| Entry |
|
|---|
| Name |
Indoramin hydrochloride (USAN) |
|---|
| Formula |
C22H25N3O. HCl
|
|---|
| Exact mass |
383.1764
|
|---|
| Mol weight |
383.9143
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG01739 Peripherally-acting antiadrenergic
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, alpha1-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C02 ANTIHYPERTENSIVES
C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
C02CA Alpha-adrenoreceptor antagonists
C02CA02 Indoramin
D04532 Indoramin hydrochloride (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00254 Indoramin
D04532 Indoramin hydrochloride
DG01739 Peripherally-acting antiadrenergic
DG00254 Indoramin
D04532 Indoramin hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D04532 Indoramin hydrochloride (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00254 Indoramin
DG01739 Peripherally-acting antiadrenergic
DG00254 Indoramin
|
|---|
| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 X Cl 33.6000 -17.6400
2 C8x C 17.0100 -18.2700
3 C8x C 17.0100 -19.6700
4 C8x C 18.2000 -20.3700
5 C8y C 19.4600 -19.6700
6 C8y C 19.4600 -18.2700
7 C8x C 18.2000 -17.5700
8 N4x N 20.7900 -20.0900
9 C8x C 21.5600 -18.9700
10 C8y C 20.7900 -17.8500
11 C1b C 20.7900 -16.4500
12 C1b C 21.9800 -15.7500
13 N1y N 23.1700 -16.4500
14 C1x C 23.1700 -17.8500
15 C1x C 24.4300 -18.5500
16 C1y C 25.6200 -17.8500
17 C1x C 25.6200 -16.4500
18 C1x C 24.4300 -15.7500
19 N1b N 26.8100 -18.5500
20 C5a C 28.0000 -17.8500
21 C8y C 29.1900 -18.5500
22 O5a O 28.0000 -16.4500
23 C8x C 29.1900 -19.9500
24 C8x C 30.4500 -20.6500
25 C8x C 31.6400 -19.9500
26 C8x C 31.6400 -18.5500
27 C8x C 30.4500 -17.8500
BOND 29
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 5 8 1
8 8 9 1
9 9 10 2
10 6 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 13 18 1
20 16 19 1
21 19 20 1
22 20 21 1
23 20 22 2
24 21 23 2
25 23 24 1
26 24 25 2
27 25 26 1
28 26 27 2
29 21 27 1
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