KEGG   DRUG: D00752Help
Entry
D00752                      Drug                                   

Name
Mycophenolate mofetil (JAN/USAN);
Cellcept (TN)
Product
  Generic
MYCOPHENOLATE MOFETIL (Accord Healthcare), MYCOPHENOLATE MOFETIL (American Health Packaging), MYCOPHENOLATE MOFETIL (American Health Packaging), MYCOPHENOLATE MOFETIL (Apotex Corp), MYCOPHENOLATE MOFETIL (Ascend Laboratories), MYCOPHENOLATE MOFETIL (Cadila Healthcare Limited), MYCOPHENOLATE MOFETIL (Cardinal Health), MYCOPHENOLATE MOFETIL (Greenstone LLC), MYCOPHENOLATE MOFETIL (Mylan Pharmaceuticals), MYCOPHENOLATE MOFETIL (Qualitest Pharmaceuticals), MYCOPHENOLATE MOFETIL (Qualitest Pharmaceuticals), MYCOPHENOLATE MOFETIL (Roxane Laboratories), MYCOPHENOLATE MOFETIL (Sandoz), MYCOPHENOLATE MOFETIL (Sandoz), MYCOPHENOLATE MOFETIL (Strides Arcolab Limited), MYCOPHENOLATE MOFETIL (Teva Pharmaceuticals USA), MYCOPHENOLATE MOFETIL (UDL Laboratories), MYCOPHENOLATE MOFETIL (Zydus Pharmaceuticals (USA))
Formula
C23H31NO7
Exact mass
433.2101
Mol weight
433.4947
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Immunomodulator [DS:H00080 H00083]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Comment
prodrug, active substance: Mycophenolic acid [DR:D05096]
Target
IMP dehydrogenase inhibitor [HSA:3614 3615] [KO:K00088]
  Pathway
hsa00230  Purine metabolism
hsa00983  Drug metabolism - other enzymes  
 
Interaction
Genomic biomarker: HGPRT [HSA:3251]
Drug interaction
Structure map
Immunosuppressive agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AA Selective immunosuppressants
     L04AA06 Mycophenolic acid
      D00752  Mycophenolate mofetil (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D00752  Mycophenolate mofetil (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   IMP dehydrogenase
    Mycophenolic acid
     D00752  Mycophenolate mofetil (JAN/USAN)
BRITE hierarchy
Other DBs
CAS: 
128794-94-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        31
            1   C8y C    32.4696  -17.7102
            2   C8y C    32.4638  -16.2982
            3   C8y C    31.2561  -18.4045
            4   C1x C    33.8058  -18.1420
            5   C8y C    31.2561  -15.5981
            6   C7x C    33.7999  -15.8664
            7   C8y C    30.0424  -17.7102
            8   C1a C    31.2561  -19.8107
            9   O7x O    34.6284  -17.0042
            10  C8y C    30.0424  -16.2982
            11  O1a O    31.2561  -14.1978
            12  O6a O    34.2376  -14.5304
            13  O2a O    28.8289  -18.4045
            14  C1b C    28.8289  -15.5981
            15  C1a C    28.8289  -19.8107
            16  C2b C    27.6154  -16.2925
            17  C2c C    26.4017  -15.5923
            18  C1b C    25.1939  -16.2866
            19  C1a C    26.4076  -14.1920
            20  C1b C    23.9804  -15.5864
            21  C7a C    22.7668  -16.2749
            22  O7a O    21.5532  -15.5807
            23  O6a O    22.7610  -17.6810
            24  C1b C    20.3455  -16.2691
            25  C1b C    19.1377  -15.5747
            26  N1y N    17.9242  -16.2632
            27  C1x C    16.7164  -15.5631
            28  C1x C    17.9183  -17.6578
            29  C1x C    15.5087  -16.2575
            30  C1x C    16.7048  -18.3579
            31  O2x O    15.5728  -17.6519
BOND        33
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     3   8 1
            8     4   9 1
            9     5  10 2
            10    5  11 1
            11    6  12 2
            12    7  13 1
            13   10  14 1
            14   13  15 1
            15   14  16 1
            16   16  17 2
            17   17  18 1
            18   17  19 1
            19   18  20 1
            20   20  21 1
            21   21  22 1
            22   21  23 2
            23   22  24 1
            24   24  25 1
            25   25  26 1
            26   26  27 1
            27   26  28 1
            28   27  29 1
            29   28  30 1
            30   29  31 1
            31    6   9 1
            32    7  10 1
            33   30  31 1

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