KEGG   DRUG: D06551Help
Entry
D06551                      Drug                                   

Name
Afimoxifene (USAN/INN);
Tamogel (TN)
Formula
C26H29NO2
Exact mass
387.2198
Mol weight
387.514
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Local treatment of estrogen dependent conditions of the breast
Remark
Drug group: 
Comment
Selective estrogen receptor modulators (SERMs)
Target
estrogen receptor 1 agonist/antagonist [HSA:2099] [KO:K08550];
estrogen receptor 2 agonist/antagonist [HSA:2100] [KO:K08551]
Brite
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   Estrogen receptor
    estrogen receptor 1
     Afimoxifene
      D06551  Afimoxifene (USAN/INN)
    estrogen receptor 2
     Afimoxifene
      D06551  Afimoxifene (USAN/INN)
Phytochemicals used as drugs [BR:br08306]
 Phenylpropanoids and related compounds
  Stilbenoids
   Stilbenes
    D06551  Afimoxifene (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
68392-35-8
PubChem: 
PDB-CCD: 
LigandBox: 
LinkDB All DBs
KCF data Show

ATOM        29
            1   C8x C    13.0900  -17.2900
            2   C8y C    13.0900  -18.6900
            3   C8x C    14.3024  -19.3900
            4   C8x C    15.5149  -18.6900
            5   C8y C    15.5149  -17.2900
            6   C8x C    14.3024  -16.5900
            7   C8x C    17.9397  -18.6900
            8   C8y C    17.9397  -17.2900
            9   C2c C    16.7273  -16.5900
            10  C8x C    19.1522  -19.3900
            11  C8y C    20.3646  -18.6900
            12  C8x C    20.3646  -17.2900
            13  C8x C    19.1522  -16.5900
            14  C2c C    16.7273  -15.1900
            15  O1a O    11.8776  -19.3900
            16  C8y C    17.9418  -14.4888
            17  C1b C    15.5169  -14.4912
            18  C1a C    14.3045  -15.1912
            19  O2a O    21.5811  -19.3923
            20  C1b C    22.7786  -18.7008
            21  C1b C    23.9649  -19.3857
            22  N1c N    25.1567  -18.6974
            23  C1a C    26.3459  -19.3839
            24  C1a C    25.1567  -17.2903
            25  C8x C    19.1383  -15.1798
            26  C8x C    20.3508  -14.4799
            27  C8x C    20.3509  -13.0799
            28  C8x C    19.1544  -12.3890
            29  C8x C    17.9419  -13.0888
BOND        31
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 1
            8     8   9 1
            9     5   9 1
            10    7  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14    8  13 2
            15    9  14 2
            16    2  15 1
            17   14  16 1
            18   14  17 1
            19   17  18 1
            20   11  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   22  24 1
            26   16  25 2
            27   25  26 1
            28   26  27 2
            29   27  28 1
            30   28  29 2
            31   16  29 1

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