KEGG    Metabolic pathways - Oryzias latipes (Japanese medaka) Help
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  • Category title

  • Pathway module
    • Carbohydrate metabolism 
      • Central carbohydrate metabolism 
        • M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
        • M00002 Glycolysis, core module involving three-carbon compounds
        • M00003 Gluconeogenesis, oxaloacetate => fructose-6P
        • M00307 Pyruvate oxidation, pyruvate => acetyl-CoA
        • M00009 Citrate cycle (TCA cycle, Krebs cycle)
        • M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
        • M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
        • M00004 Pentose phosphate pathway (Pentose phosphate cycle)
        • M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
        • M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P
        • M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P
        • M00005 PRPP biosynthesis, ribose 5P => PRPP
        • M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate
        • M00308 Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P
        • M00633 Semi-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate-3P
        • M00309 Non-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate
      • Other carbohydrate metabolism 
        • M00014 Glucuronate pathway (uronate pathway)
        • M00630 D-Galacturonate degradation (fungi), D-galacturonate => glycerol
        • M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P
        • M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P
        • M00081 Pectin degradation
        • M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P
        • M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P
        • M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate
        • M00114 Ascorbate biosynthesis, plants, glucose-6P => ascorbate
        • M00550 Ascorbate degradation, ascorbate => D-xylulose-5P
        • M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch
        • M00855 Glycogen degradation, glycogen => glucose-6P
        • M00565 Trehalose biosynthesis, D-glucose 1P => trehalose
        • M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose
        • M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose
        • M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N
        • M00012 Glyoxylate cycle
        • M00373 Ethylmalonyl pathway
        • M00740 Methylaspartate cycle
        • M00532 Photorespiration
        • M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA
        • M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
        • M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
        • M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol
        • M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate
    • Energy metabolism 
      • Carbon fixation 
        • M00165 Reductive pentose phosphate cycle (Calvin cycle)
        • M00166 Reductive pentose phosphate cycle, ribulose-5P => glyceraldehyde-3P
        • M00167 Reductive pentose phosphate cycle, glyceraldehyde-3P => ribulose-5P
        • M00168 CAM (Crassulacean acid metabolism), dark
        • M00169 CAM (Crassulacean acid metabolism), light
        • M00172 C4-dicarboxylic acid cycle, NADP - malic enzyme type
        • M00171 C4-dicarboxylic acid cycle, NAD - malic enzyme type
        • M00170 C4-dicarboxylic acid cycle, phosphoenolpyruvate carboxykinase type
        • M00173 Reductive citrate cycle (Arnon-Buchanan cycle)
        • M00376 3-Hydroxypropionate bi-cycle
        • M00375 Hydroxypropionate-hydroxybutylate cycle
        • M00374 Dicarboxylate-hydroxybutyrate cycle
        • M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
        • M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate
        • M00620 Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate
      • Methane metabolism 
        • M00567 Methanogenesis, CO2 => methane
        • M00357 Methanogenesis, acetate => methane
        • M00356 Methanogenesis, methanol => methane
        • M00563 Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
        • M00358 Coenzyme M biosynthesis
        • M00608 2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
        • M00174 Methane oxidation, methanotroph, methane => formaldehyde
        • M00346 Formaldehyde assimilation, serine pathway
        • M00345 Formaldehyde assimilation, ribulose monophosphate pathway
        • M00344 Formaldehyde assimilation, xylulose monophosphate pathway
        • M00378 F420 biosynthesis
        • M00422 Acetyl-CoA pathway, CO2 => acetyl-CoA
      • Nitrogen metabolism 
        • M00175 Nitrogen fixation, nitrogen => ammonia
        • M00531 Assimilatory nitrate reduction, nitrate => ammonia
        • M00530 Dissimilatory nitrate reduction, nitrate => ammonia
        • M00529 Denitrification, nitrate => nitrogen
        • M00528 Nitrification, ammonia => nitrite
        • M00804 Complete nitrification, comammox, ammonia => nitrite => nitrate
      • Sulfur metabolism 
        • M00176 Assimilatory sulfate reduction, sulfate => H2S
        • M00596 Dissimilatory sulfate reduction, sulfate => H2S
        • M00595 Thiosulfate oxidation by SOX complex, thiosulfate => sulfate
    • Lipid metabolism 
      • Fatty acid metabolism 
        • M00082 Fatty acid biosynthesis, initiation
        • M00083 Fatty acid biosynthesis, elongation
        • M00873 Fatty acid biosynthesis in mitochondria, animals
        • M00874 Fatty acid biosynthesis in mitochondria, fungi
        • M00085 Fatty acid elongation in mitochondria
        • M00415 Fatty acid elongation in endoplasmic reticulum
        • M00086 beta-Oxidation, acyl-CoA synthesis
        • M00087 beta-Oxidation
        • M00861 beta-Oxidation, peroxisome, VLCFA
      • Sterol biosynthesis 
        • M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol
        • M00102 Ergocalciferol biosynthesis
        • M00103 Cholecalciferol biosynthesis
        • M00104 Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
        • M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate
        • M00862 beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
        • M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
        • M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
        • M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
        • M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
      • Lipid metabolism 
        • M00088 Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone
        • M00089 Triacylglycerol biosynthesis
        • M00098 Acylglycerol degradation
        • M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC
        • M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC
        • M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE
        • M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE
        • M00094 Ceramide biosynthesis
        • M00066 Lactosylceramide biosynthesis
        • M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid
        • M00099 Sphingosine biosynthesis
        • M00100 Sphingosine degradation
        • M00113 Jasmonic acid biosynthesis
    • Nucleotide metabolism 
      • Purine metabolism 
        • M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP
        • M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
        • M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP
        • M00546 Purine degradation, xanthine => urea
      • Pyrimidine metabolism 
        • M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP
        • M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
        • M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP
        • M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
    • Amino acid metabolism 
      • Serine and threonine metabolism 
        • M00020 Serine biosynthesis, glycerate-3P => serine
        • M00018 Threonine biosynthesis, aspartate => homoserine => threonine
        • M00555 Betaine biosynthesis, choline => betaine
        • M00033 Ectoine biosynthesis, aspartate => ectoine
      • Cysteine and methionine metabolism 
        • M00021 Cysteine biosynthesis, serine => cysteine
        • M00338 Cysteine biosynthesis, homocysteine + serine => cysteine
        • M00609 Cysteine biosynthesis, methionine => cysteine
        • M00017 Methionine biosynthesis, apartate => homoserine => methionine
        • M00034 Methionine salvage pathway
        • M00035 Methionine degradation
        • M00368 Ethylene biosynthesis, methionine => ethylene
      • Branched-chain amino acid metabolism 
        • M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
        • M00535 Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
        • M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
        • M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
        • M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA
      • Lysine metabolism 
        • M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
        • M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
        • M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
        • M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
        • M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
        • M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
        • M00031 Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
        • M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
      • Arginine and proline metabolism 
        • M00028 Ornithine biosynthesis, glutamate => ornithine
        • M00763 Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
        • M00844 Arginine biosynthesis, ornithine => arginine
        • M00845 Arginine biosynthesis, glutamate => acetylcitrulline => arginine
        • M00029 Urea cycle
        • M00015 Proline biosynthesis, glutamate => proline
        • M00047 Creatine pathway
      • Polyamine biosynthesis 
        • M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine
        • M00134 Polyamine biosynthesis, arginine => ornithine => putrescine
        • M00135 GABA biosynthesis, eukaryotes, putrescine => GABA
        • M00136 GABA biosynthesis, prokaryotes, putrescine => GABA
      • Histidine metabolism 
        • M00026 Histidine biosynthesis, PRPP => histidine
        • M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate
      • Aromatic amino acid metabolism 
        • M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate
        • M00023 Tryptophan biosynthesis, chorismate => tryptophan
        • M00024 Phenylalanine biosynthesis, chorismate => phenylalanine
        • M00025 Tyrosine biosynthesis, chorismate => tyrosine
        • M00040 Tyrosine biosynthesis, prephanate => pretyrosine => tyrosine
        • M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
        • M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
        • M00044 Tyrosine degradation, tyrosine => homogentisate
        • M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate
        • M00545 Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
        • M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin
        • M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
      • Other amino acid metabolism 
        • M00027 GABA (gamma-Aminobutyrate) shunt
        • M00369 Cyanogenic glycoside biosynthesis, tyrosine => dhurrin
        • M00118 Glutathione biosynthesis, glutamate => glutathione
    • Glycan metabolism 
      • Glycan biosynthesis 
        • M00055 N-glycan precursor biosynthesis
        • M00072 N-glycosylation by oligosaccharyltransferase
        • M00073 N-glycan precursor trimming
        • M00074 N-glycan biosynthesis, high-mannose type
        • M00075 N-glycan biosynthesis, complex type
        • M00056 O-glycan biosynthesis, mucin type core
        • M00872 O-glycan biosynthesis, mannose type (core M3)
        • M00065 GPI-anchor biosynthesis, core oligosaccharide
        • M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer
        • M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer
        • M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer
        • M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3
      • Glycosaminoglycan metabolism 
        • M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide
        • M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone
        • M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone
        • M00076 Dermatan sulfate degradation
        • M00077 Chondroitin sulfate degradation
        • M00078 Heparan sulfate degradation
        • M00079 Keratan sulfate degradation
      • Lipopolysaccharide metabolism 
        • M00060 KDO2-lipid A biosynthesis, Raetz pathway, LpxL-LpxM type
        • M00866 KDO2-lipid A biosynthesis, Raetz pathway, non-LpxL-LpxM type
        • M00867 KDO2-lipid A modification pathway
        • M00063 CMP-KDO biosynthesis
        • M00064 ADP-L-glycero-D-manno-heptose biosynthesis
    • Metabolism of cofactors and vitamins 
      • Cofactor and vitamin metabolism 
        • M00127 Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P
        • M00125 Riboflavin biosynthesis, GTP => riboflavin/FMN/FAD
        • M00124 Pyridoxal biosynthesis, erythrose-4P => pyridoxal-5P
        • M00115 NAD biosynthesis, aspartate => NAD
        • M00810 Nicotine degradation, pyridine pathway, nicotine => 2,6-dihydroxypyridine/succinate semialdehyde
        • M00811 Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
        • M00622 Nicotinate degradation, nicotinate => fumarate
        • M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate
        • M00120 Coenzyme A biosynthesis, pantothenate => CoA
        • M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP
        • M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin
        • M00573 Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin
        • M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin
        • M00126 Tetrahydrofolate biosynthesis, GTP => THF
        • M00840 Tetrahydrofolate biosynthesis, mediated by ribA and trpF, GTP => THF
        • M00841 Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
        • M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4
        • M00843 L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4
        • M00140 C1-unit interconversion, prokaryotes
        • M00141 C1-unit interconversion, eukaryotes
        • M00868 Heme biosynthesis, animals and fungi, glycine => heme
        • M00121 Heme biosynthesis, plants and bacteria, glutamate => heme
        • M00846 Siroheme biosynthesis, glutamate => siroheme
        • M00847 Heme biosynthesis, archaea, siroheme => heme
        • M00122 Cobalamin biosynthesis, cobinamide => cobalamin
        • M00836 Coenzyme F430 biosynthesis, sirohydrochlorin => coenzyme F430
        • M00117 Ubiquinone biosynthesis, prokaryotes, chorismate => ubiquinone
        • M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone
        • M00116 Menaquinone biosynthesis, chorismate => menaquinol
        • M00112 Tocopherol/tocotorienol biosynthesis
    • Biosynthesis of terpenoids and polyketides 
      • Terpenoid backbone biosynthesis 
        • M00095 C5 isoprenoid biosynthesis, mevalonate pathway
        • M00849 C5 isoprenoid biosynthesis, mevalonate pathway, archaea
        • M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway
        • M00364 C10-C20 isoprenoid biosynthesis, bacteria
        • M00365 C10-C20 isoprenoid biosynthesis, archaea
        • M00366 C10-C20 isoprenoid biosynthesis, plants
        • M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes
      • Other terpenoid biosynthesis 
        • M00097 beta-Carotene biosynthesis, GGAP => beta-carotene
        • M00372 Abscisic acid biosynthesis, beta-carotene => abscisic acid
        • M00371 Castasterone biosynthesis, campesterol => castasterone
      • Macrolide biosynthesis 
        • M00773 Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin
        • M00774 Erythromycin biosynthesis, propanoyl-CoA + methylmalonyl-CoA => deoxyerythronolide B => erythromycin A/B
        • M00775 Oleandomycin biosynthesis, malonyl-CoA + methylmalonyl-CoA => 8,8a-deoxyoleandolide => oleandomycin
        • M00776 Pikromycin/methymycin biosynthesis, methylmalonyl-CoA + malonyl-CoA => narbonolide/10-deoxymethynolide => pikromycin/methymycin
        • M00777 Avermectin biosynthesis, 2-methylbutanoyl-CoA/isobutyryl-CoA => 6,8a-Seco-6,8a-deoxy-5-oxoavermectin 1a/1b aglycone => avermectin A1a/B1a/A1b/B1b
      • Enediyne biosynthesis 
        • M00824 9-membered enediyne core biosynthesis, malonyl-CoA => 3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-ACP => 9-membered enediyne core
        • M00825 10-membered enediyne core biosynthesis, malonyl-CoA => 3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-ACP => 10-membered enediyne core
        • M00826 C-1027 benzoxazolinate moiety biosynthesis, chorismate => benzoxazolinyl-CoA
        • M00827 C-1027 beta-amino acid moiety biosynthesis, tyrosine => 3-chloro-4,5-dihydroxy-beta-phenylalanyl-PCP
        • M00828 Maduropeptin beta-hydroxy acid moiety biosynthesis, tyrosine => 3-(4-hydroxyphenyl)-3-oxopropanoyl-PCP
        • M00829 3,6-Dimethylsalicylyl-CoA biosynthesis, malonyl-CoA => 6-methylsalicylate => 3,6-dimethylsalicylyl-CoA
        • M00830 Neocarzinostatin naphthoate moiety biosynthesis, malonyl-CoA => 2-hydroxy-5-methyl-1-naphthoate => 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA
        • M00831 Kedarcidin 2-hydroxynaphthoate moiety biosynthesis, malonyl-CoA => 3,6,8-trihydroxy-2-naphthoate => 3-hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoyl-CoA
        • M00832 Kedarcidin 2-aza-3-chloro-beta-tyrosine moiety biosynthesis, azatyrosine => 2-aza-3-chloro-beta-tyrosyl-PCP
        • M00834 Calicheamicin orsellinate moiety biosynthesis, malonyl-CoA => orsellinate-ACP => 5-iodo-2,3-dimethoxyorsellinate-ACP
        • M00833 Calicheamicin biosynthesis, calicheamicinone => calicheamicin
      • Type II polyketide biosynthesis 
        • M00778 Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
        • M00779 Dihydrokalafungin biosynthesis, octaketide => dihydrokalafungin
        • M00780 Tetracycline/oxytetracycline biosynthesis, pretetramide => tetracycline/oxytetracycline
        • M00823 Chlortetracycline biosynthesis, pretetramide => chlortetracycline
        • M00781 Nogalavinone/aklavinone biosynthesis, deoxynogalonate/deoxyaklanonate => nogalavinone/aklavinone
        • M00782 Mithramycin biosynthesis, 4-demethylpremithramycinone => mithramycin
        • M00783 Tetracenomycin C/8-demethyltetracenomycin C biosynthesis, tetracenomycin F2 => tetracenomycin C/8-demethyltetracenomycin C
        • M00784 Elloramycin biosynthesis, 8-demethyltetracenomycin C => elloramycin A
      • Polyketide sugar unit biosynthesis 
        • M00793 dTDP-L-rhamnose biosynthesis
        • M00794 dTDP-6-deoxy-D-allose biosynthesis
        • M00795 dTDP-beta-L-noviose biosynthesis
        • M00796 dTDP-D-mycaminose biosynthesis
        • M00797 dTDP-D-desosamine biosynthesis
        • M00798 dTDP-L-mycarose biosynthesis
        • M00799 dTDP-L-oleandrose biosynthesis
        • M00800 dTDP-L-megosamine biosynthesis
        • M00801 dTDP-L-olivose biosynthesis
        • M00802 dTDP-D-forosamine biosynthesis
        • M00803 dTDP-D-angolosamine biosynthesis
    • Biosynthesis of other secondary metabolites 
      • beta-Lactam biosynthesis 
        • M00672 Penicillin biosynthesis, aminoadipate + cycteine + valine => penicillin
        • M00673 Cephamycin C biosynthesis, aminoadipate + cycteine + valine => cephamycin C
        • M00675 Carbapenem-3-carboxylate biosynthesis, pyrroline-5-carboxylate + malonyl-CoA => carbapenem-3-carboxylate
        • M00736 Nocardicin A biosynthesis, L-pHPG + arginine + serine => nocardicin A
        • M00674 Clavaminate biosynthesis, arginine + glyceraldehyde-3P => clavaminate
      • Biosynthesis of other secondary metabolites 
        • M00039 Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
        • M00137 Flavanone biosynthesis, phenylalanine => naringenin
        • M00138 Flavonoid biosynthesis, naringenin => pelargonidin
        • M00661 Paspaline biosynthesis, geranylgeranyl-PP + indoleglycerol phosphate => paspaline
        • M00370 Glucosinolate biosynthesis, tryptophan => glucobrassicin
        • M00814 Acarbose biosynthesis, sedoheptulopyranose-7P => acarbose
        • M00815 Validamycin A biosynthesis, sedoheptulopyranose-7P => validamycin A
        • M00786 Fumitremorgin alkaloid biosynthesis, tryptophan + proline => fumitremorgin C/A
        • M00789 Rebeccamycin biosynthesis, tryptophan => rebeccamycin
        • M00790 Pyrrolnitrin biosynthesis, tryptophan => pyrrolnitrin
        • M00805 Staurosporine biosynthesis, tryptophan => staurosporine
        • M00808 Violacein biosynthesis, tryptophan => violacein
        • M00835 Pyocyanine biosynthesis, chorismate => pyocyanine
        • M00837 Prodigiosin biosynthesis, L-proline => prodigiosin
        • M00838 Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
        • M00877 Kanosamine biosynthesis glucose 6-phosphate => kanosamine
        • M00785 Cycloserine biosynthesis, arginine/serine => cycloserine
        • M00787 Bacilysin biosynthesis, prephenate => bacilysin
        • M00848 Aurachin biosynthesis, anthranilate => aurachin A
        • M00788 Terpentecin biosynthesis, GGAP => terpentecin
        • M00819 Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
        • M00876 Staphyloferrin A biosynthesis, L-ornithine => staphyloferrin A
        • M00875 Staphyloferrin B biosynthesis, L-serine => staphyloferrin B
    • Xenobiotics biodegradation 
      • Aromatics degradation 
        • M00538 Toluene degradation, toluene => benzoate
        • M00537 Xylene degradation, xylene => methylbenzoate
        • M00419 Cymene degradation, p-cymene => p-cumate
        • M00547 Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol
        • M00548 Benzene degradation, benzene => catechol
        • M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol
        • M00637 Anthranilate degradation, anthranilate => catechol
        • M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate
        • M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
        • M00539 Cumate degradation, p-cumate => 2-oxopent-4-enoate + 2-methylpropanoate
        • M00543 Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
        • M00544 Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate
        • M00418 Toluene degradation, anaerobic, toluene => benzoyl-CoA
        • M00541 Benzoyl-CoA degradation, benzoyl-CoA => 3-hydroxypimeloyl-CoA
        • M00540 Benzoate degradation, cyclohexanecarboxylic acid =>pimeloyl-CoA
        • M00534 Naphthalene degradation, naphthalene => salicylate
        • M00638 Salicylate degradation, salicylate => gentisate
        • M00624 Terephthalate degradation, terephthalate => 3,4-dihydroxybenzoate
        • M00623 Phthalate degradation, phthalate => protocatechuate
        • M00636 Phthalate degradation, phthalate => protocatechuate
      • Signature modules 

  • Reaction module
    • 2-Oxocarboxylic acid chain extension 
    • 2-Oxocarboxylic acid chain modification 
    • Fatty acid synthesis and degradation 
    • Acyl-CoA metabolism 
    • Methyl to carboxyl conversion on aromatic ring 
    • Dihydroxylation of aromatic ring 
    • Cleavage of aromatic ring 
    • Dihydroxylation and cleavage of aromatic ring 
    • Amino acid metabolism 
    • Nucleotide metabolism 
    • Sugar metabolism 
    • Aromatics metabolism 
    • Polyketide biosynthesis