KEGG   DRUG: CisplatinHelp
Entry
D00275                      Drug                                   

Name
Cisplatin (JP17/USP/INN);
Platinol (TN)
Product
  Generic
Formula
PtCl2. 2NH3
Exact mass
298.9556
Mol weight
300.051
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antineoplastic
 DG01679  Platinum compound
Remark
Same as: C06911
Therapeutic category: 4291
ATC code: L01XA01
Product: D00275<JP/US>
Efficacy
Antineoplastic, Cell growth inhibitor
  Disease
Testicular tumors [DS:H00023]
Ovarian tumors [DS:H00027]
Bladder cancer [DS:H00022]
Comment
platinum compound
DNA alkylator
Target
DNA
Metabolism
Transporter: SLC22A2 [HSA:6582]
Interaction
Drug interaction
Structure map
map07040  Antineoplastics - alkylating agents
Other map
map01524  Platinum drug resistance
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01X OTHER ANTINEOPLASTIC AGENTS
    L01XA Platinum compounds
     L01XA01 Cisplatin
      D00275  Cisplatin (JP17/USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   429  Miscellaneous
    4291  Other Antitumors
     D00275  Cisplatin (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00275  Cisplatin
Antineoplastics [br08340.html]
 D00275
Pharmacogenomic biomarkers in FDA drug labels [br08341.html]
 Polymorphisms and germline mutations
  D00275
BRITE hierarchy
Other DBs
CAS: 15663-27-1
PubChem: 7847341
ChEBI: 27899
DrugBank: DB00515
PDB-CCD: CPT[PDBj]
NIKKAJI: J277.914E
LinkDB All DBs
KCF data Show

ATOM        5
            1   Z   Pt   34.5801  -25.8301
            2   X   Cl   35.9846  -25.8301
            3   X   Cl   34.5743  -27.2286
            4   N0  N    31.9200  -25.8300
            5   N0  N    33.8100  -24.0800
BOND        2
            1     1   2 1
            2     1   3 1

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