| Entry |
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|---|
| Name |
Chlorprothixene hydrochloride (JAN) |
|---|
| Formula |
C18H18ClNS. HCl
|
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| Exact mass |
351.0615
|
|---|
| Mol weight |
352.3212
|
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antipsychotic, Dopamine receptor antagonist |
|---|
| Comment |
Thioxanthene derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AF Thioxanthene derivatives
N05AF03 Chlorprothixene
D02162 Chlorprothixene hydrochloride (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG00894 Chlorprothixene
D02162 Chlorprothixene hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD1
D02162 Chlorprothixene hydrochloride (JAN)
DRD2
D02162 Chlorprothixene hydrochloride (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG00894 Chlorprothixene
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 22
1 C8x C 22.8269 -17.0418
2 C8x C 22.8269 -18.4444
3 C8x C 24.0415 -19.1457
4 C8y C 25.2563 -18.4444
5 C8y C 25.2563 -17.0418
6 C8x C 24.0415 -16.3405
7 S2x S 26.4710 -19.1457
8 C8y C 27.6857 -18.4444
9 C8y C 27.6857 -17.0418
10 C8y C 26.4710 -16.3405
11 C8x C 28.9006 -19.1457
12 C8x C 30.1152 -18.4444
13 C8y C 30.1152 -17.0418
14 C8x C 28.9006 -16.3405
15 C2b C 26.4710 -14.9378
16 C1b C 27.6878 -14.2353
17 C1b C 28.8866 -14.9276
18 N1c N 30.0757 -14.2411
19 C1a C 31.2694 -14.9306
20 C1a C 30.0759 -12.8341
21 X Cl 31.3340 -16.3382
22 X Cl 33.3900 -17.7100
BOND 23
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 9 14 2
17 10 15 2
18 15 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 18 20 1
23 13 21 1
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