KEGG   DRUG: Cycloserine
Entry
D00877                      Drug                                   
Name
Cycloserine (JP18/USP/INN);
Seromycin (TN)
  Abbr
DCS
Product
  Generic
CYCLOSERINE (Dr. Reddy's Laboratories)
Formula
C3H6N2O2
Exact mass
102.0429
Mol weight
102.09
Structure
Simcomp
Source
Streptomyces lavendulae [TAX:1914], Streptomyces roseochromogenes [TAX:67357]
Class
Antibacterial
 DG01966  Antitubercular
Remark
Same as: C08057
Therapeutic category: 6162
ATC code: J04AB01
Product: D00877<JP/US>
Efficacy
Antibacterial (tuberculostatic), Cell wall biosynthesis inhibitor
  Disease
Tuberculosis [DS:H00342]
Comment
Natural product
Target
D-alanine-D-alanine ligase [KO:K01921]
alanine racemase [KO:K01775]
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J04 ANTIMYCOBACTERIALS
   J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
    J04AB Antibiotics
     J04AB01 Cycloserine
      D00877  Cycloserine (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Antimycobacterials
  Antituberculars
   Cycloserine
    D00877  Cycloserine (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   616  Acting mainly on acid-fast bacteria
    6162  Cycloserines
     D00877  Cycloserine (JP18/USP/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01966  Antitubercular
   D00877  Cycloserine
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, other
   Other peptidoglycan biosynthesis inhibitor
    D00877  Cycloserine (JP18/USP/INN) <JP/US>
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, other
   Other peptidoglycan biosynthesis inhibitor
    D00877  Cycloserine (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00877  Cycloserine
Other DBs
CAS: 68-41-7
PubChem: 7847941
PDB-CCD: 4AX[PDBj]
LigandBox: D00877
NIKKAJI: J8.592H
LinkDB
KCF data

ATOM        7
            1   C1x C     7.7000  -17.0800
            2   O2x O     9.1000  -17.0800
            3   N1x N     9.5326  -15.7485
            4   C5x C     8.4000  -14.9256
            5   C1y C     7.2674  -15.7485
            6   O5x O     8.4000  -13.5100
            7   N1a N     5.9478  -15.3197
BOND        7
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     4   6 2
            7     5   7 1 #Up

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