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hsa00010 Glycolysis / Gluconeogenesis Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: ... C00033 (Acetate) C00031 (D-Glucose) C00103 (D-Glucose 1-phosphate) C00631 (2-Phospho-D-glycerate) C00267 (alpha-D-Glucose) C00221 (beta-D-Glucose) C00111 (Glycerone phosphate) C01172 (beta-D-Glucose 6-phosphate) C00668 ... 4.1.2.13 1.2.1.3 6.2.1.13 1.2.1.5 Acetate Pentose phosphate pathway Starch and sucrose metabolism 4.1.1.1 1.1.1.2 1.1.1.1 4.1.1.1 1.2.4.1 1.2.4.1 2.3.1.12 1.1.1.27 Pyruvate metabolism 2.7.1.40 Citrate ...
hsa00020 Citrate cycle (TCA cycle) The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of ... C00022 (Pyruvate) C00122 (Fumarate) C00036 (Oxaloacetate) C05379 (Oxalosuccinate) C00024 (Acetyl-CoA) C00149 ((S)-Malate) C00311 (Isocitrate) C00417 (cis-Aconitate) C00042 (Succinate) C00158 (Citrate) C15972 ... 1.8.1.4 1.2.4.2 1.2.4.2 2.3.1.61 6.2.1.5 6.2.1.4 1.1.1.42 1.1.1.41 1.1.1.42 2.3.3.8 4.2.1.2 4.2.1.3 4.2.1.3 2.3.3.1 1.1.1.37 6.4.1.1 Glyoxylate and dicarboxylate metabolism Glycolysis / Gluconeogenesis Fatty ...
hsa00030 Pentose phosphate pathway The pentose phosphate pathway is a process of glucose turnover that produces NADPH as reducing equivalents and pentoses as essential parts of nucleotides. There are two different phases in the pathway ... C01151 (D-Ribose 1,5-bisphosphate) C00668 (alpha-D-Glucose 6-phosphate) C00118 (D-Glyceraldehyde 3-phosphate) C00022 (Pyruvate) C00257 (D-Gluconic acid) C00198 (D-Glucono-1,5-lactone) C00031 (D-Glucose) C00221 ... 2.7.4.23 5.3.1.9 4.1.2.14 Glycolysis 2.7.1.15 5.4.2.7 4.1.2.4 2.7.6.1 5.4.2.7 2.7.1.15 2.2.1.1 5.3.1.6 5.1.3.1 2.2.1.1 4.1.2.13 2.7.1.11 3.1.3.11 5.3.1.9 1.1.1.43 2.7.1.13 1.1.1.44 3.1.1.31 1.1.1.49 4 ...
hsa00040 Pentose and glucuronate interconversions C14899 (3-Dehydro-L-gulonate 6-phosphate) C03033 (beta-D-Glucuronoside) C00817 (D-Altronate) C00103 (D-Glucose 1-phosphate) C00905 (D-Fructuronate) C00514 (D-Mannonate) C00558 (D-Tagaturonate) C00800 (L-Gulonate) C05385 ... 3.2.1.15 3-Dehydro-L-gulonate-6P 4.1.1.85 2.7.1.53 β-D-Glucuronoside 3.2.1.31 5.3.1.4 1.1.1.13 2.7.1.16 1.1.1.56 2.7.1.47 2.7.1.16 5.1.3.1 5.1.3.4 1.1.1.137 2.7.7.40 5.1.3.22 1.1.1.11 2.7.1.17 5.3.1.15 4 ...
hsa00051 Fructose and mannose metabolism C00247 (L-Sorbose) C00267 (alpha-D-Glucose) C01094 (D-Fructose 1-phosphate) C00159 (D-Mannose) C00275 (D-Mannose 6-phosphate) C00392 (Mannitol) C00644 (D-Mannitol 1-phosphate) C03267 (beta-D-Fructose 2-phosphate) C00665 ... 2.7.1.202 Galactose metabolism 1.1.99.21 1.1.1.21 1.1.1.14 5.3.1.5 2.7.1.3 5.3.1.7 1.1.1.11 1.1.1.67 1.1.1.138 3.1.3.- 3.1.3.22 2.7.1.197 3.1.3.54 3.2.1.78 2.7.1.1 2.7.1.7 2.7.1.191 2.7.1.1 2.7.1.4 3.1 ...
hsa00052 Galactose metabolism C06311 (Galactitol 1-phosphate) C01216 (2-Dehydro-3-deoxy-D-galactonate) C00137 (myo-Inositol) C00095 (D-Fructose) C03383 (D-Galactono-1,4-lactone) C00124 (D-Galactose) C00052 (UDP-alpha-D-galactose) C00103 ... 1.1.1.251 2.7.1.200 3.2.1.22 2.7.1.144 2.7.1.11 4.1.2.40 4.1.2.21 3.2.1.85 3.2.1.22 3.2.1.26 2.4.1.67 3.2.1.20 3.2.1.22 3.2.1.26 2.7.1.207 1.1.1.21 3.2.1.22 3.2.1.22 3.2.1.22 3.2.1.22 2.7.1.2 2.7.1.1 3 ...
hsa00053 Ascorbate and aldarate metabolism C00137 (myo-Inositol) C05385 (D-Glucuronate 1-phosphate) C00167 (UDP-glucuronate) C00029 (UDP-glucose) C01825 (L-Galactose) C15930 (L-Galactonate) C15926 (beta-L-Galactose 1-phosphate) C15923 (L-Gulose) C15925 ... 3.1.1.- 1.1.1.365 1.1.1.122 3.1.3.93 2.7.7.69 5.1.3.18 5.1.3.18 5.1.3.18 1.13.99.1 2.7.1.43 2.7.7.44 1.1.1.22 myo-Inositol D-Glucuronate-1P UDP-D-glucuronate UDP-D-glucose L-Galactose L-Galactonate L-Galactose-1P L-Gulose GDP-L-gulose GDP-L-galactose GDP-D-mannose 1 ...
hsa00061 Fatty acid biosynthesis C04088 (Octadecanoyl-[acyl-carrier protein]) C16221 ((2E)-Octadecenoyl-[acp]) C16220 ((R)-3-Hydroxyoctadecanoyl-[acp]) C16219 (3-Oxostearoyl-[acp]) C00712 ((9Z)-Octadecenoic acid) C01530 (Octadecanoic ... FabK FabK FabK FabK FabK FabK FabL Octadecanoyl-[acp] trans-Octadec-2-enoyl-[acp] (R)-3-Hydroxy-octadecanoyl-[acp] 3-Oxooctadecanoyl-[acp] Octadecenoic acid Octadecanoic acid Hexadecenoic acid Octa-decenoyl-[acp] Hexa-decenoyl-[acp] Tetradecanoic ...
hsa00062 Fatty acid elongation C00024 (Acetyl-CoA) C00136 (Butanoyl-CoA) C05270 (Hexanoyl-CoA) C05271 (trans-Hex-2-enoyl-CoA) C05268 ((S)-Hydroxyhexanoyl-CoA) C05269 (3-Oxohexanoyl-CoA) C01944 (Octanoyl-CoA) C05276 (trans-Oct-2-enoyl-CoA) C05266 ... 4.2.1.74 4.2.1.74 Fatty acid degradation FATTY ACID ELONGATION 3.1.2.22 1.3.1.38 4.2.1.17 1.1.1.211 2.3.1.16 1.3.1.38 4.2.1.17 1.1.1.211 2.3.1.16 1.3.1.38 4.2.1.17 1.1.1.211 2.3.1.16 1.3.1.38 4.2.1.17 1 ...
hsa00071 Fatty acid degradation C02990 (L-Palmitoylcarnitine) C00638 (Long-chain fatty acid) C05280 (cis,cis-3,6-Dodecadienoyl-CoA) C03561 ((R)-3-Hydroxybutanoyl-CoA) C01144 ((S)-3-Hydroxybutanoyl-CoA) C00877 (Crotonoyl-CoA) C00332 (Acetoacetyl-CoA) C00136 ... 1.3.99.- 1.3.99.- 1.3.99.- 1.3.99.- 1.3.99.- 1.3.99.- 1.3.99.- 1.3.8.1 1.1.1.35 4.2.1.17 Synthesis and degradation of ketone bodies 1.3.8.7 6.2.1.20 5.3.3.8 5.1.2.3 2.3.1.9 2.3.1.16 1.1.1.35 4.2.1.17 1 ...
hsa00072 Synthesis and degradation of ketone bodies C00332 (Acetoacetyl-CoA) C00356 ((S)-3-Hydroxy-3-methylglutaryl-CoA) C00207 (Acetone) C00164 (Acetoacetate) C01089 ((R)-3-Hydroxybutanoate) C00024 (Acetyl-CoA) 3157 (HMGCS1), 3158 (HMGCS2), H01123 (HMG-CoA ... SYNTHESIS AND DEGRADATION OF KETONE BODIES Fatty acid degradation 2.3.3.10 4.1.3.4 4.1.1.4 2.3.1.9 1.1.1.30 Pyruvate metabolism Glycolysis 2.8.3.5 Butanoate metabolism Acetoacetyl-CoA (S)-3-Hydroxy-3-methylglutaryl-CoA Acetone Acetoacetate (R)-3-Hydroxybutanoate Acetyl-CoA 00072 ...
hsa00100 Steroid biosynthesis C01673 (Calcitriol) C01561 (Calcidiol) C01902 (Cycloartenol) C05442 (Stigmasterol) C15776 (4alpha-Methylfecosterol) C11508 (4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol) C01802 (Desmosterol) C01789 ... STE1 5.3.3.5 1.3.1.21 1.14.19.20 5.3.3.5 ERG4 ERG5 ERG3 ERG2 Brassinosteroid biosynthesis Calcitriol Calcidiol DWF1 DWF5 STE1 1.3.1.72 1.3.1.72 1.3.1.72 1.3.1.72 1.3.1.72 5.4.99.8 5.5.1.9 Cycloartenol DWF1 CYP51G1 SMT2 SMT1 DWF5 Stigmasterol 4α-Methylfecosterol δ8 ...
hsa00120 Primary bile acid biosynthesis Bile acids are steroid carboxylic acids derived from cholesterol in vertebrates. The primary bile acids, cholic acid and chenodeoxycholic acid, are synthesized in the liver and conjugated with taurine ... C00187 (Cholesterol) C03594 (7alpha-Hydroxycholesterol) C15610 (Cholest-5-ene-3beta,26-diol) C15519 (25-Hydroxycholesterol) C13550 (Cerebrosterol) C05455 (7alpha-Hydroxycholest-4-en-3-one) C17336 (7alpha ... 1.14.14.25 1.14.14.29 1.14.14.23 1.14.14.29 1.3.1.3 1.1.1.50 1.14.15.15 5.1.99.4 1.17.99.3 1.1.1.50 1.14.99.38 1.14.14.23 4.2.1.107 2.3.1.176 2.3.1.176 6.2.1.7 2.3.1.65 3.5.1.24 1.14.15.15 1.14.15.15 1 ...
hsa00130 Ubiquinone and other terpenoid-quinone biosynthesis Ubiquinone (UQ), also called coenzyme Q, and plastoquinone (PQ) are electron carriers in oxidative phosphorylation and photosynthesis, respectively. The quinoid nucleus of ubiquinone is derived from the ... C16519 (2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate) C03657 (1,4-Dihydroxy-2-naphthoate) C06986 (Spirodilactone) C00885 (Isochorismate) C00156 (4-Hydroxybenzoate) C00399 (Ubiquinone) ... UBIQUINONE AND OTHER TERPENOID-QUINONE BIOSYNTHESIS Phenylpropanoid biosynthesis 2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate 4.2.99.20 1,4-Dihydroxy-2-naphthoate Spirodilactone Phenylalanine ...
hsa00140 Steroid hormone biosynthesis Steroid hormones derived from cholesterol are a class of biologically active compounds in vertebrates. The cholesterol side-chain cleavage enzyme CYP11A1 catalyzes conversion of cholesterol, a C27 compound ... C05138 (17alpha-Hydroxypregnenolone) C05485 (21-Hydroxypregnenolone) C05489 (11beta,17alpha,21-Trihydroxypregnenolone) C00735 (Cortisol) C00762 (Cortisone) C05481 (Cortolone) C05471 (11beta,17alpha,21-Trihydroxy-5beta-pregnane-3 ... 1.1.1.62 STEROID HORMONE BIOSYNTHESIS 17α-Hydroxy-pregnenolone 21-Hydroxy-pregnenolone 11β,17α,21-Trihydroxy-pregnenolone Cortisol Cortisone Cortolone 11β,17α,21-Trihydroxy-5β-pregnane-3,20-dione Urocortisol Cortol 11β-Hydroxytestosterone 21-Deoxycortisol 11β-Hydroxy-progesterone 5α-Pregnan-20α-ol-3-one 3α-Hydroxy-5α-pregnan-20-one 3α-Hydroxy-5β-pregnane-20-one 5α-Pregnane-3α ...
hsa00190 Oxidative phosphorylation C00061 (FMN) C00390 (Ubiquinol) C00399 (Ubiquinone) C00524 (Cytochrome c) C00080 (H+) C00080 (H+) C00004 (NADH) C00003 (NAD+) C00080 (H+) C00122 (Fumarate) C00080 (H+) C00080 (H+) C00080 (H+) C00007 (Oxygen) C00001 ... F-type ATPase (Eukaryotes) V/A-type ATPase (Bacteria, Archaea) V-type ATPase (Eukaryotes) F-type ATPase (Bacteria) Cytochrome c oxidase Cytochrome c reductase Cytochrome c oxidase , cbb3-type Cytochrome ...
hsa00220 Arginine biosynthesis C03406 (N-(L-Arginino)succinate) C00327 (L-Citrulline) C00062 (L-Arginine) C00077 (L-Ornithine) C00169 (Carbamoyl phosphate) C00049 (L-Aspartate) C00122 (Fumarate) C00014 (Ammonia) C00624 (N-Acetyl-L-glutamate) C04133 ... L-Arginosuccinate Citruline Arginine Ornithine Carbamoyl-P Aspartate Fumarate NH3 N-Acetyl-glutamate N-Acetyl-glutamyl-P N-Acetylglutamate semialdehyde Glutamine Urea Urea-1-carboxylate 3.5.1.2 6.3.1.2 2 ...
hsa00230 Purine metabolism C12248 (5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate) C11821 (5-Hydroxyisourate) C02091 ((S)-Ureidoglycine) C00802 (Oxalureate) C00169 (Carbamoyl phosphate) C00014 (Ammonia) C00288 (HCO3-) C00117 ... 1.17.4.1 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate 5-Hydroxyisourate 1.17.3.2 3.5.3.26 3.5.3.9 Ureidoglycine Oxalureate Carbamoyl phosphate Hydrogen carbonate 1.1.1.154 2.1.3.5 PURINE ...
hsa00232 Caffeine metabolism C00385 (Xanthine) C13747 (1,7-Dimethylxanthine) C16362 (3,6,8-Trimethylallantoin) C16363 (N-Methylurea) C00048 (Glyoxylate) C16364 (N,N'-Dimethylurea) C16359 (1-Methyluric acid) C16357 (3-Methylxanthine) C16355 ... Xanthine Paraxanthine 3,6,8-Trimethyl-allantoin N-Methylurea Glyoxylate N,N'-Dimethylurea 1-Methyluric acid 3-Methylxanthine 7-Methyluric acid CYP1A2 1.13.12.- 1.17.3.2 1.14.13.178 1.14.13.179 1.7.3.3 1 ...
hsa00240 Pyrimidine metabolism C00063 (CTP) C15607 (3-Oxo-3-ureidopropanoate) C00064 (L-Glutamine) C00438 (N-Carbamoyl-L-aspartate) C00169 (Carbamoyl phosphate) C00337 ((S)-Dihydroorotate) C00119 (5-Phospho-alpha-D-ribose 1-diphosphate) C01103 ... (extracellular) CTP 1.17.4.1 3-Oxo-3-ureido-propanoate 3.5.1.95 2.7.4.22 3.5.4.30 2.1.1.148 L-Glutamine 6.3.5.5 PYRIMIDINE METABOLISM Pentose phosphate pathway Alanine, aspartate and glutamate metabolism β-Alanine ...
hsa00250 Alanine, aspartate and glutamate metabolism C00122 (Fumarate) C00042 (Succinate) C00036 (Oxaloacetate) C00026 (2-Oxoglutarate) C00041 (L-Alanine) C00049 (L-Aspartate) C00152 (L-Asparagine) C00402 (D-Aspartate) C02362 (2-Oxosuccinamate) C01042 (N-Acetyl-L-aspartate) C03794 ... Fumarate Succinate Oxaloacetate 2-Oxo-glutarate Citrate cycle L-Alanine L-Aspartate L-Asparagine D-Aspartate 2-Oxosuccinamate N-Acetyl-L-aspartate 3.5.1.3 6.3.1.1 6.3.5.4 2.6.1.14 4.1.1.12 3.5.1.1 3.5 ...
hsa00260 Glycine, serine and threonine metabolism Serine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis [MD:M00020], and glycine is derived from serine. Threonine is an essential amino acid, which animals cannot synthesize. In bacteria ... C16432 (5-Hydroxyectoine) C06231 (Ectoine) C06442 (N(gamma)-Acetyldiaminobutyrate) C03283 (L-2,4-Diaminobutanoate) C02855 (N-Phospho-D-lombricine) C02972 (Dihydrolipoylprotein) C02051 (Lipoylprotein) C00258 ... 1.1.3.17 5.1.1.18 5-Hydroxyectoine 1.14.11.55 1.14.15.7 L-Ectoine Nγ-Acetyl-L-2,4-diaminobutyrate L-2,4-Diamino-butanoate 4.2.1.108 2.3.1.178 2.6.1.76 1.1.3.17 1.1.99.1 3.1.3.38 1.2.1.8 2.7.1.31 Alanine ...
hsa00270 Cysteine and methionine metabolism Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from ... C06547 (Ethylene) C01234 (1-Aminocyclopropane-1-carboxylate) C08276 (3-(Methylthio)propanoate) C15606 (1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one) C15651 (2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate) C15650 ... Glycolysis 2.5.1.- Ethylene 1-Aminocyclopropane-1-carboxylate 1.14.17.4 4.4.1.14 2.6.1.117 3-Methylthio-propionate 1,2-Dihydroxy-3-keto-5-methyl-thiopentene 2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate 2 ...
hsa00280 Valine, leucine and isoleucine degradation C15978 (2-Methyl-1-hydroxybutyl-ThPP) C15973 (Enzyme N6-(dihydrolipoyl)lysine) C15973 (Enzyme N6-(dihydrolipoyl)lysine) C15972 (Enzyme N6-(lipoyl)lysine) C15972 (Enzyme N6-(lipoyl)lysine) C15976 (2-Methyl-1-hydroxypropyl-ThPP) C00068 ... 2-Methyl-1-hydroxybutyl-ThPP 1.2.4.4 1.8.1.4 Dihydro-lipoamide-E Dihydro-lipoamide-E Lipoamide-E Lipoamide-E 2-Methyl-1-hydroxypropyl-ThPP ThPP ThPP 1.8.1.4 1.2.4.4 Dihydro-lipoamide-E Lipoamide-E ThPP 1 ...
hsa00310 Lysine degradation C05825 (2-Amino-5-oxohexanoate) C05161 ((2R,5S)-2,5-Diaminohexanoate) C00877 (Crotonoyl-CoA) C01144 ((S)-3-Hydroxybutanoyl-CoA) C00332 (Acetoacetyl-CoA) C00024 (Acetyl-CoA) C00322 (2-Oxoadipate) C00527 ... 2.6.1.21 2-Amino-5-oxohexanoate 2,5-Diaminohexanoate 1.4.1.12 5.4.3.3 1.5.1.1 1.5.1.8 1.5.1.10 Penicillins and cephalosporins biosynthesis 4.2.1.17 1.1.1.35 1.5.99.3 1.5.1.21 2.6.1.65 3.5.1.17 2.3.1.32 1 ...
hsa00330 Arginine and proline metabolism C00062 (L-Arginine) C00077 (L-Ornithine) C00134 (Putrescine) C00555 (4-Aminobutyraldehyde) C00334 (4-Aminobutanoate) C15699 (gamma-L-Glutamylputrescine) C15700 (gamma-Glutamyl-gamma-aminobutyraldehyde) C15767 ... ARGININE AND PROLINE METABOLISM Polyamine Pathway ADC pathway ADH pathway 3.5.3.1 2.6.1.84 4.1.1.75 1.2.1.54 3.5.3.7 2.1.4.1 3.5.1.4 1.13.12.1 PuuA PuuB PuuC PuuD 1.4.3.10 2.6.1.29 2.6.1.113 1.4.3.22 2 ...
hsa00340 Histidine metabolism C00119 (5-Phospho-alpha-D-ribose 1-diphosphate) C02739 (1-(5-Phospho-D-ribosyl)-ATP) C02741 (Phosphoribosyl-AMP) C04896 (5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide) C04916 ... 1.14.13.- 3.5.3.13 3.5.1.68 3.5.3.8 2.1.2.5 3.5.2.7 4.2.1.49 4.3.1.3 3.4.13.5 2.1.1.22 3.4.13.18 6.3.2.11 3.5.3.5 1.14.13.5 6.3.4.8 1.2.1.3 1.4.3.4 1.2.1.5 1.4.3.22 2.1.1.8 Pentose phosphate pathway 2 ...
hsa00350 Tyrosine metabolism C06044 (4-Hydroxyphenylethanol) C06046 (Salidroside) C04186 (5-Carboxymethyl-2-hydroxymuconate) C04642 (2-Hydroxy-5-carboxymethylmuconate semialdehyde) C04052 (5-Carboxy-2-oxohept-3-enedioate) C05600 (2-Hydroxyhepta-2 ... Isoquinoline alkaloid biosynthesis 4-Hydroxy-phenylethanol Salidroside Dioxin degradation TYROSINE METABOLISM Phenylalanine, tyrosine and ryptophan biosynthesis 1.11.1.8 1.11.1.8 1.11.1.8 3.7.1.5 5.2 ...
hsa00360 Phenylalanine metabolism C12621 (trans-3-Hydroxycinnamate) C00084 (Acetaldehyde) C00022 (Pyruvate) C03589 (4-Hydroxy-2-oxopentanoate) C00596 (2-Hydroxy-2,4-pentadienoate) C00122 (Fumarate) C12624 (2-Hydroxy-6-ketononatrienedioate) C12623 ... 4.1.3.39 4.3.1.25 Tropane, piperidine and pyridine alkaloid biosynthesis 1.2.1.5 6.2.1.30 2.3.1.14 4.2.1.80 3.7.1.14 3.7.1.14 1.13.11.16 1.13.11.16 4.3.1.24 1.14.13.127 4.1.1.28 4.1.1.53 1.4.9.2 1.4.3 ...
hsa00380 Tryptophan metabolism C05663 (6-Hydroxykynurenate) C05639 (4,6-Dihydroxyquinoline) C05652 (4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate) C05638 (5-Hydroxykynurenamine) C05651 (5-Hydroxykynurenine) C05648 (5-Hydroxy-N-formylkynurenine) C02172 ... 1.11.1.6 1.1.1.35 1.13.11.52 4.1.1.74 Nicotinamide metabolism 2.6.1.27 1.4.3.2 1.13.11.52 1.14.14.1 2.1.1.4 2.1.1.- 2.3.1.87 1.13.11.52 2.1.1.4 1.4.3.4 4.1.1.28 2.6.1.- 4.1.1.28 1.13.11.52 2.6.1.27 1.13 ...
hsa00400 Phenylalanine, tyrosine and tryptophan biosynthesis C00279 (D-Erythrose 4-phosphate) C00074 (Phosphoenolpyruvate) C04691 (2-Dehydro-3-deoxy-D-arabino-heptonate 7-phosphate) C00944 (3-Dehydroquinate) C00296 (Quinate) C02637 (3-Dehydroshikimate) C00493 (Shikimate) C03175 ... Shikimate pathway 2.5.1.54 Phenylpropanoid biosynthesis Phenylpropanoid biosynthesis Biosynthesis of siderophore group nonribosomal peptides Acridone alkaloid biosynthesis Indole alkaloid biosynthesis Benzoxazinone ...
hsa00410 beta-Alanine metabolism C00429 (5,6-Dihydrouracil) C02642 (3-Ureidopropionate) C00099 (beta-Alanine) C00083 (Malonyl-CoA) C00024 (Acetyl-CoA) C00383 (Malonate) C05669 (beta-Nitropropanoate) C05670 (3-Aminopropiononitrile) C01073 ... β-ALANINE METABOLISM Propanoate metabolism Fatty acid biosynthesis Pantothenate and CoA biosynthesis Pyrimidine metabolism 4.3.1.6 1.3.8.1 4.2.1.17 3.1.2.4 1.1.1.59 1.2.1.15 2.8.3.3 4.1.1.9 1.2.1.18 4 ...
hsa00430 Taurine and hypotaurine metabolism C00094 (Sulfite) C06735 (Aminoacetaldehyde) C00041 (L-Alanine) C00022 (Pyruvate) C14179 (Sulfoacetate) C00227 (Acetyl phosphate) C00024 (Acetyl-CoA) C00606 (3-Sulfino-L-alanine) C00519 (Hypotaurine) C01678 ... 1.14.11.17 Sulfur metabolism 1.1.2.- 1.2.1.73 1.4.1.1 Sulfite Aminoacetaldehyde L-Alanine Pyruvate Sulfoacetate 2.3.1.8 Acetyl phosphate 2.3.3.15 Pyruvate metabolism Acetyl-CoA 2.6.1.77 TAURINE AND HYPOTAURINE ...
hsa00440 Phosphonate and phosphinate metabolism Natural products containing carbon-phosphorous bonds, so-called C-P compounds, are derivatives of phosphonate and phosphinate with substitution of alkyl group for hydrogen of phosphorus-hydrogen bonds ... C00074 (Phosphoenolpyruvate) C02798 (3-Phosphonopyruvate) C05672 (2-Amino-3-phosphonopropanoate) C17942 (FR 900098) C03167 (Phosphonoacetaldehyde) C03557 (2-Aminoethylphosphonate) C05682 (Phosphonoacetate) C00033 ... PHOSPHONATE AND PHOSPHINATE METABOLISM Glycolysis Phosphoenol-pyruvate 3-Phosphono-pyruvate Phosphono-alanine FR 900098 Phosphono-acetaldehyde 2-Aminoethyl-phosphonate Phosphono-acetate Acetate Rhizocticin Hydroxymethyl-phosphonate Formyl-phosphonate 2-Methylamino-ethylphosphonate Ciliatocholate (2-Amino-1-hydroxyethyl)-phosphonate CMP-ciliatine Lipophosphonoglycan Ceramide ...
hsa00450 Selenocompound metabolism C01528 (Hydrogen selenide) C05697 (Selenate) C05684 (Selenite) C05172 (Selenophosphoric acid) C06481 (L-Seryl-tRNA(Sec)) C06482 (L-Selenocysteinyl-tRNA(Sec)) C05689 (Se-Methyl-L-selenocysteine) C05695 ... SELENOCOMPOUND METABOLISM 1.8.1.9 2.7.9.3 2.1.1.12 4.4.1.11 6.1.1.10 Hydrogen selenide Selenate Selenite Seleno-phosphate L-Seryl-tRNA(Sec) L-Seleno-cysteinyl-tRNA(Sec) Se-Methyl-seleno-cysteine γ-Glutamyl-Se-methylselenocysteine Selenocysteine Seleno-cystathionine Seleno-homocysteine Seleno-methionine Se-Methyl-seleno-methionine Seleno-methionyl-tRNA(Met) Protein 1 ...
hsa00471 D-Glutamine and D-glutamate metabolism C00064 (L-Glutamine) C00819 (D-Glutamine) C03933 (5-D-Glutamyl-D-glutamyl-peptide) C05723 (Poly-gamma-D-glutamate) C00025 (L-Glutamate) C00217 (D-Glutamate) C02671 (D-Glutamyl-peptide) C00692 (UDP-N-acetylmuramoyl-L-alanyl-D-glutamate) C01212 ... D-GLUTAMINE AND D-GLUTAMATE METABOLISM Peptidoglycan biosynthesis Amino sugar and nucleotide sugar metabolism Citrate cycle Glutamate metabolism Cyanoamino acid metabolism 2.3.2.1 6.3.2.8 6.3.2.9 4 ...
hsa00480 Glutathione metabolism C00024 (Acetyl-CoA) C00151 (L-Amino acid) C01879 (5-Oxoproline) C00097 (L-Cysteine) C00025 (L-Glutamate) C00037 (Glycine) C01419 (Cys-Gly) C03740 ((5-L-Glutamyl)-L-amino acid) C00051 (Glutathione) C00669 ... Acetyl-CoA GLUTATHIONE METABOLISM Glutamate metabolism Taurine and hypotaurine metabolism Cyanoamino acid metabolism Cysteine and methionine metabolism 1.8.1.13 3.4.11.2 2.3.2.2 1.11.1.9 1.8.4.4 1.8 ...
hsa00500 Starch and sucrose metabolism C00092 (D-Glucose 6-phosphate) C00092 (D-Glucose 6-phosphate) C00095 (D-Fructose) C05731 (3-Ketosucrose) C02591 (Sucrose 6'-phosphate) C00089 (Sucrose) C00029 (UDP-glucose) C00031 (D-Glucose) C00085 (D-Fructose ... 3.6.1.- D-Glucose-6P 3.2.1.21 3.2.1.21 2.7.1.1 3.2.1.122 STARCH AND SUCROSE METABOLISM 3.2.1.26 2.7.1.4 1.1.99.13 3.2.1.20 3.2.1.26 3.2.1.48 3.2.1.21 3.2.1.39 3.2.1.4 3.1.3.24 2.4.1.29 2.7.1.211 2.4 ...
hsa00510 N-Glycan biosynthesis N-glycans or asparagine-linked glycans are major constituents of glycoproteins in eukaryotes. N-glycans are covalently attached to asparagine with the consensus sequence of Asn-X-Ser/Thr by an N-glycosidic ... G10596 G00022 G00021 G00020 G00019 G00018 (DS 3) G00017 G00016 G00015 G00014 G00013 G00012 G00011 G00171 G00009 G00008 G00007 G00006 G00005 G00004 G00003 G00002 (N,N'-Chitobiosyldiphosphodolichol) G00001 ... ALG14 DPM3 DPM2 Various types of N-glycan biosynthesis ALG6 ALG12 ALG9 ALG3 N-glycan degradation MGAT5 Keratan sulfate biosynthesis Glycosylphosphatidyl-inositol (GPI) -anchor biosynthesis 3.6.1.43 Fructose ...
hsa00511 Other glycan degradation 10825 (NEU3), 129807 (NEU4), 4758 (NEU1), 4759 (NEU2), H00142 (Sialidosis), H00422 (Glycoproteinoses) 2720 (GLB1), H00123 (Mucopolysaccharidosis type IV), H00281 (GM1 gangliosidosis), H00421 (Mucopolysaccharidosis) ... OTHER GLYCAN DEGRADATION GlcNAc GlcNAc Fuc Neu5Ac Gal Asn α2 β1 β1 Man α1 GlcNAc Neu5Ac Gal α2 β1 β1 Man α1 β1 GlcNAc Man β1 β1 GlcNAc β1 α1 Fuc α1 Neu5Ac α2 Neu5Ac α2 Gal β1 Neu5Ac α2 Neu5Ac α2 GalNAc Neu5Ac α2 Neu5Ac α2 Neu5Ac α2 β1 Gal β1 Glc β1 ceramide Ganglioside N-glycan N-Glycan ...
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