| Entry |
|
|---|
| Name |
Guanabenz (USAN/INN) |
|---|
| Formula |
C8H8Cl2N4
|
|---|
| Exact mass |
230.0126
|
|---|
| Mol weight |
231.08
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01738 Centrally-acting antiadrenergic
DG03231 Antihypertensive
|
|---|
| Remark |
| Product (DG01230): | D00605<JP> |
|
|---|
| Efficacy |
Antihypertensive, alpha2-Adrenergic receptor agonist |
|---|
| Comment |
Guanidine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Structure map |
| map07215 | alpha-Adrenergic receptor agonists/antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01738 Centrally-acting antiadrenergic
DG01230 Guanabenz
D04375 Guanabenz
DG03231 Antihypertensive
DG01230 Guanabenz
D04375 Guanabenz
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA2
D04375 Guanabenz (USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01738 Centrally-acting antiadrenergic
DG01230 Guanabenz
DG03231 Antihypertensive
DG01230 Guanabenz
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 14
1 C8y C 25.4195 -16.1356
2 C8y C 25.4136 -17.5269
3 C8y C 26.6246 -15.4253
4 C2b C 24.2028 -15.4310
5 C8x C 26.6246 -18.2255
6 X Cl 24.1969 -18.2198
7 C8x C 27.8354 -16.1297
8 X Cl 26.6187 -14.0222
9 N2b N 22.9977 -16.1356
10 C8x C 27.8354 -17.5269
11 N1b N 21.7868 -15.4310
12 C2c C 20.5702 -16.1356
13 N1a N 19.3592 -15.4310
14 N2a N 20.5702 -17.5386
BOND 14
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 2
9 5 10 1
10 9 11 1
11 11 12 1
12 12 13 1
13 12 14 2
14 7 10 2
|
|---|
