KEGG   DRUG: PixantroneHelp
Entry
D05522                      Drug                                   

Name
Pixantrone (USAN/INN);
Pixuvri (TN)
Formula
C17H19N5O2
Exact mass
325.1539
Mol weight
325.3651
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antineoplastic
 DG01727  Anthraquinone antineoplastic
Other
 DG01529  Topoisomerase inhibitor
  DG01527  Topoisomerase II inhibitor
Remark
ATC code: 
Chemical group: 
Activity
Antineoplastic
Comment
anthraquinone derivative
Target
topoisomerase II [HSA:7153 7155] [KO:K03164]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01D CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
    L01DB Anthracyclines and related substances
     L01DB11 Pixantrone
      D05522  Pixantrone (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
144510-96-3
PubChem: 
LigandBox: 
LinkDB All DBs
KCF data Show

ATOM        24
            1   N5x N     9.3100  -17.9200
            2   C8x C     9.3100  -19.3200
            3   C8x C    10.5224  -20.0200
            4   C8y C    11.7349  -19.3200
            5   C8y C    11.7349  -17.9200
            6   C8x C    10.5224  -17.2200
            7   C5x C    12.9473  -20.0200
            8   C8y C    14.1597  -19.3200
            9   C8y C    14.1597  -17.9200
            10  C5x C    12.9473  -17.2200
            11  C8y C    15.3722  -20.0200
            12  C8x C    16.5846  -19.3200
            13  C8x C    16.5846  -17.9200
            14  C8y C    15.3722  -17.2200
            15  O5x O    12.9473  -15.8200
            16  O5x O    12.9473  -21.4200
            17  N1b N    15.3722  -15.8203
            18  C1b C    16.6054  -15.1080
            19  N1b N    15.3722  -21.4197
            20  C1b C    16.6054  -22.1320
            21  C1b C    17.8115  -21.4359
            22  N1a N    18.9933  -22.1184
            23  C1b C    17.8115  -15.8041
            24  N1a N    18.9933  -15.1216
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    8  11 2
            13   11  12 1
            14   12  13 2
            15   13  14 1
            16    9  14 2
            17   10  15 2
            18    7  16 2
            19   14  17 1
            20   17  18 1
            21   11  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 1
            25   18  23 1
            26   23  24 1

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