Network variation - WNT signaling (cancer)
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ENTRY
nt06215
Name
WNT signaling (cancer)
Category
Disease view; Cancer signaling
Display
drug-target relation
disease type
N00056
WNT
→
(FZD+LRP5/6)
→
(DVL+FRAT)
⊣
(GSK3B+AXIN+APC)
⊣
CTNNB1
→
TCF/LEF
⇒
(MYC,CCND1)
N00059
WNT
→
(
FZD7*
+
LRP5/6
)
→
(
DVL
+
FRAT
)
⊣
(
GSK3B
+
AXIN
+
APC
)
⊣
CTNNB1
→
TCF/LEF
⇒
(
MYC
,
CCND1
)
N00060
WNT
→
(
FZD
+
LRP6*
)
→
(
DVL
+
FRAT
)
⊣
(
GSK3B
+
AXIN
+
APC
)
⊣
CTNNB1
→
TCF/LEF
⇒
(
MYC
,
CCND1
)
N00175
LANA
⊣
GSK3B
⊣
CTNNB1
→
TCF/LEF
⇒
CCND1
N00242
(
GSK3B
+
APC
)
⌿
AXIN*
⌿
CTNNB1
→
TCF/LEF
⇒
(
MYC
,
CCND1
)
N00057
(
GSK3B
+
AXIN
)
⌿
APC*
⌿
CTNNB1
→
TCF/LEF
⇒
(
BIRC5
,
MYC
,
CCND1
)
N00058
(
GSK3B
+
AXIN
+
APC
)
⌿
CTNNB1*
→
TCF/LEF
⇒
(
BIRC5
,
MYC
,
CCND1
)
N00061
CDH1*
⌿
CTNNB1
→
TCF/LEF
⇒
(
MYC
,
CCND1
)
N00257
CDH1*
⌿
CTNNB1
→
TCF/LEF
⇒
(
MYC
,
CCND1
)
N00258
CDH1*
⌿
CTNNB1
→
TCF/LEF
⇒
(
MYC
,
CCND1
)