| Entry |
|
|---|
| Name |
Dirlotapide (USAN/INN);
Slentrol [veterinary] (TN) |
|---|
| Formula |
C40H33F3N4O3
|
|---|
| Exact mass |
674.2505
|
|---|
| Mol weight |
674.71
|
|---|
| Structure |
|
|---|
| Efficacy |
Antiobesity (veterinary), Gut microsomal triglyceride transport protein (gMTP) inhibitor |
|---|
| Comment |
Not for use in humans.
veterinary medicine - Treatment of obesity in companion animals (dogs)
|
|---|
| Target |
|
|---|
| Pathway |
| ko04975 | Fat digestion and absorption |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 50
1 C8x C 23.1000 -16.1700
2 C8y C 23.1000 -14.7700
3 C8x C 21.8400 -14.0700
4 C8y C 20.6500 -14.7700
5 C8y C 20.6500 -16.1700
6 C8x C 21.8400 -16.8700
7 C8x C 19.3200 -14.2800
8 C8y C 18.4800 -15.4700
9 N4y N 19.3200 -16.5900
10 C1a C 18.9000 -17.9200
11 C5a C 17.0800 -15.4700
12 N1b N 24.2900 -14.0700
13 N1b N 16.3800 -14.2100
14 O5a O 16.3800 -16.6600
15 C1c C 14.9800 -14.2100
16 C5a C 14.3500 -13.0200
17 N1c N 12.8800 -13.0200
18 C8y C 14.2800 -15.4700
19 C8x C 12.8800 -15.4700
20 C8x C 12.1800 -16.6600
21 C8x C 12.8800 -17.9200
22 C8x C 14.2800 -17.9200
23 C8x C 14.9800 -16.6600
24 O5a O 14.9800 -11.8300
25 C1a C 12.1800 -14.2800
26 C1b C 12.1800 -11.8300
27 C8y C 10.7800 -11.8300
28 C8x C 10.0800 -10.6400
29 C8x C 8.6800 -10.6400
30 C8x C 7.9800 -11.8300
31 C8x C 8.6800 -13.0200
32 C8x C 10.0800 -13.0200
33 C5a C 25.4800 -14.7000
34 C8y C 26.6700 -14.0700
35 O5a O 25.4800 -16.1700
36 C8y C 27.8600 -14.7000
37 C8x C 29.1200 -14.0000
38 C8x C 29.1200 -12.6000
39 C8x C 27.8600 -11.9700
40 C8x C 26.6700 -12.6700
41 C8y C 27.8600 -16.1700
42 C8x C 26.6700 -16.8700
43 C8x C 26.6700 -18.2700
44 C8y C 27.8600 -18.9700
45 C8x C 29.1200 -18.2700
46 C8x C 29.1200 -16.8700
47 C1d C 27.8600 -20.3700
48 X F 27.8600 -21.7700
49 X F 29.2600 -20.3700
50 X F 26.4600 -20.3700
BOND 55
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 5 9 1
11 9 10 1
12 8 11 1
13 2 12 1
14 11 13 1
15 11 14 2
16 13 15 1
17 15 16 1
18 16 17 1
19 15 18 1 #Up
20 18 19 2
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 18 23 1
26 16 24 2
27 17 25 1
28 17 26 1
29 26 27 1
30 27 28 2
31 28 29 1
32 29 30 2
33 30 31 1
34 31 32 2
35 27 32 1
36 12 33 1
37 33 34 1
38 33 35 2
39 34 36 2
40 36 37 1
41 37 38 2
42 38 39 1
43 39 40 2
44 34 40 1
45 36 41 1
46 41 42 2
47 42 43 1
48 43 44 2
49 44 45 1
50 45 46 2
51 41 46 1
52 44 47 1
53 47 48 1
54 47 49 1
55 47 50 1
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|---|
