KEGG   DRUG: GlibornurideHelp
Entry
D02427                      Drug                                   

Name
Glibornuride (USAN/INN);
Glutril (TN)
Formula
C18H26N2O4S
Exact mass
366.1613
Mol weight
366.475
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antidiabetic agent
 DG01790  Sulfonamide hypoglycemic
  DG01734  Sulfonamide type sulfonylurea receptor agonist
 DG01508  Sulfonylurea receptor agonist
Remark
ATC code: 
Activity
Antidiabetic
Target
sulfonylurea receptor 1 [HSA:6833] [KO:K05032]
  Pathway
ABC transporters
Insulin secretion
Type II diabetes mellitus
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - hypoglycemic agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BB Sulfonylureas
     A10BB04 Glibornuride
      D02427  Glibornuride (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC (CFTR/MRP) subfamily
    ABCC8 (sulfonylurea receptor 1)
     Glibornuride
      D02427  Glibornuride (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
26944-48-9
PubChem: 
LigandBox: 
NIKKAJI: 
LinkDB All DBs
KCF data Show

ATOM        25
            1   C1z C    27.7996  -16.7237
            2   S4a S    21.5497  -20.1287
            3   N1b N    23.0422  -20.8283
            4   C5a C    24.0683  -20.1287
            5   N1b N    25.2344  -20.7350
            6   O5a O    24.0683  -18.8227
            7   C1y C    26.3071  -20.0353
            8   C1y C    27.3799  -19.2425
            9   C1y C    25.7474  -18.8227
            10  C1z C    26.6337  -17.8899
            11  C1x C    28.6392  -19.4756
            12  C1x C    27.9862  -18.1231
            13  C1a C    29.1056  -16.4439
            14  C1a C    27.2866  -15.4644
            15  C1a C    25.7474  -17.0037
            16  O1a O    24.7213  -17.9365
            17  O3c O    20.5597  -19.1387
            18  O3c O    22.5396  -19.1387
            19  C8y C    20.3373  -20.8287
            20  C8x C    19.1628  -20.1510
            21  C8x C    17.9505  -20.8513
            22  C8y C    17.9509  -22.2513
            23  C8x C    19.1253  -22.9290
            24  C8x C    20.3376  -22.2287
            25  C1a C    16.7118  -22.9673
BOND        27
            1     2   3 1
            2     3   4 1
            3     4   5 1
            4     4   6 2
            5     5   7 1
            6     7   8 1
            7     7   9 1
            8     9  10 1
            9     8  11 1
            10   10  12 1
            11   12  11 1
            12    1   8 1
            13   10   1 1
            14    1  13 1
            15    1  14 1
            16   10  15 1
            17    9  16 1
            18    2  17 2
            19    2  18 2
            20    2  19 1
            21   19  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   19  24 1
            27   22  25 1

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