=====================================
README for the "medicus" subdirectory
=====================================

The health information category of KEGG (also called KEGG MEDICUS) contains
our knowledge of diseases, drugs, and associated molecular networks.
It consists of NETWORK, VARIANT, DISEASE, DRUG, and DGROUP databases.
The identifier of each database takes the form shown below, where GeneID+
represents human gene identifier (equivalent to NCBI Gene ID) followed by
a variant number.

  Database      Identifier  Content
  ------------  ----------  -----------------------------------------
  KEGG NETWORK   N number   Disease-related network elements
                 nt number  Network variation maps
  KEGG VARIANT   GeneID+    Human gene variants
  KEGG DISEASE   H number   Human diseases
  KEGG DRUG      D number   Approved drugs
  KEGG DGROUP    DG number  Drug groups

This directory contains tarballs for these databases:

  network.tar.gz
  variant.tar.gz
  disease.tar.gz
  drug.tar.gz
  dgroup.tar.gz

where each of them is organized in the following way.

network.tar.gz
---------------
  network          DBGET flat file containing all NETWORK entries
  links/           ID mapping files of NETWORK to/from other KEGG DBs
                   and PubMed

variant.tar.gz
---------------
  variant          DBGET flat file containing all VARIANT entries
  links/           ID mapping files of VARIANT to/from other KEGG DBs
                   and PubMed

disease.tar.gz
---------------
  disease          DBGET flat file containing all DISEASE entries
  disease_ja       DBGET flat file in Japanese
  links/           ID mapping files of DISEASE to/from other KEGG DBs
                   and PubMed

drug.tar.gz
-------------
  drug             DBGET flat file containing all DRUG entries
  drug_ja          DBGET flat file in Japanese
  gif/             Chemical structure image files
  mol/             MDL/MOL files for chemical structures
  kcf/             KEGG/KCF files for chemical structures
  drug.inchi       Inchi file for chemical structures
  drug_update.lst  Update status of DRUG entries
  drug_product_jp.list  YJ codes and D numbers for drug products in Japan
  drug_product_us.list  NDCs and D numbers for drug products in the USA
  links/           ID mapping files of DRUG to/from other KEGG DBs,
                   PubChem, ChEBI, ATC, JTC, NDC and YJ.

dgroup.tar.gz
---------------
  dgroup           DBGET flat file containing all DGROUP entries
  dgroup_ja        DBGET flat file in Japanese
  gif/             Chemical structure image files
  mol/             MDL/MOL files for chemical structures
  kcf/             KEGG/KCF files for chemical structures
  links/           ID mapping files of DGROUP to/from other KEGG DBs


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Updated: August 17, 2021

(c) Kanehisa Laboratories