xax01100]
M00035 Methionine degradation [PATH:xax00270 xax01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:xax00290 xax00770 xax01210 xax01230 xax01100 xax01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:xax00290 xax01230 xax01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:xax00290 xax01210 xax01230 xax01100 xax01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:xax00280 xax01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:xax00300 xax01230 xax01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:xax00220 xax01210 xax01230 xax01100]
M00845 Arginine biosynthesis, glutamate => acetylcitrulline => arginine [PATH:xax00220 xax01230 xax01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:xax00330 xax01230 xax01100]
M00970 Proline degradation, proline => glutamate [PATH:xax00330 xax01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:xax00340 xax01230 xax01100 xax01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:xax00340 xax01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:xax00400 xax01230 xax01100 xax01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:xax00400 xax01230 xax01100 xax01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH:xax00400 xax01230 xax01100 xax01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH:xax00400 xax01230 xax01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH:xax00350 xax01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:xax00480 xax01240 xax01100]
M00948 Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate [PATH:xax00470 xax01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:xax00540 xax01250 xax01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:xax00740 xax01240 xax01100 xax01110]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:xax00770 xax01240 xax01100 xax01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:xax00770 xax01240 xax01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:xax00780 xax01240 xax01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:xax00785 xax01240 xax01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:xax00790 xax00670 xax01240 xax01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:xax00790 xax01240 xax01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:xax00860 xax01240 xax01100 xax01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:xax00860 xax01240 xax01100 xax01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:xax00860 xax01240 xax01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:xax00521 xax00523 xax00541 xax01250 xax01100 xax01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00639 Multidrug resistance, efflux pump MexCD-OprJ

Plant pathogenicity
M00660 Xanthomonas spp. pathogenicity signature, T3SS and effectors

Symbiosis
Module set
Metabolic capacity
M00615 Nitrate assimilation
M00616 Sulfate-sulfur assimilation