KEGG Alzheimer disease - Homo sapiens (human)
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  • nt06410 Calcium signaling
    • N01002 Mutation-caused aberrant Abeta to mGluR5-Ca2+ -apoptotic pathway
    • N01008 Mutation-caused aberrant PSEN1 to mGluR5-Ca2+ -apoptotic pathway
    • N01007 Mutation-caused aberrant PSEN to mGluR5-Ca2+ -apoptotic pathway
    • N01001 Mutation-caused aberrant Abeta to mAchR-Ca2+ -apoptotic pathway
    • N01004 Mutation-caused aberrant Abeta to VGCC-Ca2+ -apoptotic pathway
    • N01006 Mutation-caused aberrant Abeta to VGCC-Ca2+ -apoptotic pathway
    • N01003 Mutation-caused aberrant Abeta to transport of calcium
  • nt06420 Ubiquitin-proteasome system
    • N01060 Mutation-caused aberrant Abeta to 26S proteasome-mediated protein degradation
  • nt06412 Unfolded protein response (UPR) signaling
    • N01010 Mutation-caused aberrant PSEN1 to PERK-ATF4 signaling pathway
    • N01012 Mutation-caused aberrant PSEN1 to IRE1a-XBP1 signaling pathway
    • N01014 Mutation-caused aberrant Abeta to IRE1a-JNK signaling pathway
    • N01016 Mutation-caused aberrant PSEN1 to ATF6-mediated transcription
  • nt06414 Apoptosis
    • N01005 Mutation-caused aberrant Abeta to crosstalk between extrinsic and intrinsic apoptotic pathways
  • nt06417 AGE-RAGE signaling
    • N00996 Mutation-caused aberrant Abeta to AGE-RAGE signaling pathway
  • nt06418 Oxidative phosphorylation
    • N00997 Mutation-caused aberrant Abeta to electron transfer in Complex I
    • N00999 Mutation-caused aberrant Abeta to electron transfer in Complex IV
  • nt06419 Microtubule-based transport
    • N01017 Mutation-caused aberrant PSEN1 to anterograde axonal transport
    • N01018 Mutation-caused aberrant Abeta to anterograde axonal transport