KEGG Parkinson disease - Homo sapiens (human)
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    • nt06410 Calcium signaling
      • N01032 Mutation-inactivated PRKN to mGluR1 signaling pathway
      • N01031 Mutation-caused aberrant SNCA to VGCC-Ca2+ -apoptotic pathway
    • nt06420 Ubiquitin-proteasome system
      • N01020 Mutation-inactivated PRKN to Parkin-mediated ubiquitination
      • N01022 Mutation-inactivated PRKN to Parkin-mediated ubiquitination
      • N01024 Mutation-inactivated PRKN to Parkin-mediated ubiquitination
      • N01026 Mutation-inactivated PRKN to Parkin-mediated ubiquitination
      • N01030 Mutation-caused aberrant SNCA to 26S proteasome-mediated protein degradation
      • N01028 Mutation-inactivated UCHL1 to UCHL1-mediated hydrolysis
    • nt06412 Unfolded protein response (UPR) signaling
      • N01035 Mutation-caused aberrant SNCA to PERK-ATF4 signaling pathway
      • N01034 Mutation-caused aberrant SNCA to IRE1a-XBP1 signaling pathway
      • N01033 Mutation-caused aberrant SNCA to ATF6-mediated transcription
    • nt06421 Mitophagy
      • N01053 Mutation-inactivated PINK1 to PINK1-Parkin-mediated MFN2 degradation
      • N01054 Mutation-inactivated PRKN to PINK1-Parkin-mediated MFN2 degradation
    • nt06414 Apoptosis
      • N01051 Mutation-inactivated DJ1 to intrinsic apoptotic pathway
      • N01050 Mutation-inactivated PINK1 to intrinsic apoptotic pathway
      • N01049 Mutation-inactivated PRKN to intrinsic apoptotic pathway
      • N01048 Mutation-inactivated PINK1 to intrinsic apoptotic pathway
      • N01047 Mutation-activated LRRK2 to intrinsic apoptotic pathway
      • N01057 Mutation-inactivated DJ1 to FAS-JNK signaling patwhay
    • nt06422 Dopamine metabolism
      • N01037 Mutation-caused aberrant SNCA to L-DOPA generation
      • N01039 Mutation-inactivated PRKN to DOPAL generation
      • N01041 Mutation-caused aberrant SNCA to transport of dopamine
    • nt06418 Oxidative phosphorylation
      • N01042 Mutation-caused aberrant SNCA to electron transfer in Complex I
      • N01043 Mutation-inactivated PINK1 to electron transfer in Complex I
      • N01044 MPP+ to electron transfer in Complex I
      • N01045 Rotenone to electron transfer in Complex I
      • N01046 Maneb to electron transfer in Complex III
    • nt06419 Microtubule-based transport
      • N01055 Mutation-caused aberrant SNCA to anterograde axonal transport
    • nt06440 Transcription
      • N01058 Mutation-inactivated DJ1 to to p53-mediated transcription
      • N01059 Mutation-inactivated DJ1 to KEAP1-NRF2 signaling pathway