| Entry |
|
|---|
| Name |
Pixantrone (USAN/INN);
Pixuvri (TN) |
|---|
| Formula |
C17H19N5O2
|
|---|
| Exact mass |
325.1539
|
|---|
| Mol weight |
325.3651
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01682 Anthracycline antineoplastic
DG01727 Anthraquinone antineoplastic
DG01529 Topoisomerase inhibitor
DG01527 Topoisomerase II inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Topoisomerase II inhibitor |
|---|
| Comment |
anthraquinone derivative
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01D CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
L01DB Anthracyclines and related substances
L01DB11 Pixantrone
D05522 Pixantrone (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01682 Anthracycline antineoplastic
DG00704 Pixantrone
D05522 Pixantrone
DG01727 Anthraquinone antineoplastic
DG00704 Pixantrone
D05522 Pixantrone
DG01529 Topoisomerase inhibitor
DG01527 Topoisomerase II inhibitor
DG00704 Pixantrone
D05522 Pixantrone
Target-based classification of drugs [BR:br08310]
Enzymes
Isomerases (EC5)
DNA topoisomerase
TOP2
D05522 Pixantrone (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01682 Anthracycline antineoplastic
DG00704 Pixantrone
DG01727 Anthraquinone antineoplastic
DG00704 Pixantrone
DG01529 Topoisomerase inhibitor
DG01527 Topoisomerase II inhibitor
DG00704 Pixantrone
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 24
1 N5x N 9.3100 -17.9200
2 C8x C 9.3100 -19.3200
3 C8x C 10.5224 -20.0200
4 C8y C 11.7349 -19.3200
5 C8y C 11.7349 -17.9200
6 C8x C 10.5224 -17.2200
7 C5x C 12.9473 -20.0200
8 C8y C 14.1597 -19.3200
9 C8y C 14.1597 -17.9200
10 C5x C 12.9473 -17.2200
11 C8y C 15.3722 -20.0200
12 C8x C 16.5846 -19.3200
13 C8x C 16.5846 -17.9200
14 C8y C 15.3722 -17.2200
15 O5x O 12.9473 -15.8200
16 O5x O 12.9473 -21.4200
17 N1b N 15.3722 -15.8203
18 C1b C 16.6054 -15.1080
19 N1b N 15.3722 -21.4197
20 C1b C 16.6054 -22.1320
21 C1b C 17.8115 -21.4359
22 N1a N 18.9933 -22.1184
23 C1b C 17.8115 -15.8041
24 N1a N 18.9933 -15.1216
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 9 14 2
17 10 15 2
18 7 16 2
19 14 17 1
20 17 18 1
21 11 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 18 23 1
26 23 24 1
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