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Name |
Description |
Object |
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hsa00512
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Mucin type O-glycan biosynthesis
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O-glycans are a class of glycans that modify serine or threonine residues of proteins. Biosynthesis of O-glycans starts from the transfer of N-acetylgalactosamine (GalNAc) to serine or threonine. The first ...
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G00034
G00033
G00032
G00031
G00030
G00029
G00028
G00027
G00026 (Sialyl T antigen)
G00025
G00023 (Tn antigen)
G00035 (Sialyl-Tn antigen)
C02189 ([Protein]-L-serine)
G10611 (UDP-N-acetyl-D-galactosamine)
G00024 ...
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Keratan sulfate biosynthesis
Core 8
Core 7
(F1α)
Core 6
Core 5
Core 4
Core 3
(disialyl-T antigen)
(sialyl-T antigen)
Core 2
(Tn antigen)
(sialyl-Tn antigen)
2.4.1.148
2.4.1.148
2.4.1.102
B4GALT5
2.4.3 ...
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hsa00513
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Various types of N-glycan biosynthesis
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G11040
G10841
G01813
G12625
G12626
G00012
G00011
G13047
G13048
G13049
G13050
G00016 (Core fucose)
G00017
G10716
G11000
G11933
G00014
G00013
G00012
G00011
G00015
G00011
G00012
G00013
G00014
G10770
G13057
G13058
G13059
G00011
G00012
G00013
G00014
G10770
G05477
G10920
G00015
G12617
G13055
G13056
G00011
G00012
G00013
G00014
G10694
G00179
G10665
G10694
G10694
G10694
G10694
10905 ...
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MNN1
N-Glycan biosynthesis
MNN9
ANP1
MNN2
MNN1
MNN6
MNN11
VAN1
MAN1A
MNN9
OCH1
MNN5
HOC1
MNN10
VARIOUS TYPES OF N-GLYCAN BIOSYNTHESIS
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
Man
GlcNAc
Asn
GlcNAc
Man
Man
Man
GlcNAc
Asn
GlcNAc
Fuc
Xyl
GlcNAc
GlcNAc
Gal
Fuc
Gal
Fuc
High-mannose ...
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hsa00514
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Other types of O-glycan biosynthesis
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O-linked glycosylation is the attachment of monosaccharides to the hydroxyl groups of amino acids, mostly serine and threonine, and is found in eukaryotes, archaea and bacteria. O-glycans exhibit diverse ...
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23127 (COLGALT2), 79709 (COLGALT1), 8985 (PLOD3), H00877 (Brain small vessel disease), H01192 (Lysyl hydroxylase 3 deficiency)
145173 (B3GLCT), H01075 (Peters anomaly)
8985 (PLOD3), H01192 (Lysyl hydroxylase ...
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OTHER TYPES OF O-GLYCAN BIOSYNTHESIS
Glc
Hydroxylysine
Glc
Gal
O-linked Gal type
O-linked GlcNAc type
O-linked Man type (Yeast)
O-linked Fuc type
Neu5Ac
3/6
Gal
GlcNAc
Fuc
Ser/Thr
Xyl
Xyl
Glc
Ser/Thr
Ser/Thr
GlcNAc
O-linked ...
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hsa00515
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Mannose type O-glycan biosynthesis
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Biosynthesis of mammalian O-mannosyl glycans is initiated by the transfer of mannose from mannose-P-Dol to serine or threonine residue, followed by extensions with N-acetylglucosamine (GlcNAc) and galactose ...
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C02189 ([Protein]-L-serine)
G10617 (Dolichyl phosphate D-mannose)
G13082
G13027
G13026
G13085
G13088
G13100
G13028
G13086 (O-Mannose core M2)
G13083
G13089
G13090
G13087
G13092 (Phospho-core M3)
G13093
G13099
G13096
G13091 ...
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2.4.1.-
-Ser/Thr-peptide
Manβ-P-Dol
2.4.1.109
POMT1/POMT2
2.4.1.-
GalT
POMGNT1
2.4.3.6
2.4.1.135
SiaT
B3GAT1
2.8.2.-
2.4.1.152
FUT
Neu5Ac
Gal
GlcNAc
Man
Ser/Thr
GlcA
Gal
GlcNAc
Man
Ser/Thr
Gal
Fuc
GlcNAc
Man
Ser/Thr
2 ...
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hsa00520
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Amino sugar and nucleotide sugar metabolism
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C00357 (N-Acetyl-D-glucosamine 6-phosphate)
C00140 (N-Acetyl-D-glucosamine)
C04501 (N-Acetyl-alpha-D-glucosamine 1-phosphate)
C00043 (UDP-N-acetyl-alpha-D-glucosamine)
C00645 (N-Acetyl-D-mannosamine)
C04257 ...
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2.7.1.59
5.4.2.3
2.7.7.23
3.2.1.183
2.7.1.60
2.5.1.57
3.1.3.29
3.5.99.6
3.5.1.25
5.4.2.10
2.3.1.157
2.6.1.16
2.3.1.3
3.5.1.33
2.3.1.4
5.1.3.14
1.1.1.336
5.1.3.7
2.5.1.7
1.3.1.98
2.5.1.56
5.1.3.9
2.7.1 ...
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hsa00524
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Neomycin, kanamycin and gentamicin biosynthesis
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C00031 (D-Glucose)
C00092 (D-Glucose 6-phosphate)
C17209 (2-Deoxy-scyllo-inosose)
C17580 (2-Deoxy-scyllo-inosamine)
C17581 (3-Amino-2,3-dideoxy-scyllo-inosose)
C02627 (2-Deoxystreptamine)
C17582 (2'-N-Acetylparomamine)
C01743 ...
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NEOMYCIN, KANAMYCIN AND GENTAMICIN BIOSYNTHESIS
D-Glucose
D-Glucose-6P
2-Deoxy-scyllo-inosose
2-Deoxy-scyllo-inosamine
3-Amino-2,3-dideoxy-scyllo-inosose
2-Deoxystreptamine
2'-N-Acetylparomamin
Paromamine
Streptomycin ...
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hsa00531
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Glycosaminoglycan degradation
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G01391
G13074
G13073
G01977
G01945
G02632
G09660
G13040
G13039
G13038
G13037
G13036
G13035
G13034
G00872 (DWA-2)
G13043
G12336
G13042
G13041
C00925 (Heparan sulfate)
C00426 (Dermatan sulfate)
C00634 (Chondroitin ...
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3.10.1.1
HPSE2
HPSE
Heparan sulfate biosynthesis
Keratan sulfate biosynthesis
Chondroitin sulfate biosynthesis
3.1.6.14
GLYCOSAMINOGLYCAN DEGRADATION
Heparan sulfate
3.2.1.103
3.1.6.13
3.1.6.13
3.1.6 ...
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hsa00532
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Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
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Glycosaminoglycans (GAGs) are linear polysaccharide chains consisting of repeating disaccharide units and form proteglycans by covalently attaching to their core proteins. Chondroitin sulfate (CS) is a ...
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C00054 (Adenosine 3',5'-bisphosphate)
C00053 (3'-Phosphoadenylyl sulfate)
G00160
G00159
G00158
G00157
G00156
G00155
G00154
C02189 ([Protein]-L-serine)
C00401 (Chondroitin)
C01490 (Dermatan)
C00054 (Adenosine ...
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PAP
PAPS
2.4.1.135
2.4.2.26
2.4.1.133
GLYCOSAMINOGLYCAN BIOSYNTHESIS - CHONDROITIN SULFATE / DERMATAN SULFATE
Ser-peptide
Chondroitin
GalNAc
GlcA
GalNAc
GlcA
Gal
Gal
Xyl
Ser
GlcA
XYLT1,2
B4GALT7
B3GALT6
B3GAT3
...
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hsa00533
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Glycosaminoglycan biosynthesis - keratan sulfate
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Keratan sulfate (KS) is a glycosaminoglycan with the basic disaccharide unit of N-acetyllactosamine, Gal(b1-4)GlcNAc(b1-3), with sulfate esters at C-6 of GlcNAc and Gal residues. There are two types of ...
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10678 (B3GNT2)
2683 (B4GALT1), 8703 (B4GALT3), 8704 (B4GALT2), H00119 (Congenital disorders of glycosylation type II)
6487 (ST3GAL3), H00606 (Early infantile epileptic encephalopathy), H00768 (Autosomal ...
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Keratan sulfate II (KSII)
O-Glycan biosynthesis
GLYCOSAMINOGLYCAN BIOSYNTHESIS - KERATAN SULFATE
Keratan sulfate I (KSI)
Asn
GlcNAc
Man
Gal
GlcNAc
GlcNAc
GlcNAc
GlcNAc
GlcNAc
GlcNAc
Man
Man
Gal
Gal
Gal
Gal
0-40
10-12
NeuNAc
Fuc
CHST1
CHST6
B3GNT7
B4GALT4
B4GALT4
B3GNT2
B3GNT2
B4GALT1 ...
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hsa00534
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Glycosaminoglycan biosynthesis - heparan sulfate / heparin
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Heparan sulfate (HS) and heparin (Hep) are glycosaminoglycans with repeating disaccharide units that consist of alternating residues of alpha-D-glucosamine (GlcN) and uronic acid, the latter being either ...
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G00164
G00163
G00162
G00157
C00054 (Adenosine 3',5'-bisphosphate)
G00156
G00155
G00154
C02189 ([Protein]-L-serine)
C00053 (3'-Phosphoadenylyl sulfate)
C00033 (Acetate)
2135 (EXTL2), 2137 (EXTL3), H02491 ...
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2.4.1.223
EXTL2,3
EXTL1,3
EXT1,2
EXT1,2
GlcNAc
GlcNAc
GlcA
GlcA
Gal
Gal
Xyl
Ser
EXT1,2
EXTL1,3
XYLT1,2
B4GALT7
B3GALT6
B3GAT3
Disaccharide repeating region
Linkage region tetrasaccharide
GlcNAc
GlcA
EXT1 ...
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hsa00561
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Glycerolipid metabolism
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C00422 (Triacylglycerol)
C00641 (1,2-Diacyl-sn-glycerol)
C00111 (Glycerone phosphate)
C00093 (sn-Glycerol 3-phosphate)
C00197 (3-Phospho-D-glycerate)
C00258 (D-Glycerate)
C00577 (D-Glyceraldehyde)
C00184 ...
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2.3.1.158
SQD1
SQD2
2.4.1.241
2.4.3.5
Glycerophospholipid metabolism
3.1.1.3
2.3.1.20
2.4.1.46
2.4.1.337
3.1.3.4
2.3.1.22
3.1.1.3
2.3.1.51
Glycolysis
2.7.1.94
3.1.1.23
2.3.1.15
2.7.1.29
3.1.3.21
2.7.1 ...
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hsa00562
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Inositol phosphate metabolism
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C11557 (1-Phosphatidyl-1D-myo-inositol 5-phosphate)
C11555 (1D-myo-Inositol 1,4,5,6-tetrakisphosphate)
C01272 (1D-myo-Inositol 1,3,4,5-tetrakisphosphate)
C01204 (Phytic acid)
C01245 (D-myo-Inositol 1,4 ...
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1-Phosphatidyl-1D-myo-inositol-5P
2.7.1.149
1D-myo-Inositol- 1,4,5,6P
3.1.3.36
2.7.1.151
2.7.1.151
3.1.3.67
3.1.3.62
3.1.3.56
2.7.1.127
2.7.1.159
3.1.3.8
3.1.3.26
2.7.1.159
2.7.1.140
2.7.1.134
3.1.3.56
3 ...
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hsa00563
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Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
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Cell surface proteins can be attached to the cell membrane via the glycolipid structure called glycosylphosphatidylinositol (GPI) anchor. Hundreds of GPI-anchored proteins have been identified in many ...
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G13150
G12396 (6-(alpha-D-glucosaminyl)-1D-myo-inositol)
G00145
G00143
G00144
G00146
G13151
G13128
C00350 (Phosphatidylethanolamine)
G13152
G00149
G00148
C00350 (Phosphatidylethanolamine)
G10617 (Dolichyl ...
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PIG-Y
DPM2
PIG-Q
PIG-P
PIG-H
PIG-C
PIG-X
PIG-U
PIG-T
PIG-S
6-(α-D-Glucosaminyl)-1D-myo-inositol
PIG-M
Phosphatidyl-ethanolamine
PIG-F
PIG-L
PIG-K
PIG-B
GPAA1
PGAP1
PIG-N
PIG-A
3.1.4.50
PIG-O
PIG-W
PIG-V
Glycerophospholipid ...
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hsa00564
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Glycerophospholipid metabolism
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C06771 (Triethanolamine)
C06772 (Diethanolamine)
C00084 (Acetaldehyde)
C00641 (1,2-Diacyl-sn-glycerol)
C01996 (Acetylcholine)
C04230 (1-Acyl-sn-glycero-3-phosphocholine)
C00307 (CDP-choline)
C00588 (Choline ...
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Ether lipid metaboilsm
2.7.8.29
Ptdss1
Glycolysis
1.1.3.21
GPI-anchor biosynthesis
Triethanolamine
Diethanolamine
Acetaldehyde
4.3.3.-
4.3.3.-
Glycerolipid metabolism
2.3.1.42
2.7.8.24
2.3.1.52
2.3.1.62
LPCAT
2 ...
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hsa00565
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Ether lipid metabolism
|
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C15647 (2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate)
C15646 (1-(1-Alkenyl)-sn-glycero-3-phosphate)
C15645 (1-(1-Alkenyl)-sn-glycerol)
C02773 (1-Alkyl-sn-glycerol)
C01264 (2-Acetyl-1-alkyl-sn-glycero-3-phosphate)
C04756 ...
|
2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate (Plasmenic acid)
1-(1-Alkenyl)-sn-glycero-3-phosphate
1-(1-Alkenyl)-sn-glycerol
1-Alkyl-sn-glycerol
2-Acetyl-1-alkyl-sn-glycero-3-phosphate
2-Acyl-1-(1alkenyl)-sn-glycero-3-phosphoethanolamine ...
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hsa00590
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Arachidonic acid metabolism
|
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C03577 (20-Hydroxyleukotriene E4)
C14811 (Trioxilin B3)
C14809 (Trioxilin A3)
C14810 (Hepoxilin B3)
C14808 (Hepoxilin A3)
C14807 (12-OxoETE)
C14777 (12(S)-HETE)
C14822 (12(R)-HETE)
C14820 (11(R)-HPETE)
C14780 ...
|
Eicosanoids
3.3.2.10
3.3.2.10
3.3.2.10
3.3.2.10
1.14.13.34
20-OH-LTE
Trioxilin B
Trioxilin A
Hepoxilin B
Hepoxilin A
12-OxoETE
12(S)-HETE
12(R)-HETE
11(R)-HPETE
11(R)-HETE
9(S)-HPETE
9(S)-HETE
8(S)-HPETE
8(S)-HETE
8(R)-HPETE
8(R)-HETE
20-HETE
19(S)-HETE
2 ...
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hsa00591
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Linoleic acid metabolism
|
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C04717 ((9Z,11E)-(13S)-13-Hydroperoxyoctadeca-9,11-dienoic acid)
C14833 (9,12,13-TriHOME)
C14832 (12,13-Epoxy-9-hydroxy-10-octadecenoate)
C14766 (9-OxoODE)
C14765 (13-OxoODE)
C14767 (9(S)-HODE)
C14833 ...
|
3.3.2.-
3.3.2.-
CYP1A2
13(S)-HPODE
9,12,13-TriHOME
12,13-Epoxy-9-hydroxy-10-octadecenoate
9-OxoODE
13-OxoODE
9(S)-HODE
9,12,13-TriHOME
9,10,13-TriHOME
12,13-Epoxy-9-hydroxy-10-octadecenoate
9,10-Epoxy-13-hydroxy-11-octadecenoate
9 ...
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hsa00592
|
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alpha-Linolenic acid metabolism
|
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C11512 (Methyl jasmonate)
C16318 ((+)-7-Isomethyljasmonate)
C08491 ((-)-Jasmonic acid)
C16317 ((+)-7-Isojasmonic acid)
C16339 ((+)-7-Isojasmonic acid CoA)
C16338 (3-Oxo-OPC4-CoA)
C16336 (trans-2-Enoyl-OPC4-CoA)
C16335 ...
|
MFP2
MFP2
MFP2
HPL1
ACX
ACX
2.3.1.16
2.3.1.16
4.2.1.92
1.13.11.12
(-)-Methyl-jasmonate
(+)-7-Isomethyl-jasmonate
(-)-Jasmonate
(+)-7-Iso-jasmonate
JA-CoA
3-Oxo-OPC4-CoA
trans-2-Enoyl-OPC4-CoA
OPC4-CoA
3-Oxo-OPC6-CoA
trans-2-Enoyl-OPC6-CoA
OPC6-CoA
3-Oxo-OPC8-CoA
1 ...
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hsa00600
|
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Sphingolipid metabolism
|
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C00836 (Sphinganine)
C12144 (Phytosphingosine)
C12145 (Phytoceramide)
C12126 (Dihydroceramide)
C01290 (Lactosylceramide)
C06124 (Sphingosine 1-phosphate)
C01190 (Glucosylceramide)
C01120 (Sphinganine 1-phosphate)
C00346 ...
|
YDC1
YPC1
2.7.8.3
3.1.3.-
3.1.3.-
3.1.3.-
3.5.1.23
3.5.1.23
CERS
1.14.19.17
LAG1
1.14.18.5
1.14.18.5
3.1.4.12
CERS
2.7.8.-
2.7.8.48
3.1.4.41
2.7.1.138
3.1.3.4
3.1.3.4
3.1.3.4
Dihydro- sphingosine (Sphinganine)
Phyto-sphingosine
Phyto-ceramide
Dihydro-ceramide
Glycosphingolipid ...
|
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hsa00601
|
|
Glycosphingolipid biosynthesis - lacto and neolacto series
|
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G00078 (iso-nLc8Cer)
G00057 (Gal-TypeIIA glycolipid)
G00090 (V3Fuc,III3Fuc-nLc6Cer)
G00091
G00089 (V3Fuc-nLc6Cer)
G00088 (VI3NeuAc-nLc6Cer)
G00087 (VI6NeuAc-nLc6Cer)
G00086
G00067 (nLc6Cer)
G00085
G00084
G00069 ...
|
2.4.1.152
2.4.1.152
2.4.1.152
2.4.1.152
2.4.1.-
2.4.1.65
2.4.1.65
2.4.1.65
2.4.1.65
2.4.1.65
B4GALT4
B4GALT3
B4GALT4
B4GALT3
B4GALT2
2.4.1.-
2.4.1.-
2.4.1.-
2.4.1.-
2.4.1.-
2.4.1.-
2.4.1.65
2.4.1.65
2 ...
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|
hsa00603
|
|
Glycosphingolipid biosynthesis - globo and isoglobo series
|
|
G00181 (Disialosylglobopentaosylceramide)
G00096 (IV3GalNAcb-Gb4Cer)
G00100 (V3(NeuAc)2-Gb5Cer)
G00101
G00098 (Monosialylgalactosylgloboside)
G00097 (Galactosylgloboside)
G00104
G00103
G00102
G00106
G00105 ...
|
2.4.3.2
(SSEA-4)
(SSEA-3)
B3GALT5
2.4.1.-
3.2.1.49
2.4.1.228
Globoside (P antigen)
3.2.1.52
2.4.1.-
2.4.3.8
2.4.1.152
2.4.1.69
3.2.1.22
2.4.1.79
2.4.1.88
Sphingolipid metabolism
(Forssman)
Lactosylceramide
Neu5Ac
Neu5Ac
Neu5Ac
Fuc
Gal
GalNAc
GalNAc
GalNAc
Gal
Gal
Glc
ceramide
Neu5Ac
UGCG
B4GALT6
A4GALT
A4GALT
B3GALNT1
B3GALNT1
ST3GALT1 ...
|
|
hsa00604
|
|
Glycosphingolipid biosynthesis - ganglio series
|
|
G00129 (GQ1balpha)
G00128 (GT1aalpha)
G00127 (GD1a)
G00132 (GD1beta)
G00131 (GM1alpha)
G00130 (GM2alpha)
G00170 (9-O-Acetylated GT3)
G00122 (GP1c)
G00121 (GQ1c)
G00120 (GT1c)
G00119 (GT2)
G00118 (GT3)
G00169 ...
|
2.4.3.2
3.2.1.23
3.2.1.52
Siat8a
GQ1bα
GT1aα
GD1α
GD1β
GM1α
GM2α
O-Acetylated GT3
GP1c
GQ1c
GT1c
GT2
GT3
O-Acetylated GD3
N-Acetyl-galactosaminyl GD1a
Fucosyl GM1
GD1c
N-Acetyl-galactosaminyl GM1b
GM1b
Siat8e
Acatn
2 ...
|
|
hsa00620
|
|
Pyruvate metabolism
|
|
C15973 (Enzyme N6-(dihydrolipoyl)lysine)
C15972 (Enzyme N6-(lipoyl)lysine)
C16255 ([Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine)
C05125 (2-(alpha-Hydroxyethyl)thiamine diphosphate)
C03248 ...
|
PYRUVATE METABOLISM
Nicotinate and nicotinamide metabolism
1.2.4.1
Citrate cycle
Glycine, serine and threonine metabolism
Glycolysis
4.1.1.31
4.1.1.32
4.1.1.38
4.1.1.49
2.7.9.1
2.7.9.2
2.7.1.40
1.2.1 ...
|
|
hsa00630
|
|
Glyoxylate and dicarboxylate metabolism
|
|
C00898 ((R,R)-Tartaric acid)
C00036 (Oxaloacetate)
C00158 (Citrate)
C00149 ((S)-Malate)
C04348 (L-Malyl-CoA)
C03548 (trans-2,3-Epoxysuccinate)
C00552 (meso-Tartaric acid)
C03459 (2-Hydroxy-3-oxosuccinate)
C00975 ...
|
5.3.1.22
4.2.1.3
2.2.1.5
2.3.3.12
2.3.3.7
4.1.3.13
4.1.3.16
4.1.3.1
3.5.1.68
3.5.1.56
3.5.1.49
3.5.1.31
3.5.1.10
3.5.1.9
3.5.1.8
4.2.1.3
1.2.1.17
4.1.1.8
1.1.99.14
1.1.3.15
1.1.1.79
1.1.1.26
6.2.1.8
2 ...
|
|
hsa00640
|
|
Propanoate metabolism
|
|
C00222 (3-Oxopropanoate)
C00804 (Propynoate)
C01013 (3-Hydroxypropanoate)
C00099 (beta-Alanine)
C00083 (Malonyl-CoA)
C00109 (2-Oxobutanoate)
C02876 (Propanoyl phosphate)
C00163 (Propanoate)
C00186 ((S)-Lactate)
C00827 ...
|
PROPANOATE METABOLISM
1.2.1.18
2.1.3.1
6.4.1.2
4.1.1.9
1.2.1.75
2.6.1.18
2.6.1.19
1.1.1.59
4.2.1.27
Pantothenate and CoA biosynthesis
Malonate semialdehyde
Propynoate
3-Hydroxy-propanoate
β-Alanine
3 ...
|
|
hsa00650
|
|
Butanoate metabolism
|
|
C03046 ((S,S)-Butane-2,3-diol)
C01769 ((S)-Acetoin)
C00810 ((R)-Acetoin)
C03044 ((R,R)-Butane-2,3-diol)
C06010 ((S)-2-Acetolactate)
C00022 (Pyruvate)
C00042 (Succinate)
C00122 (Fumarate)
C01384 (Maleic ...
|
Biosynthesis of type II polyketide backbone
4.2.1.27
1.1.1.30
3.1.1.22
2.8.3.5
6.2.1.16
4.1.3.4
2.3.3.10
2.3.1.9
1.1.1.157
1.1.1.35
1.1.1.36
5.1.2.3
2.3.1.304
3.1.1.75
4.2.1.17
4.2.1.55
5.3.3.3
1.1.1.61
2 ...
|
|
hsa00670
|
|
One carbon pool by folate
|
|
C00504 (Folate)
C00415 (Dihydrofolate)
C03479 (Folinic acid)
C00143 (5,10-Methylenetetrahydrofolate)
C00440 (5-Methyltetrahydrofolate)
C00664 (5-Formiminotetrahydrofolate)
C00234 (10-Formyltetrahydrofolate)
C00445 ...
|
ONE CARBON POOL BY FOLATE
Folate biosynthesis
2.1.2.5
2.1.2.4
2.1.2.2
4.3.1.4
1.5.1.15
1.5.1.3
1.5.1.3
2.1.2.5
1.5.1.54
3.5.4.9
1.5.1.5
Folate
7,8-Dihydrofolate
5-Formyl-THF
5,10-Methylene-THF
5-Methyl-THF
5-Formimino-THF
6 ...
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|
hsa00730
|
|
Thiamine metabolism
|
|
C00082 (L-Tyrosine)
C15809 (Iminoglycine)
C11437 (1-Deoxy-D-xylulose 5-phosphate)
C15814 (Thiocarboxy-[sulfur-carrier protein])
C15813 (Adenylyl-[sulfur-carrier protein])
C15812 ([Enzyme]-S-sulfanylcysteine)
C15811 ...
|
L-Tyrosine
Iminoglycine
1-Deoxy-D-xylulose 5-phosphate
[ThiS]-COSH
[ThiS]-CO-AMP
[IscS]-SSH
[IscS]-SH
L-Cysteine
[ThiS]-COOH
Glycine metabolism
Tyrosine biosynthesis
THIAMINE METABOLISM
Glycolysis
Purine ...
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|
hsa00740
|
|
Riboflavin metabolism
|
|
C15556 (L-3,4-Dihydroxybutan-2-one 4-phosphate)
C00199 (D-Ribulose 5-phosphate)
C00044 (GTP)
C01304 (2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one)
C01268 (5-Amino-6-(5'-phosphoribosylamino)uracil)
C04454 ...
|
3,4-Dihydroxy-2-butanone 4-phosphate
Ribulose 5-phosphate
Pentose phosphate pathway
RIBOFLAVIN METABOLISM
Pentose and glucuronate interconversions
Purine metabolism
GTP
2,5-Diamino-6-(5-phospho-D-ribosylamino)-pyrimidin-4(3H)-one
5-Amino-6-(5-phospho-D-ribosylamino)uracil
5-Amino-6-(5-phospho-D-ribitylamino)uracil
6 ...
|
|
hsa00750
|
|
Vitamin B6 metabolism
|
|
C00118 (D-Glyceraldehyde 3-phosphate)
C00117 (D-Ribose 5-phosphate)
C07335 (2-Amino-3-oxo-4-phosphonooxybutyrate)
C00232 (Succinate semialdehyde)
C01215 (2-(Acetamidomethylene)succinate)
C01270 (3-Hydroxy-2-methylpyridine-5-carboxylate)
C04604 ...
|
D-Glyceraldehyde 3-phosphate
D-Ribose 5-phosphate
4.3.3.6
Glycolysis
Pentose phosphate pathway
2-Amino-3-oxo-4-phosphonobutanoate
2.6.1.54
VITAMIN B METABOLISM
Pentose phosphate pathway
Glyoxylate and ...
|
|
hsa00760
|
|
Nicotinate and nicotinamide metabolism
|
|
C06178 (1-Methylpyrrolinium)
C15523 (2,6-Dihydroxynicotinate)
C00022 (Pyruvate)
C00163 (Propanoate)
C03652 ((2R,3S)-2,3-Dimethylmalate)
C00922 (2,3-Dimethylmaleate)
C02295 (Methylitaconate)
C02930 (2-Methyleneglutarate)
C16390 ...
|
Pyruvate metabolism
C5-Branched dibasic acid metabolism
4.1.3.32
4.2.1.85
5.3.3.6
5.4.99.4
1.1.1.291
3.5.2.18
1.3.7.1
1.17.3.3
1.14.13.10
3.7.1.19
1.5.99.14
1.5.3.5
1.5.3.6
1.4.1.21
3.6.1.22
NICOTINATE ...
|
|
hsa00770
|
|
Pantothenate and CoA biosynthesis
|
|
C03688 (Apo-[acyl-carrier protein])
C00022 (Pyruvate)
C04272 ((R)-2,3-Dihydroxy-3-methylbutanoate)
C00141 (3-Methyl-2-oxobutanoic acid)
C00183 (L-Valine)
C00966 (2-Dehydropantoate)
C00522 ((R)-Pantoate)
C00864 ...
|
Apo-[acp]
PANTOTHENATE AND CoA BIOSYNTHESIS
Alanine, aspartate and glutamate metabolism
Propanoate metabolism
Glycolysis
Cysteine and methionine metabolism
β-Alanine metabolism
Pyruvate
(R)-2,3-Dihydroxy-3-methylbutanoate
3-Methyl-2-oxobutanoate
L-Valine
2-Dehydropantoate
(R)-Pantoate
(R)-Pantothenate
L-Cysteine
(R)-4'-Phospho-pantothenoyl-L-cysteine
...
|
|
hsa00780
|
|
Biotin metabolism
|
Biotin (vitamin H or vitamin B7) is the essential cofactor of biotin-dependent carboxylases, such as pyruvate carboxylase and acetyl-CoA carboxylase. Mammals cannot synthesize biotin, while in bacteria ...
|
C02656 (Pimelate)
C01063 (Pimeloyl-CoA)
C01092 (8-Amino-7-oxononanoate)
C01909 (Dethiobiotin)
C01037 (7,8-Diaminononanoate)
C00120 (Biotin)
C00047 (L-Lysine)
C05552 (Biocytin)
C01894 (Biotinyl-CoA)
C05921 ...
|
Tropane, piperidine and pyridine alkaloid biosynthesis
BIOTIN METABOLISM
Lysine degradation
Pimelate
Pimeloyl-CoA
8-Amino-7-oxononanoate
Dethiobiotin
7,8-Diamino-nonanoate
Biotin
L-Lysine
N6-D-Biotinyl-L-lysine
Biotinyl-CoA
Biotinyl-5'-AMP
Holo-[carboxylase]
6 ...
|
|
hsa00785
|
|
Lipoic acid metabolism
|
|
C16241 ((R)-Lipoate)
C16238 (Lipoyl-AMP)
C22160 ([Lipoyl-carrier protein E2]-N6-octanoyl-L-lysine)
C15972 (Enzyme N6-(lipoyl)lysine)
C22159 ([Glycine cleavage system H]-N6-octanoyl-L-lysine)
C06423 (Octanoic ...
|
2.3.1.181
LIPOIC ACID METABOLISM
Fatty acid biosynthesis
2.8.1.8
2.3.1.181
( Biosynthesis )
( Salvage )
LipM
Oxo-acid dehydrogenase complexes (E2 subunit)
Glycine cleavage system (H protein)
LIPT1
LAE
6 ...
|
|
hsa00790
|
|
Folate biosynthesis
|
|
C11355 (4-Amino-4-deoxychorismate)
C00251 (Chorismate)
C00044 (GTP)
C04895 (7,8-Dihydroneopterin 3'-triphosphate)
C03684 (6-Pyruvoyltetrahydropterin)
C04244 (6-Lactoyl-5,6,7,8-tetrahydropterin)
C00272 ...
|
4-Amino-4-deoxychorismate
Chorismate
FOLATE BIOSYNTHESIS
One carbon pool by folate
Purine metabolism
GTP
7,8-Dihydroneopterin 3'-P
6-Pyruvoyl-5,6,7,8-tetrahydropterin
6-Lactoyl-5,6,7,8-tetrahydropterin
5 ...
|
|
hsa00830
|
|
Retinol metabolism
|
|
C05917 (Iodopsin)
C00473 (Retinol)
C00376 (Retinal)
C02094 (beta-Carotene)
C00777 (Retinoate)
C02075 (Retinyl ester), C02588 (Retinyl palmitate)
C00899 (11-cis-Retinol)
C02110 (11-cis-Retinal)
C16682 (9-cis-Retinol)
C16681 ...
|
Iodopsin
RETINOL METABOLISM
all-trans-Retinol (Vitamine A)
ADH
all-trans-Retinal
1.13.11.63
β-Carotene
1.2.1.36
all-trans-Retinoate
1.2.3.1
all-trans-Retinyl ester
LRAT
11-cis-Retinol
11-cis Retinal
RDH
9-cis-Retinol
9-cis-Retinal
9-cis-Retinoate
all-trans-13 ...
|
|
hsa00860
|
|
Porphyrin metabolism
|
Porphyrins are a group of chemical compounds with the backbone ring structure consisting of four linked pyrrole units. Metal complexes of porphyrins, as well as those of corrinoids with the one-carbon ...
|
C05774 (Cobinamide)
C16243 (Cobalt-precorrin 5B)
C16244 (Cobalt-precorrin 7)
C15670 (Heme A)
C15672 (Heme O)
C00037 (Glycine)
C04122 (D-1-Aminopropan-2-ol O-phosphate)
C12147 (L-Threonine O-3-phosphate)
C11851 ...
|
Ala, Asp and Glu metabolism
3.1.1.82
Cobinamide
Co-precorrin 5B
Co-precorrin 7
Heme A
Heme O
Glycine
1.3.1.75
1.3.98.3
(R)-1-Amino-propan-2-yl phosphate
L-Threonine phosphate
Zn-Bacterio-chlorophyll a
BchJ
1 ...
|
|
hsa00900
|
|
Terpenoid backbone biosynthesis
|
Terpenoids, also known as isoprenoids, are a large class of natural products consisting of isoprene (C5) units. There are two biosynthetic pathways, the mevalonate pathway [MD:M00095] and the non-mevalonate ...
|
C05859 (ditrans,polycis-Polyprenyl diphosphate)
C06081 (Polyprenol)
C00022 (Pyruvate)
C00024 (Acetyl-CoA)
C00332 (Acetoacetyl-CoA)
C00118 (D-Glyceraldehyde 3-phosphate)
C11434 (2-C-Methyl-D-erythritol ...
|
MEP/DOXP pathway
Mevalonate pathway
Dehydro dolichol-PP
ditrans,polycis-Polyprenol
Glycolysis
TERPENOID BACKBONE BIOSYNTHESIS
pyruvate
Acetyl-CoA
Acetoacetyl-CoA
D-Glyceraldehyde 3-phosphate
2-C-Methyl-D-erythritol ...
|
|
hsa00910
|
|
Nitrogen metabolism
|
The biological process of the nitrogen cycle is a complex interplay among many microorganisms catalyzing different reactions, where nitrogen is found in various oxidation states ranging from +5 in nitrate ...
|
C00058 (Formate)
C00488 (Formamide)
C00014 (Ammonia)
C00192 (Hydroxylamine)
C06058 (Nitroalkane)
C00887 (Nitrous oxide)
C00533 (Nitric oxide)
C00088 (Nitrite)
C00244 (Nitrate)
C00726 (Nitrile)
C01417 (Cyanate)
C01563 ...
|
Formate
Formamide
3.5.1.49
Ammonia
Hydroxylamine
Nitroalkane
1.7.2.6
1.9.6.1
1.7.99.-
1.7.7.2
1.13.12.16
1.7.3.1
1.7.1.10
1.7.99.1
1.7.2.2
1.7.1.4
1.7.7.1
1.7.2.1
1.18.6.1
1.19.6.1
1.7.2.4
1.7.2.5
1.14 ...
|
|
hsa00920
|
|
Sulfur metabolism
|
Sulfur is an essential element for life and the metabolism of organic sulfur compounds plays an important role in the global sulfur cycle. Sulfur occurs in various oxidation states ranging from +6 in sulfate ...
|
C00059 (Sulfate)
C00094 (Sulfite)
C00283 (Hydrogen sulfide)
C00224 (Adenylyl sulfate)
C00054 (Adenosine 3',5'-bisphosphate)
C00053 (3'-Phosphoadenylyl sulfate)
C11142 (Dimethyl sulfone)
C11145 (Methanesulfonic ...
|
SULFUR METABOLISM
Sulfate
Sulfite
1.8.2.1
1.8.3.1
1.8.7.1
1.8.1.2
Asr
Sulfide
3.1.3.7
2.7.1.25
3.6.2.1
2.7.7.5
2.7.7.4
APS
PAP
PAPS
3.6.2.2
1.8.4.8
1.8.99.2
1.8.4.9
Dimethylsulfone
Methane-sulfonate
1 ...
|