KEGG   DRUG: D00484Help
Entry
D00484                      Drug                                   

Name
Protriptyline hydrochloride (USP);
Vivactil (TN)
Product
  Generic
Formula
C19H21N. HCl
Exact mass
299.1441
Mol weight
299.8377
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Remark
ATC code: 
Drug group: 
Comment
norepinephrine reuptake inhibitor
Interaction
Genomic biomarker: CYP2D6 [HSA:1565]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AA Non-selective monoamine reuptake inhibitors
     N06AA11 Protriptyline
      D00484  Protriptyline hydrochloride (USP)
USP drug classification [BR:br08302]
 Antidepressants
  Tricyclics
   Protriptyline
    D00484  Protriptyline hydrochloride (USP)
BRITE hierarchy
Other DBs
CAS: 
1225-55-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        21
            1   C2x C    29.7357  -19.7447
            2   C8y C    28.8940  -18.6356
            3   C8y C    29.2291  -17.2794
            4   C1y C    30.4895  -16.7016
            5   C2x C    31.1409  -19.7699
            6   C8y C    31.7425  -17.3236
            7   C8y C    32.0289  -18.6917
            8   C8x C    28.2225  -16.3115
            9   C8x C    26.8811  -16.6994
            10  C8x C    26.5460  -18.0556
            11  C8x C    27.5527  -19.0232
            12  C8x C    33.3594  -19.1286
            13  C8x C    34.4032  -18.1946
            14  C8x C    34.1169  -16.8265
            15  C8x C    32.7861  -16.3897
            16  C1b C    30.4895  -15.3023
            17  C1b C    31.7069  -14.5992
            18  C1b C    32.9269  -15.3032
            19  N1b N    34.1529  -14.5944
            20  C1a C    35.3774  -15.3002
            21  X   Cl   37.5787  -18.3359
BOND        22
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    4  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1

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