| Entry |
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| Name |
Deferasirox (JAN/USAN/INN);
Exjade (TN)
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| Product |
|
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| Formula |
C21H15N3O4
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| Exact mass |
373.1063
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| Mol weight |
373.3615
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| Structure |
     |
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| Activity |
Treatment of iron overload [iron chelator] [DS: H00228]
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| Remark |
Therapeutic category: ATC code: |
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| Metabolism |
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| Interaction |
CYP induction: CYP3A4 [HSA: 1576]
CYP inhibition: CYP1A2 [HSA: 1544], CYP2C8 [HSA: 1558]
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
392 Antidotes
3929 Others
D03669 Deferasirox (JAN/USAN/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
V VARIOUS
V03 ALL OTHER THERAPEUTIC PRODUCTS
V03A ALL OTHER THERAPEUTIC PRODUCTS
V03AC Iron chelating agents
V03AC03 Deferasirox
D03669 Deferasirox (JAN/USAN/INN)
USP drug classification [BR:br08302]
Therapeutic Nutrients / Minerals / Electrolytes
Electrolyte / Mineral Modifiers
Deferasirox
D03669 Deferasirox (JAN/USAN/INN)
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| Other DBs |
CAS: 201530-41-8 PubChem: DrugBank: LigandBox: |
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| KCF data |
ATOM 28
1 N5x N 8.9600 -13.9300
2 C8y C 8.9600 -15.3300
3 N5x N 10.2915 -15.7626
4 N4y N 11.1144 -14.6300
5 C8y C 10.2915 -13.4974
6 C8y C 12.5144 -14.6300
7 C8x C 13.2182 -15.8492
8 C8x C 14.6182 -15.8492
9 C8y C 15.3183 -14.6368
10 C8x C 14.6145 -13.4177
11 C8x C 13.2145 -13.4176
12 C6a C 16.7300 -14.6370
13 O6a O 17.4331 -13.4194
14 O6a O 17.4269 -15.8442
15 C8y C 7.7476 -16.0300
16 C8x C 6.5521 -15.3396
17 C8x C 5.3396 -16.0395
18 C8x C 5.3394 -17.4395
19 C8x C 6.5349 -18.1299
20 C8y C 7.7474 -17.4300
21 O1a O 8.9766 -18.1400
22 C8y C 10.2915 -12.0974
23 C8x C 11.4973 -11.4012
24 C8x C 11.4974 -10.0012
25 C8x C 10.2850 -9.3012
26 C8x C 9.0791 -9.9973
27 C8y C 9.0791 -11.3973
28 O1a O 7.8771 -12.0915
BOND 31
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 1
5 1 5 2
6 4 6 1
7 6 7 2
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 6 11 1
13 9 12 1
14 12 13 2
15 12 14 1
16 2 15 1
17 15 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 15 20 1
23 20 21 1
24 5 22 1
25 22 23 2
26 23 24 1
27 24 25 2
28 25 26 1
29 26 27 2
30 22 27 1
31 27 28 1
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