KEGG   DRUG: D02427Help
Entry
D02427                      Drug                                   

Name
Glibornuride (USAN/INN);
Glutril (TN)
Formula
C18H26N2O4S
Exact mass
366.1613
Mol weight
366.475
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidiabetic [DS:H00409]
Remark
ATC code: 
Drug group: 
Target
sulfonylurea receptor 1 agonist [HSA:6833] [KO:K05032]
  Pathway
hsa02010  ABC transporters
hsa04911  Insulin secretion
hsa04930  Type II diabetes mellitus  
 
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - hypoglycemic agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BB Sulfonylureas
     A10BB04 Glibornuride
      D02427  Glibornuride (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC (CFTR/MRP) subfamily
    ABCC8 (sulfonylurea receptor 1)
     Glibornuride
      D02427  Glibornuride (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
26944-48-9
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        25
            1   C1z C    27.7996  -16.7237
            2   S4a S    21.5497  -20.1287
            3   N1b N    23.0422  -20.8283
            4   C5a C    24.0683  -20.1287
            5   N1b N    25.2344  -20.7350
            6   O5a O    24.0683  -18.8227
            7   C1y C    26.3071  -20.0353
            8   C1y C    27.3799  -19.2425
            9   C1y C    25.7474  -18.8227
            10  C1z C    26.6337  -17.8899
            11  C1x C    28.6392  -19.4756
            12  C1x C    27.9862  -18.1231
            13  C1a C    29.1056  -16.4439
            14  C1a C    27.2866  -15.4644
            15  C1a C    25.7474  -17.0037
            16  O1a O    24.7213  -17.9365
            17  O3c O    20.5597  -19.1387
            18  O3c O    22.5396  -19.1387
            19  C8y C    20.3373  -20.8287
            20  C8x C    19.1628  -20.1510
            21  C8x C    17.9505  -20.8513
            22  C8y C    17.9509  -22.2513
            23  C8x C    19.1253  -22.9290
            24  C8x C    20.3376  -22.2287
            25  C1a C    16.7118  -22.9673
BOND        27
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     4   6 2
            5     5   7 1
            6     7   8 1
            7     7   9 1
            8     9  10 1
            9     8  11 1
            10   10  12 1
            11   12  11 1
            12    1   8 1
            13   10   1 1
            14    1  13 1
            15    1  14 1
            16   10  15 1
            17    9  16 1
            18    2  17 2
            19    2  18 2
            20    2  19 1
            21   19  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   19  24 1
            27   22  25 1

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