KEGG   DRUG: BivalirudinHelp
Entry
D03136                      Drug                                   

Name
Bivalirudin (USAN/INN);
Angiomax (TN)
Product
  Generic
Formula
C98H138N24O33
Exact mass
2178.9858
Mol weight
2180.2853
Sequence
FPRPGGGGNG DFEEIPEEYL
  Type
Peptide
Class
Cardiovascular agent
 DG01511  Thrombin inhibitor
 DG01950  Antithrombotic agent
  DG01511  Thrombin inhibitor
Remark
ATC code: 
Efficacy
Anticoagulant, Thrombin inhibitor
Comment
Peptide
Hirudin derivative
Target
F2 [HSA:2147] [KO:K01313]
  Pathway
Complement and coagulation cascades
Regulation of actin cytoskeleton
Regulation of actin cytoskeleton
Interaction
Drug interaction
Structure map
Antithrombosis agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AE Direct thrombin inhibitors
     B01AE06 Bivalirudin
      D03136  Bivalirudin (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   thrombin
    Bivalirudin
     D03136  Bivalirudin (USAN/INN)
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D03136
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D03136
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D03136
BRITE hierarchy
Other DBs
CAS: 
128270-60-0
PubChem: 
DrugBank: 
LinkDB All DBs

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