KEGG   DRUG: Dibotermin alfa
Entry
D03779                      Drug                                   
Name
Dibotermin alfa (USAN/INN)
Sequence
QAKHKQRKRL KSSCKRHPLY VDFSDVGWND WIVAPPGYHA FYCHGECPFP LADHLNSTNH
AIVQTLVNSV NSKIPKACCV PTELSAISML YLDENEKVVL KNYQDMVVEG CGCR
  Type
Peptide
Remark
ATC code: M05BC01
Efficacy
Osteoinductive
Comment
Recombinant human bone morphogenetic protein-2 (BMP2) [HSA:650] [KO:K04662]
Osteoinductive agent for use in orthopaedic surgery, dental/craniofacial surgery, or spine surgery, as an adjunct to standard care or as a replacement for autogenous bone graft
Target
BMPR2 [HSA:659] [KO:K04671]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M05 DRUGS FOR TREATMENT OF BONE DISEASES
   M05B DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
    M05BC Bone morphogenetic proteins
     M05BC01 Dibotermin alfa
      D03779  Dibotermin alfa (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Receptor serine/threonine kinases (RSTK)
   TGFBR2 family
    BMPR2
     D03779  Dibotermin alfa (USAN/INN)
Other DBs
CAS: 246539-15-1
PubChem: 17397868
LinkDB

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