KEGG   DRUG: D06551Help
Entry
D06551                      Drug                                   

Name
Afimoxifene (USAN/INN);
Tamogel (TN)
Formula
C26H29NO2
Exact mass
387.2198
Mol weight
387.514
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Local treatment of estrogen dependent conditions of the breast
Comment
Selective estrogen receptor modulators (SERMs)
Target
estrogen receptor 1 agonist/antagonist [HSA:2099] [KO:K08550];
estrogen receptor 2 agonist/antagonist [HSA:2100] [KO:K08551]
Brite
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   Estrogen receptor
    estrogen receptor 1
     Afimoxifene
      D06551  Afimoxifene (USAN/INN)
    estrogen receptor 2
     Afimoxifene
      D06551  Afimoxifene (USAN/INN)
Phytochemicals used as drugs [BR:br08306]
 Phenylpropanoids and related compounds
  Stilbenoids
   Stilbenes
    D06551  Afimoxifene (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
68392-35-8
PubChem: 
PDB-CCD: 
LigandBox: 
LinkDB All DBs
KCF data Show

ATOM        29
            1   C8x C    13.0900  -17.2900
            2   C8y C    13.0900  -18.6900
            3   C8x C    14.3024  -19.3900
            4   C8x C    15.5149  -18.6900
            5   C8y C    15.5149  -17.2900
            6   C8x C    14.3024  -16.5900
            7   C8x C    17.9397  -18.6900
            8   C8y C    17.9397  -17.2900
            9   C2c C    16.7273  -16.5900
            10  C8x C    19.1522  -19.3900
            11  C8y C    20.3646  -18.6900
            12  C8x C    20.3646  -17.2900
            13  C8x C    19.1522  -16.5900
            14  C2c C    16.7273  -15.1900
            15  O1a O    11.8776  -19.3900
            16  C8y C    17.9418  -14.4888
            17  C1b C    15.5169  -14.4912
            18  C1a C    14.3045  -15.1912
            19  O2a O    21.5811  -19.3923
            20  C1b C    22.7786  -18.7008
            21  C1b C    23.9649  -19.3857
            22  N1c N    25.1567  -18.6974
            23  C1a C    26.3459  -19.3839
            24  C1a C    25.1567  -17.2903
            25  C8x C    19.1383  -15.1798
            26  C8x C    20.3508  -14.4799
            27  C8x C    20.3509  -13.0799
            28  C8x C    19.1544  -12.3890
            29  C8x C    17.9419  -13.0888
BOND        31
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 1
            8     8   9 1
            9     5   9 1
            10    7  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14    8  13 2
            15    9  14 2
            16    2  15 1
            17   14  16 1
            18   14  17 1
            19   17  18 1
            20   11  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   22  24 1
            26   16  25 2
            27   25  26 1
            28   26  27 2
            29   27  28 1
            30   28  29 2
            31   16  29 1

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