| Entry |
|
|---|
| Name |
Betahistine hydrochloride (USP);
Serc (TN) |
|---|
| Formula |
C8H12N2. 2HCl
|
|---|
| Exact mass |
208.0534
|
|---|
| Mol weight |
209.1162
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01556 Histamine receptor H3 antagonist
|
|---|
| Remark |
| Product (DG01004): | D01592<JP> |
|
|---|
| Efficacy |
Antivertigo, Vasodilator, Antihistaminic |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07C ANTIVERTIGO PREPARATIONS
N07CA Antivertigo preparations
N07CA01 Betahistine
D03102 Betahistine hydrochloride (USP)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01556 Histamine receptor H3 antagonist
DG01004 Betahistine
D03102 Betahistine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D03102 Betahistine hydrochloride (USP)
HRH3
D03102 Betahistine hydrochloride (USP)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01556 Histamine receptor H3 antagonist
DG01004 Betahistine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 12
1 C8x C 25.5193 -14.6975
2 C8x C 25.5193 -13.2961
3 N5x N 24.3027 -12.5954
4 C8y C 23.0933 -13.2961
5 C8x C 23.0933 -14.6975
6 C8x C 24.3027 -15.3982
7 C1b C 21.8884 -12.6023
8 C1b C 20.6781 -13.3030
9 N1b N 19.4678 -12.6095
10 C1a C 18.2575 -13.3102
11 X Cl 28.9800 -13.9300
12 X Cl 28.9800 -13.9300
BOND 10
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 6 1 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
BRACKET 1 27.3700 -14.6300 27.3700 -13.0900
1 29.8200 -13.0900 29.8200 -14.6300
1 2
ORIGINAL 1 11
REPEAT 1 12
|
|---|
