KEGG    Network variation - Double-strand break repair
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ENTRYnt06506
NameDouble-strand break repair
CategoryPathway view; Replication and repair
Pathwayhsa03440 hsa03450
DiseaseH00094 Immunodeficiency associated with DNA repair defects
Display drug-target relation   disease type
N01439   
    ATLD1
    NBSLD
    NBS/AA
    AT/CLL
    MRT38
    RIDDLE
 
N01446   
    SCKL2
    WRN/RecQ
    SCKL8
    PFBMFT6
 
N01451   
    SCKL1/FCTS
 
N01452   
    BC/PNCA4/BROVCA1/FANCS
    BC
    BC/PNCA2/BROVCA2/FANCD
    BC/PNCA3/FANCN
    BC/FANCR
    BROVCA3/FANCO
    BROVCA4
    FANCU/POF17
    BC/CMM6
    BC/NHL
    NHL
    ATLD2
    MDPL
 
N01447   
    MGRISCE1/BLM/RecQ
    MGRISCE2/PEOB5
 
N01448   
    FANCP
 
N01449   
    DKCA4/PFBMFT3
 
N01450   
    DFNA70
    IMD54
    MGORS8
 
N01445   
 
N01467   
    SCID/OMENN
    SCID/OMENN
    SCID
    SCID/OMENN
    LIG4
    SSMED
    SCID

ATLD1H02014Ataxia-telangiectasia-like syndrome
NBSLDH01344Nijmegen breakage syndrome
NBSH01344Nijmegen breakage syndrome
AAH01132Aplastic anemia
ATH00064Ataxia telangiectasia
CLLH00005Chronic lymphocytic leukemia
MRT38H00768Autosomal recessive intellectual developmental disorder
RIDDLEH00962RIDDLE syndrome
SCKL2H00992Seckel syndrome
WRNH01733Werner syndrome
RecQH00296Defects in RecQ helicases
SCKL8H00992Seckel syndrome
PFBMFT6H02569Pulmonary fibrosis and/or bone marrow failure, telomere-related
SCKL1H00992Seckel syndrome
FCTSH02576Familial cutaneous telangiectasia and cancer syndrome
BCH00031Breast cancer
PNCA4H00019Pancreatic cancer
BROVCA1H02531Familial breast-ovarian cancer
FANCSH00238Fanconi anemia
PNCA2H00019Pancreatic cancer
BROVCA2H02531Familial breast-ovarian cancer
FANCDH00238Fanconi anemia
PNCA3H00019Pancreatic cancer
FANCNH00238Fanconi anemia
FANCRH00238Fanconi anemia
BROVCA3H02531Familial breast-ovarian cancer
FANCOH00238Fanconi anemia
BROVCA4H02531Familial breast-ovarian cancer
FANCUH00238Fanconi anemia
POF17H00627Premature ovarian failure
CMM6H00038Melanoma
NHLH02418Non-Hodgkin lymphoma
ATLD2H02014Ataxia-telangiectasia-like syndrome
MDPLH01623MDPL syndrome
MGRISCE1H02492Microcephaly, growth restriction, and increased sister chromatid exchange
BLMH01346Bloom syndrome
MGRISCE2H02492Microcephaly, growth restriction, and increased sister chromatid exchange
PEOB5H01395Autosomal recessive progressive external ophthalmoplegia
FANCPH00238Fanconi anemia
DKCA4H00507Dyskeratosis congenita
PFBMFT3H02569Pulmonary fibrosis and/or bone marrow failure, telomere-related
DFNA70H00604Deafness, autosomal dominant
IMD54H00094Immunodeficiency associated with DNA repair defects
MGORS8H01889Meier-Gorlin syndrome
SCIDH00092T-B-Severe combined immunodeficiency
OMENNH01244T+B+Severe combined immunodeficiencies (SCIDs)
H02554Omenn syndrome
LIG4H02015LIG4 syndrome
SSMEDH02578Short stature, microcephaly, and endocrine dysfunction