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ENTRY	nt06181
Name	Salmonella
Category	Disease view; Bacterial infection
Pathway	hsa05132 Salmonella infection
Disease	H00111 Typhoid fever
Display	drug-target relation   disease type

MAPK signaling N01119        (RAC1,CDC42) → PAK1 → RAF → MEK → ERK N01120    SptP ⊣ (RAC1,CDC42) N01134    SopB → CDC42 N01121                    SpvC ⊣ ERK   WNT signaling N00056    WNT → (FZD+LRP5/6) → (DVL+FRAT) ⊣ (GSK3B+AXIN+APC) ⊣ CTNNB1 → TCF/LEF ⇒ (MYC,CCND1) N01124                AvrA → CTNNB1 → TCF/LEF ⇒ MYC   TNF signaling N00446    TNF → TNFRSF1A → (RIPK1+TRADD+TRAF2.. → (TAK1+TAB1/2) → MKK4/7 → JNK → AP1 N01125                AvrA ⊣ MAP2K7 N00151    TNF → TNFRSF1A → (RIPK1+TRADD+TRAF2.. → (TAB1/2/3+TAK1) → IKK → NFKBIA → NFKB N01114    SseK3 ⊣ TNFRSF1A N01113        SseK1 ⊣ (RIPK1+TRADD+TRAF2.. N01117                GogB ⊣ SKP1 → NFKBIA N01116                    SseL ⊣ NFKBIA N01123                    AvrA ⊣ NFKBIA N01118                SpvD ⊣ XPO2 → (KPNA1+KPNA3) → NFKB N01122                        PipA ⊣ RELA   NLR signaling N00940            (NOD1,NOD2) → RIPK2 → IKK → NFKBIA → NFKB N01112    SopE/E2 → CDC42 → NOD1 → RIPK2 → IKK → NFKBIA → NFKB N00742        (NLRP3+PYCARD) → CASP1 → (IL1B,IL18,IL33) N01127    SopE → RAC1 → CASP1 → (IL1B,IL18) N01126        SipB → CASP1 → (IL1B,IL18)   Cytoskeletal regulation N01072    FN1 → (ITGA+ITGB) → PTK2 → ARHGEF28 → RHOA N01130                SopB → RHOA → ROCK2 → MLC N01131                SopE/E2 → RHOA → ROCK2 → FHOD1 N01068    FN1 → (ITGA+ITGB) → (SRC,PTK2) → (PXN,CRK+BCAR1) → (DOCK1+ELMO1) → RAC N01128                    SopE → RAC1 → (WASF+ABI1+HSPC300.. → ARP2/3 → (ACTB,ACTG1) N00951    FN1 → (ITGA+ITGB) → RHOG → (DOCK1+ELMO) → RAC N01133    SopB → ARHGEF26 → RHOG → ELMO N01132        SopE/E2 → RHOG → ELMO N01066                ARNO → ARF6 → ARF1 → (WASF+ABI1+HSPC300.. → ARP2/3 → (ACTB,ACTG1) N01129    SopB → (PIK3CA/B/G/D,PIK3.. → PIP3 → ARNO → ARF6 → ARF1 → (WASF+ABI1+HSPC300.. → ARP2/3 → (ACTB,ACTG1) N01304        (ANXA2+S100A10) = AHNAK = (ACTB,ACTG1) N01305    (SopB,SopE) → (ANXA2+S100A10) = AHNAK = (ACTB,ACTG1)   Membrane trafficking N01302    (RABGEF1+RABEP1) → RAB5 → (PIK3C3+PIK3R4) → PI3P → EEA1 N01303    SopB → RAB5 → PIK3C3 → PI3P N01295        RAB7 = RILP = OSBPL1A = (DYNC+DYNL+DCTN+AC.. = (TUBA+TUBB) N01296    SopD2 ⊣ RAB7 N01297    BORCS = ARL8 = PLEKHM2 = (KIF5+KLC) = (TUBA+TUBB) N01298        SifA → PLEKHM2 = (KIF5+KLC) = (TUBA+TUBB) N01299            PipB2 → (KIF5+KLC) = (TUBA+TUBB) N01300    ARL8B = PLEKHM1 = RAB7 = HOPS N01301    SifA = PLEKHM1 = RAB7 = HOPS