[ Network menu | Network entry | Edit Network | Help ]

ENTRY	nt06506
Name	Double-strand break repair
Category	Pathway view; Replication and repair
Pathway	hsa03440 hsa03450
Disease	H00094 Immunodeficiency associated with DNA repair defects
Display	drug-target relation   disease type

N01439        ATLD1     NBSLD     NBS/AA     AT/CLL     MRT38     RIDDLE   N01446        SCKL2     WRN/RecQ     SCKL8     PFBMFT6   N01451        SCKL1/FCTS   N01452        BC/PNCA4/BROVCA1/FANCS     BC     BC/PNCA2/BROVCA2/FANCD     BC/PNCA3/FANCN     BC/FANCR     BROVCA3/FANCO     BROVCA4     FANCU/POF17     BC/CMM6     BC/NHL     NHL     ATLD2     MDPL   N01447        MGRISCE1/BLM/RecQ     MGRISCE2/PEOB5   N01448        FANCP   N01449        DKCA4/PFBMFT3   N01450        DFNA70     IMD54     MGORS8   N01445      N01467        SCID/OMENN     SCID/OMENN     SCID     SCID/OMENN     LIG4     SSMED     SCID

ATLD1	H02014	Ataxia-telangiectasia-like syndrome
NBSLD	H01344	Nijmegen breakage syndrome
NBS	H01344	Nijmegen breakage syndrome
AA	H01132	Aplastic anemia
AT	H00064	Ataxia telangiectasia
CLL	H00005	Chronic lymphocytic leukemia
MRT38	H00768	Autosomal recessive intellectual developmental disorder
RIDDLE	H00962	RIDDLE syndrome
SCKL2	H00992	Seckel syndrome
WRN	H01733	Werner syndrome
RecQ	H00296	Defects in RecQ helicases
SCKL8	H00992	Seckel syndrome
PFBMFT6	H02569	Pulmonary fibrosis and/or bone marrow failure, telomere-related
SCKL1	H00992	Seckel syndrome
FCTS	H02576	Familial cutaneous telangiectasia and cancer syndrome
BC	H00031	Breast cancer
PNCA4	H00019	Pancreatic cancer
BROVCA1	H02531	Familial breast-ovarian cancer
FANCS	H00238	Fanconi anemia
PNCA2	H00019	Pancreatic cancer
BROVCA2	H02531	Familial breast-ovarian cancer
FANCD	H00238	Fanconi anemia
PNCA3	H00019	Pancreatic cancer
FANCN	H00238	Fanconi anemia
FANCR	H00238	Fanconi anemia
BROVCA3	H02531	Familial breast-ovarian cancer
FANCO	H00238	Fanconi anemia
BROVCA4	H02531	Familial breast-ovarian cancer
FANCU	H00238	Fanconi anemia
POF17	H00627	Premature ovarian failure
CMM6	H00038	Melanoma
NHL	H02418	Non-Hodgkin lymphoma
ATLD2	H02014	Ataxia-telangiectasia-like syndrome
MDPL	H01623	MDPL syndrome
MGRISCE1	H02492	Microcephaly, growth restriction, and increased sister chromatid exchange
BLM	H01346	Bloom syndrome
MGRISCE2	H02492	Microcephaly, growth restriction, and increased sister chromatid exchange
PEOB5	H01395	Autosomal recessive progressive external ophthalmoplegia
FANCP	H00238	Fanconi anemia
DKCA4	H00507	Dyskeratosis congenita
PFBMFT3	H02569	Pulmonary fibrosis and/or bone marrow failure, telomere-related
DFNA70	H00604	Deafness, autosomal dominant
IMD54	H00094	Immunodeficiency associated with DNA repair defects
MGORS8	H01889	Meier-Gorlin syndrome
SCID	H00092	T-B-Severe combined immunodeficiency
OMENN	H01244	T+B+Severe combined immunodeficiencies (SCIDs)
	H02554	Omenn syndrome
LIG4	H02015	LIG4 syndrome
SSMED	H02578	Short stature, microcephaly, and endocrine dysfunction