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ENTRY	nt06250
Name	DNA adduct formation (cancer)
Category	Disease view; Cancer signaling
Display	drug-target relation   disease type

N01369    4-ABP − CYP1A2 ⇉ NAT1 → N-OAc-ABP = DNA N01370    PhIP − CYP1A2 ⇉ NAT2 → N-OAc-PhIP = DNA N01371    PhIP − CYP1A2 ⇉ SULT1A → N-sulfonyloxy-PhIP = DNA N01372    IQ − CYP1A2 ⇉ (NAT1,NAT2) → N-Acetoxy-IQ = DNA N01373    MeIQx − CYP1A2 ⇉ NAT2 → N-Acetoxy-MeIQx = DNA N01374    BaP − (CYP1A1,CYP1B1) ⇉ EPHX1 ⇉ (CYP1A1,CYP1B1) → BPDE = DNA N01375    DMBA − CYP1A1 ⇉ EPHX1 ⇉ CYP1A1 → DMBADE = DNA N01376    Melphalan = DNA N01377    Thiotepa = DNA N01378    AFB1 − (CYP3A4,CYP1A2) → AFB1-exo-8,9-epoxi.. = DNA N01379    NNK − (CYP2A6,CYP2A13) → C19563 → C19564 = DNA N01380    NNK − (CYP2A6,CYP2A13) → C19566 → C19568 → C20302 = DNA N01381    NNK − (AKR1C2,CBR1,HSD11.. ⇉ (CYP2A6,CYP2A13) → C19577 → C19568 → C20302 = DNA N01382    NNK − (AKR1C2,CBR1,HSD11.. ⇉ (CYP2A6,CYP2A13) → C19580 → C19581 = DNA N01383    NMDA − CYP2E1 → C20301 → C20302 = DNA N01384    EO = DNA N01385    VC − CYP2E1 → CEO = DNA N01386    DCE − GST → C20304 → C14874 = DNA N01387    SM = DNA